6NDR
Crystal structure of dTDP-6-deoxy-D-glucose-3,5-epimerase RmlC from Legionella pneumophila Philadelphia 1 in complex with dTDP-4-KETO-L-RHAMNOSE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000271 | biological_process | polysaccharide biosynthetic process |
| A | 0005829 | cellular_component | cytosol |
| A | 0008830 | molecular_function | dTDP-4-dehydrorhamnose 3,5-epimerase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016854 | molecular_function | racemase and epimerase activity |
| A | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
| B | 0000271 | biological_process | polysaccharide biosynthetic process |
| B | 0005829 | cellular_component | cytosol |
| B | 0008830 | molecular_function | dTDP-4-dehydrorhamnose 3,5-epimerase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0016854 | molecular_function | racemase and epimerase activity |
| B | 0019305 | biological_process | dTDP-rhamnose biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 201 |
| Chain | Residue |
| A | GLU15 |
| A | ASN106 |
| A | ARG108 |
| A | HOH316 |
| A | HOH359 |
| A | HOH370 |
| A | HOH407 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 202 |
| Chain | Residue |
| A | GLY99 |
| A | LEU173 |
| A | HOH301 |
| A | HOH305 |
| A | GLN7 |
| A | VAL98 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 203 |
| Chain | Residue |
| A | GLU79 |
| A | ASN175 |
| A | HOH323 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 204 |
| Chain | Residue |
| A | ALA77 |
| A | GLY78 |
| A | GLY104 |
| A | HOH315 |
| A | HOH362 |
| A | HOH422 |
| A | HOH445 |
| B | ARG52 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 205 |
| Chain | Residue |
| A | TYR136 |
| A | ARG184 |
| A | HOH326 |
| A | HOH366 |
| B | LYS33 |
| B | HOH434 |
| site_id | AC6 |
| Number of Residues | 19 |
| Details | binding site for residue TDO A 206 |
| Chain | Residue |
| A | GLN47 |
| A | ASN49 |
| A | ARG59 |
| A | HIS62 |
| A | LYS71 |
| A | HIS118 |
| A | TYR131 |
| A | TYR137 |
| A | GLU142 |
| A | LYS167 |
| A | HOH302 |
| A | HOH306 |
| A | HOH398 |
| A | HOH428 |
| A | HOH482 |
| B | TYR19 |
| B | ARG23 |
| B | PHE26 |
| B | GLU28 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 207 |
| Chain | Residue |
| A | SER29 |
| A | LEU76 |
| A | HOH392 |
| A | HOH405 |
| B | ASN49 |
| B | EDO202 |
| site_id | AC8 |
| Number of Residues | 21 |
| Details | binding site for residue TDO B 201 |
| Chain | Residue |
| A | TYR19 |
| A | ARG23 |
| A | PHE26 |
| A | GLU28 |
| B | GLN47 |
| B | ASN49 |
| B | ARG59 |
| B | HIS62 |
| B | LYS71 |
| B | HIS118 |
| B | TYR131 |
| B | TYR137 |
| B | GLU142 |
| B | LYS167 |
| B | HOH301 |
| B | HOH302 |
| B | HOH317 |
| B | HOH359 |
| B | HOH411 |
| B | HOH414 |
| B | HOH449 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 202 |
| Chain | Residue |
| A | ASN49 |
| A | EDO207 |
| B | SER29 |
| B | LEU76 |
| B | HOH344 |
| B | HOH395 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 203 |
| Chain | Residue |
| B | GLU15 |
| B | ASN106 |
| B | ARG108 |
| B | HOH334 |
| B | HOH339 |
| B | HOH362 |
| B | HOH378 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 204 |
| Chain | Residue |
| B | GLN7 |
| B | VAL98 |
| B | GLY99 |
| B | LEU173 |
| B | HOH305 |
| B | HOH314 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 205 |
| Chain | Residue |
| B | GLU79 |
| B | ASN175 |
| B | HOH476 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 B 206 |
| Chain | Residue |
| B | ALA77 |
| B | GLY78 |
| B | GLY104 |
| B | HOH309 |
| B | HOH336 |
| B | HOH374 |
| B | HOH462 |
| A | ARG52 |
