Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue HEM A 801 |
| Chain | Residue |
| A | TRP409 |
| A | MET589 |
| A | GLU592 |
| A | TRP678 |
| A | PHE704 |
| A | TYR706 |
| A | H4B802 |
| A | KL1803 |
| A | HOH901 |
| A | HOH930 |
| A | HOH940 |
| A | ALA412 |
| A | ARG414 |
| A | CYS415 |
| A | SER457 |
| A | PHE584 |
| A | SER585 |
| A | GLY586 |
| A | TRP587 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | binding site for residue H4B A 802 |
| Chain | Residue |
| A | SER334 |
| A | ARG596 |
| A | VAL677 |
| A | TRP678 |
| A | HEM801 |
| A | KL1803 |
| A | HOH905 |
| A | HOH930 |
| A | HOH978 |
| A | HOH988 |
| A | HOH1007 |
| B | TRP676 |
| B | PHE691 |
| B | HIS692 |
| B | GLN693 |
| B | GLU694 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue KL1 A 803 |
| Chain | Residue |
| A | VAL567 |
| A | MET570 |
| A | PHE584 |
| A | GLY586 |
| A | TRP587 |
| A | TYR588 |
| A | GLU592 |
| A | TRP678 |
| A | HEM801 |
| A | H4B802 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue ACT A 804 |
| Chain | Residue |
| A | TRP587 |
| A | SER657 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | binding site for residue HEM B 801 |
| Chain | Residue |
| B | TRP409 |
| B | ALA412 |
| B | ARG414 |
| B | CYS415 |
| B | SER457 |
| B | PHE584 |
| B | SER585 |
| B | GLY586 |
| B | TRP587 |
| B | GLU592 |
| B | TRP678 |
| B | PHE704 |
| B | TYR706 |
| B | H4B802 |
| B | KL1803 |
| B | HOH901 |
| B | HOH930 |
| B | HOH941 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | binding site for residue H4B B 802 |
| Chain | Residue |
| A | TRP676 |
| A | PHE691 |
| A | HIS692 |
| A | GLN693 |
| A | GLU694 |
| B | SER334 |
| B | MET336 |
| B | ARG596 |
| B | VAL677 |
| B | TRP678 |
| B | HEM801 |
| B | HOH908 |
| B | HOH941 |
| B | HOH989 |
| B | HOH1019 |
| B | HOH1026 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue KL1 B 803 |
| Chain | Residue |
| B | MET336 |
| B | VAL567 |
| B | MET570 |
| B | GLY586 |
| B | TRP587 |
| B | TYR588 |
| B | GLU592 |
| B | HEM801 |
| B | HOH1092 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue ACT B 804 |
| Chain | Residue |
| B | GLY417 |
| B | TRP587 |
| B | HOH927 |
| B | HOH992 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 805 |
| Chain | Residue |
| A | CYS326 |
| A | CYS331 |
| B | CYS326 |
| B | CYS331 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG414-TRP421 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | SER334 | |
| B | SER334 | |
| B | GLN478 | |
| B | TRP587 | |
| B | TYR588 | |
| B | GLU592 | |
| B | VAL677 | |
| B | TRP678 | |
| B | PHE691 | |
| B | TYR706 | |
| A | GLN478 | |
| A | TRP587 | |
| A | TYR588 | |
| A | GLU592 | |
| A | VAL677 | |
| A | TRP678 | |
| A | PHE691 | |
| A | TYR706 | |
| Chain | Residue | Details |
| A | CYS415 | |
| B | CYS415 | |
