6NCJ
Structure of HIV-1 Integrase with potent 5,6,7,8-Tetrahydro-1,6-naphthyridine Derivatives Allosteric Site Inhibitors
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0015074 | biological_process | DNA integration |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 301 |
| Chain | Residue |
| A | ARG107 |
| A | GLY197 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | GLU92 |
| A | THR115 |
| A | ASP116 |
| A | ASN120 |
| A | PHE121 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | LYS103 |
| A | ARG107 |
| A | GLU85 |
| A | PHE100 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | GLU96 |
| A | TYR99 |
| A | LYS173 |
| A | HOH422 |
| A | HOH455 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | binding site for residue KJJ A 305 |
| Chain | Residue |
| A | LEU102 |
| A | THR124 |
| A | THR125 |
| A | ALA128 |
| A | ALA129 |
| A | TRP132 |
| A | GLY140 |
| A | GLN168 |
| A | ALA169 |
| A | GLU170 |
| A | HIS171 |
| A | THR174 |
| A | HOH432 |
| A | HOH438 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 306 |
| Chain | Residue |
| A | LYS71 |
| A | ARG166 |
| A | HIS171 |
| A | LEU172 |
| A | HOH411 |
| A | HOH425 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 307 |
| Chain | Residue |
| A | THR66 |
| A | HIS67 |
| A | LYS111 |
| A | LYS136 |
| A | LYS159 |
