6NLR
Crystal structure of the putative histidinol phosphatase hisK from Listeria monocytogenes with trinuclear metals determined by PIXE revealing sulphate ion in active site. Based on PIXE analysis and original date from 3DCP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000105 | biological_process | L-histidine biosynthetic process |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004401 | molecular_function | histidinol-phosphatase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000105 | biological_process | L-histidine biosynthetic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004401 | molecular_function | histidinol-phosphatase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000105 | biological_process | L-histidine biosynthetic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004401 | molecular_function | histidinol-phosphatase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue MN A 301 |
| Chain | Residue |
| A | HIS14 |
| A | HIS40 |
| A | HIS260 |
| A | SO4304 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue MN A 302 |
| Chain | Residue |
| A | HOH401 |
| A | HOH424 |
| A | GLU93 |
| A | HIS123 |
| A | HIS181 |
| A | CO303 |
| A | SO4304 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue CO A 303 |
| Chain | Residue |
| A | HIS6 |
| A | HIS8 |
| A | GLU93 |
| A | ASP258 |
| A | MN302 |
| A | SO4304 |
| A | HOH424 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | HIS8 |
| A | HIS14 |
| A | HIS40 |
| A | GLU93 |
| A | HIS123 |
| A | ASP258 |
| A | HIS260 |
| A | MN301 |
| A | MN302 |
| A | CO303 |
| A | HOH401 |
| A | HOH424 |
| A | HOH518 |
| A | HOH544 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue CO B 301 |
| Chain | Residue |
| B | HIS6 |
| B | HIS8 |
| B | GLU93 |
| B | ASP258 |
| B | FE303 |
| B | SO4305 |
| B | HOH403 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue FE B 302 |
| Chain | Residue |
| B | HIS14 |
| B | HIS40 |
| B | HIS260 |
| B | SO4305 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue FE B 303 |
| Chain | Residue |
| B | GLU93 |
| B | HIS123 |
| B | HIS181 |
| B | CO301 |
| B | SO4305 |
| B | HOH401 |
| B | HOH403 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue CA B 304 |
| Chain | Residue |
| B | TYR141 |
| B | PHE152 |
| B | ALA155 |
| B | CYS185 |
| site_id | AC9 |
| Number of Residues | 13 |
| Details | binding site for residue SO4 B 305 |
| Chain | Residue |
| B | HIS8 |
| B | HIS14 |
| B | HIS40 |
| B | GLU93 |
| B | HIS123 |
| B | ASP258 |
| B | HIS260 |
| B | CO301 |
| B | FE302 |
| B | FE303 |
| B | HOH401 |
| B | HOH403 |
| B | HOH454 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue MN C 301 |
| Chain | Residue |
| C | HIS14 |
| C | HIS40 |
| C | HIS260 |
| C | SO4305 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue CO C 302 |
| Chain | Residue |
| C | HIS6 |
| C | HIS8 |
| C | GLU93 |
| C | ASP258 |
| C | FE303 |
| C | SO4305 |
| C | HOH404 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue FE C 303 |
| Chain | Residue |
| C | GLU93 |
| C | HIS123 |
| C | HIS181 |
| C | CO302 |
| C | SO4305 |
| C | HOH404 |
| C | HOH405 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue CA C 304 |
| Chain | Residue |
| C | GLN186 |
| C | GLN189 |
| C | THR196 |
| C | GLU235 |
| C | HOH465 |
| site_id | AD5 |
| Number of Residues | 14 |
| Details | binding site for residue SO4 C 305 |
| Chain | Residue |
| C | FE303 |
| C | HOH404 |
| C | HOH405 |
| C | HOH413 |
| C | HOH508 |
| C | HIS8 |
| C | HIS14 |
| C | HIS40 |
| C | GLU93 |
| C | HIS123 |
| C | ASP258 |
| C | HIS260 |
| C | MN301 |
| C | CO302 |
