Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004517 | molecular_function | nitric-oxide synthase activity |
A | 0006809 | biological_process | nitric oxide biosynthetic process |
B | 0004517 | molecular_function | nitric-oxide synthase activity |
B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 16 |
Details | binding site for residue HEM A 801 |
Chain | Residue |
A | HIS341 |
A | H4B802 |
A | KNS803 |
A | ACT804 |
A | HOH933 |
A | HOH935 |
A | HOH963 |
A | HOH987 |
A | TRP409 |
A | ARG414 |
A | CYS415 |
A | PHE584 |
A | SER585 |
A | TRP587 |
A | MET589 |
A | TYR706 |
site_id | AC2 |
Number of Residues | 12 |
Details | binding site for residue H4B A 802 |
Chain | Residue |
A | SER334 |
A | ARG596 |
A | VAL677 |
A | TRP678 |
A | HEM801 |
A | HOH933 |
A | HOH962 |
A | HOH997 |
B | TRP676 |
B | PHE691 |
B | HIS692 |
B | GLU694 |
site_id | AC3 |
Number of Residues | 11 |
Details | binding site for residue KNS A 803 |
Chain | Residue |
A | MET336 |
A | PRO565 |
A | VAL567 |
A | MET570 |
A | PHE584 |
A | GLY586 |
A | TRP587 |
A | TYR588 |
A | GLU592 |
A | TYR706 |
A | HEM801 |
site_id | AC4 |
Number of Residues | 3 |
Details | binding site for residue ACT A 804 |
Chain | Residue |
A | GLY417 |
A | TRP587 |
A | HEM801 |
site_id | AC5 |
Number of Residues | 4 |
Details | binding site for residue ZN A 805 |
Chain | Residue |
A | CYS326 |
A | CYS331 |
B | CYS326 |
B | CYS331 |
site_id | AC6 |
Number of Residues | 17 |
Details | binding site for residue HEM B 801 |
Chain | Residue |
B | HIS341 |
B | TRP409 |
B | ALA412 |
B | ARG414 |
B | CYS415 |
B | PHE584 |
B | SER585 |
B | GLY586 |
B | TRP587 |
B | MET589 |
B | TRP678 |
B | PHE704 |
B | TYR706 |
B | H4B802 |
B | KNS803 |
B | HOH907 |
B | HOH977 |
site_id | AC7 |
Number of Residues | 12 |
Details | binding site for residue H4B B 802 |
Chain | Residue |
A | TRP676 |
A | PHE691 |
A | HIS692 |
A | GLN693 |
A | GLU694 |
A | HOH909 |
B | SER334 |
B | ARG596 |
B | VAL677 |
B | TRP678 |
B | HEM801 |
B | HOH1010 |
site_id | AC8 |
Number of Residues | 8 |
Details | binding site for residue KNS B 803 |
Chain | Residue |
B | VAL567 |
B | MET570 |
B | PHE584 |
B | GLY586 |
B | TRP587 |
B | GLU592 |
B | TYR706 |
B | HEM801 |
site_id | AC9 |
Number of Residues | 4 |
Details | binding site for residue ACT B 804 |
Chain | Residue |
B | GLY417 |
B | GLN420 |
B | TRP587 |
B | VAL649 |
Functional Information from PROSITE/UniProt
site_id | PS60001 |
Number of Residues | 8 |
Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
Chain | Residue | Details |
A | ARG414-TRP421 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | SER334 | |
B | SER334 | |
B | GLN478 | |
B | TRP587 | |
B | TYR588 | |
B | GLU592 | |
B | VAL677 | |
B | TRP678 | |
B | PHE691 | |
B | TYR706 | |
A | GLN478 | |
A | TRP587 | |
A | TYR588 | |
A | GLU592 | |
A | VAL677 | |
A | TRP678 | |
A | PHE691 | |
A | TYR706 | |
Chain | Residue | Details |
A | CYS415 | |
B | CYS415 | |