6NMX

Threonine synthase from Bacillus subtilis ATCC 6633 with PLP and APPA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003941	molecular_function	L-serine ammonia-lyase activity
A	0004794	molecular_function	threonine deaminase activity
A	0004795	molecular_function	threonine synthase activity
A	0006520	biological_process	amino acid metabolic process
A	0006565	biological_process	L-serine catabolic process
A	0006567	biological_process	threonine catabolic process
A	0009088	biological_process	threonine biosynthetic process
A	0009097	biological_process	isoleucine biosynthetic process
A	0016829	molecular_function	lyase activity
A	0030170	molecular_function	pyridoxal phosphate binding
B	0003941	molecular_function	L-serine ammonia-lyase activity
B	0004794	molecular_function	threonine deaminase activity
B	0004795	molecular_function	threonine synthase activity
B	0006520	biological_process	amino acid metabolic process
B	0006565	biological_process	L-serine catabolic process
B	0006567	biological_process	threonine catabolic process
B	0009088	biological_process	threonine biosynthetic process
B	0009097	biological_process	isoleucine biosynthetic process
B	0016829	molecular_function	lyase activity
B	0030170	molecular_function	pyridoxal phosphate binding
C	0003941	molecular_function	L-serine ammonia-lyase activity
C	0004794	molecular_function	threonine deaminase activity
C	0004795	molecular_function	threonine synthase activity
C	0006520	biological_process	amino acid metabolic process
C	0006565	biological_process	L-serine catabolic process
C	0006567	biological_process	threonine catabolic process
C	0009088	biological_process	threonine biosynthetic process
C	0009097	biological_process	isoleucine biosynthetic process
C	0016829	molecular_function	lyase activity
C	0030170	molecular_function	pyridoxal phosphate binding
D	0003941	molecular_function	L-serine ammonia-lyase activity
D	0004794	molecular_function	threonine deaminase activity
D	0004795	molecular_function	threonine synthase activity
D	0006520	biological_process	amino acid metabolic process
D	0006565	biological_process	L-serine catabolic process
D	0006567	biological_process	threonine catabolic process
D	0009088	biological_process	threonine biosynthetic process
D	0009097	biological_process	isoleucine biosynthetic process
D	0016829	molecular_function	lyase activity
D	0030170	molecular_function	pyridoxal phosphate binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	26
Details	binding site for residue LJS A 401

Chain	Residue
A	PHE58
A	ARG158
A	VAL184
A	GLY185
A	ASN186
A	ALA187
A	GLY188
A	ASN189
A	ALA237
A	ILE238
A	GLU284
A	LYS59
A	SER287
A	THR314
A	HOH524
A	HOH536
A	HOH560
A	HOH572
A	HOH605
A	SER82
A	THR83
A	ASN85
A	THR86
A	PHE132
A	ASN152
A	SER153

---

site_id	AC2
Number of Residues	26
Details	binding site for residue LJS B 401

Chain	Residue
B	PHE58
B	LYS59
B	SER82
B	THR83
B	ASN85
B	THR86
B	PHE132
B	ASN152
B	SER153
B	ARG158
B	VAL184
B	GLY185
B	ASN186
B	ALA187
B	GLY188
B	ASN189
B	ALA237
B	ILE238
B	ILE240
B	GLU284
B	THR314
B	HOH525
B	HOH539
B	HOH556
B	HOH562
B	HOH614

---

site_id	AC3
Number of Residues	26
Details	binding site for residue LJS C 401

Chain	Residue
C	PHE58
C	LYS59
C	SER82
C	THR83
C	ASN85
C	THR86
C	PHE132
C	ASN152
C	SER153
C	ARG158
C	VAL184
C	GLY185
C	ASN186
C	ALA187
C	GLY188
C	ASN189
C	ALA237
C	ILE238
C	ILE240
C	GLU284
C	THR314
C	HOH517
C	HOH537
C	HOH563
C	HOH606
C	HOH667

---

site_id	AC4
Number of Residues	25
Details	binding site for residue LJS D 401

Chain	Residue
D	HOH539
D	HOH562
D	HOH567
D	HOH569
D	PHE58
D	LYS59
D	SER82
D	THR83
D	ASN85
D	THR86
D	PHE132
D	ASN152
D	SER153
D	ARG158
D	VAL184
D	GLY185
D	ASN186
D	ALA187
D	GLY188
D	ASN189
D	ALA237
D	ILE240
D	GLU284
D	THR314
D	HOH522

---

Functional Information from PROSITE/UniProt

site_id	PS00165
Number of Residues	14
Details	DEHYDRATASE_SER_THR Serine/threonine dehydratases pyridoxal-phosphate attachment site. Egvnp.TGSFKDRGM

Chain	Residue	Details
A	GLU50-MET63

---