6NF7

Crystal Structure of RT1.Aa-Bu31-10

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
B	0005576	cellular_component	extracellular region
B	0005765	cellular_component	lysosomal membrane
B	0006955	biological_process	immune response
B	0009410	biological_process	response to xenobiotic stimulus
B	0010038	biological_process	response to metal ion
B	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
B	0023026	molecular_function	MHC class II protein complex binding
B	0031902	cellular_component	late endosome membrane
B	0042605	molecular_function	peptide antigen binding
B	0042612	cellular_component	MHC class I protein complex
B	0042613	cellular_component	MHC class II protein complex
B	0046686	biological_process	response to cadmium ion
B	0050778	biological_process	positive regulation of immune response
B	0050870	biological_process	positive regulation of T cell activation
E	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
E	0005576	cellular_component	extracellular region
E	0005765	cellular_component	lysosomal membrane
E	0006955	biological_process	immune response
E	0009410	biological_process	response to xenobiotic stimulus
E	0010038	biological_process	response to metal ion
E	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
E	0023026	molecular_function	MHC class II protein complex binding
E	0031902	cellular_component	late endosome membrane
E	0042605	molecular_function	peptide antigen binding
E	0042612	cellular_component	MHC class I protein complex
E	0042613	cellular_component	MHC class II protein complex
E	0046686	biological_process	response to cadmium ion
E	0050778	biological_process	positive regulation of immune response
E	0050870	biological_process	positive regulation of T cell activation
H	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
H	0005576	cellular_component	extracellular region
H	0005765	cellular_component	lysosomal membrane
H	0006955	biological_process	immune response
H	0009410	biological_process	response to xenobiotic stimulus
H	0010038	biological_process	response to metal ion
H	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
H	0023026	molecular_function	MHC class II protein complex binding
H	0031902	cellular_component	late endosome membrane
H	0042605	molecular_function	peptide antigen binding
H	0042612	cellular_component	MHC class I protein complex
H	0042613	cellular_component	MHC class II protein complex
H	0046686	biological_process	response to cadmium ion
H	0050778	biological_process	positive regulation of immune response
H	0050870	biological_process	positive regulation of T cell activation
K	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
K	0005576	cellular_component	extracellular region
K	0005765	cellular_component	lysosomal membrane
K	0006955	biological_process	immune response
K	0009410	biological_process	response to xenobiotic stimulus
K	0010038	biological_process	response to metal ion
K	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
K	0023026	molecular_function	MHC class II protein complex binding
K	0031902	cellular_component	late endosome membrane
K	0042605	molecular_function	peptide antigen binding
K	0042612	cellular_component	MHC class I protein complex
K	0042613	cellular_component	MHC class II protein complex
K	0046686	biological_process	response to cadmium ion
K	0050778	biological_process	positive regulation of immune response
K	0050870	biological_process	positive regulation of T cell activation
N	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
N	0005576	cellular_component	extracellular region
N	0005765	cellular_component	lysosomal membrane
N	0006955	biological_process	immune response
N	0009410	biological_process	response to xenobiotic stimulus
N	0010038	biological_process	response to metal ion
N	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
N	0023026	molecular_function	MHC class II protein complex binding
N	0031902	cellular_component	late endosome membrane
N	0042605	molecular_function	peptide antigen binding
N	0042612	cellular_component	MHC class I protein complex
N	0042613	cellular_component	MHC class II protein complex
N	0046686	biological_process	response to cadmium ion
N	0050778	biological_process	positive regulation of immune response
N	0050870	biological_process	positive regulation of T cell activation

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCRVEH

Chain	Residue	Details
A	TYR257-HIS263
B	TYR78-HIS84

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	875
Details	Domain: {"description":"Ig-like C1-type"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	445
Details	Region: {"description":"Alpha-1"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	455
Details	Region: {"description":"Alpha-2"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	455
Details	Region: {"description":"Alpha-3"}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	10
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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