6NDS

Structure of an HMG-CoA lyase from Acenitobacter baumannii in complex with coenzyme A and 3-methylmalate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004419	molecular_function	hydroxymethylglutaryl-CoA lyase activity
A	0006552	biological_process	L-leucine catabolic process
A	0016829	molecular_function	lyase activity
A	0016833	molecular_function	oxo-acid-lyase activity
A	0046872	molecular_function	metal ion binding
A	0046951	biological_process	ketone body biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	binding site for residue COA A 501

Chain	Residue
A	PHE51
A	ARG115
A	CYS240
A	CIT502
A	HOH652
A	HOH652
A	HOH683
A	HOH722
A	VAL52
A	SER53
A	ILE57
A	ASN84
A	GLY87
A	ARG90
A	ASN113
A	MET114

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site_id	AC2
Number of Residues	12
Details	binding site for residue CIT A 502

Chain	Residue
A	ARG16
A	ASP17
A	GLN20
A	ALA143
A	ALA177
A	THR179
A	HIS207
A	HIS209
A	CYS240
A	COA501
A	ZN507
A	HOH623

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site_id	AC3
Number of Residues	3
Details	binding site for residue ACT A 503

Chain	Residue
A	TYR223
A	GLY263
A	HOH653

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site_id	AC4
Number of Residues	6
Details	binding site for residue ACT A 504

Chain	Residue
A	ASN184
A	GLN187
A	ARG190
A	GLU261
A	ILE262
A	HOH781

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site_id	AC5
Number of Residues	6
Details	binding site for residue ACT A 505

Chain	Residue
A	PRO281
A	ASP287
A	THR288
A	ALA293
A	LYS294
A	HOH628

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site_id	AC6
Number of Residues	6
Details	binding site for residue EDO A 506

Chain	Residue
A	THR68
A	GLY69
A	ILE70
A	HOH655
A	HOH659
A	HOH711

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site_id	AC7
Number of Residues	5
Details	binding site for residue ZN A 507

Chain	Residue
A	ASP17
A	HIS207
A	HIS209
A	CIT502
A	HOH623

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