Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue HEM A 801 |
| Chain | Residue |
| A | TRP414 |
| A | H4B802 |
| A | KMS803 |
| A | HOH932 |
| A | HOH950 |
| A | HOH966 |
| A | HOH997 |
| A | HOH1005 |
| A | HOH1017 |
| A | CYS420 |
| A | PHE589 |
| A | SER590 |
| A | TRP592 |
| A | GLU597 |
| A | TRP683 |
| A | PHE709 |
| A | TYR711 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue H4B A 802 |
| Chain | Residue |
| A | SER339 |
| A | ARG601 |
| A | VAL682 |
| A | TRP683 |
| A | HEM801 |
| A | KMS803 |
| A | HOH951 |
| A | HOH966 |
| A | HOH981 |
| A | HOH1056 |
| A | HOH1080 |
| B | TRP681 |
| B | PHE696 |
| B | HIS697 |
| B | GLN698 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue KMS A 803 |
| Chain | Residue |
| A | ARG486 |
| A | TYR567 |
| A | VAL572 |
| A | GLY591 |
| A | TRP592 |
| A | TYR593 |
| A | GLU597 |
| A | HEM801 |
| A | H4B802 |
| A | GOL804 |
| A | HOH966 |
| A | HOH1050 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 804 |
| Chain | Residue |
| A | ASP605 |
| A | SER607 |
| A | KMS803 |
| A | HOH951 |
| B | TRP311 |
| B | HIS697 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 805 |
| Chain | Residue |
| A | GLN369 |
| A | ARG674 |
| A | HOH1011 |
| A | HOH1103 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 806 |
| Chain | Residue |
| A | LYS411 |
| A | LEU429 |
| A | GLN430 |
| A | VAL431 |
| A | HOH983 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 801 |
| Chain | Residue |
| A | CYS331 |
| A | CYS336 |
| B | CYS331 |
| B | CYS336 |
| site_id | AC8 |
| Number of Residues | 18 |
| Details | binding site for residue HEM B 802 |
| Chain | Residue |
| B | TRP414 |
| B | CYS420 |
| B | SER462 |
| B | PHE589 |
| B | SER590 |
| B | GLY591 |
| B | TRP592 |
| B | GLU597 |
| B | TRP683 |
| B | PHE709 |
| B | TYR711 |
| B | H4B803 |
| B | KMS804 |
| B | HOH902 |
| B | HOH924 |
| B | HOH950 |
| B | HOH987 |
| B | HOH1030 |
| site_id | AC9 |
| Number of Residues | 16 |
| Details | binding site for residue H4B B 803 |
| Chain | Residue |
| A | TRP681 |
| A | PHE696 |
| A | HIS697 |
| A | GLN698 |
| A | GLU699 |
| B | SER339 |
| B | MET341 |
| B | ARG601 |
| B | VAL682 |
| B | TRP683 |
| B | HEM802 |
| B | HOH950 |
| B | HOH956 |
| B | HOH982 |
| B | HOH1004 |
| B | HOH1024 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for residue KMS B 804 |
| Chain | Residue |
| B | TYR567 |
| B | VAL572 |
| B | TRP592 |
| B | TYR593 |
| B | GLU597 |
| B | HEM802 |
| B | HOH950 |
| B | GLN483 |
| B | ARG486 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 805 |
| Chain | Residue |
| B | GLN369 |
| B | ARG674 |
| B | HOH989 |
| B | HOH1051 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG419-TRP426 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25286850","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4D1N","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"25286850","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4D1N","evidenceCode":"ECO:0007744"}]} |
