6NEG
N191D, F205S mutant of scoulerine-9-O methyltransferase from Thalictrum flavum complexed with S-ADENOSYL-L-HOMOCYSTEINE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008171 | molecular_function | O-methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0046983 | molecular_function | protein dimerization activity |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0008171 | molecular_function | O-methyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0032259 | biological_process | methylation |
| B | 0046983 | molecular_function | protein dimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue SAH A 401 |
| Chain | Residue |
| A | PHE148 |
| A | MET237 |
| A | PHE238 |
| A | LYS250 |
| A | TRP251 |
| A | ASP255 |
| A | HOH519 |
| A | HOH553 |
| A | HOH572 |
| A | HOH604 |
| A | HOH617 |
| A | PHE161 |
| A | MET165 |
| A | SER169 |
| A | GLY193 |
| A | GLU216 |
| A | LEU217 |
| A | VAL220 |
| A | ASN236 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | binding site for residue SAH B 401 |
| Chain | Residue |
| B | PHE148 |
| B | PHE161 |
| B | MET165 |
| B | SER169 |
| B | GLY193 |
| B | GLY194 |
| B | GLU216 |
| B | LEU217 |
| B | VAL220 |
| B | ASN236 |
| B | MET237 |
| B | PHE238 |
| B | LYS250 |
| B | TRP251 |
| B | ASP255 |
| B | HOH537 |
| B | HOH555 |
| B | HOH565 |
| B | HOH601 |
| B | HOH613 |
| B | HOH624 |
| B | HOH637 |
