6NCA

HLA-A2 (A*02:01) bound to a peptide from the Epstein-Barr virus BRLF1 protein

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0000139	cellular_component	Golgi membrane
a	0002376	biological_process	immune system process
a	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
a	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
a	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
a	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
a	0002715	biological_process	regulation of natural killer cell mediated immunity
a	0002726	biological_process	positive regulation of T cell cytokine production
a	0005198	molecular_function	structural molecule activity
a	0005515	molecular_function	protein binding
a	0005576	cellular_component	extracellular region
a	0005615	cellular_component	extracellular space
a	0005765	cellular_component	lysosomal membrane
a	0005783	cellular_component	endoplasmic reticulum
a	0005788	cellular_component	endoplasmic reticulum lumen
a	0005794	cellular_component	Golgi apparatus
a	0005886	cellular_component	plasma membrane
a	0005925	cellular_component	focal adhesion
a	0006879	biological_process	intracellular iron ion homeostasis
a	0006955	biological_process	immune response
a	0007608	biological_process	sensory perception of smell
a	0007611	biological_process	learning or memory
a	0009897	cellular_component	external side of plasma membrane
a	0009986	cellular_component	cell surface
a	0010038	biological_process	response to metal ion
a	0012507	cellular_component	ER to Golgi transport vesicle membrane
a	0016020	cellular_component	membrane
a	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
a	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
a	0023026	molecular_function	MHC class II protein complex binding
a	0030670	cellular_component	phagocytic vesicle membrane
a	0031901	cellular_component	early endosome membrane
a	0031902	cellular_component	late endosome membrane
a	0031905	cellular_component	early endosome lumen
a	0033572	biological_process	transferrin transport
a	0034756	biological_process	regulation of iron ion transport
a	0034757	biological_process	negative regulation of iron ion transport
a	0035580	cellular_component	specific granule lumen
a	0042605	molecular_function	peptide antigen binding
a	0042612	cellular_component	MHC class I protein complex
a	0042613	cellular_component	MHC class II protein complex
a	0042802	molecular_function	identical protein binding
a	0042803	molecular_function	protein homodimerization activity
a	0042824	cellular_component	MHC class I peptide loading complex
a	0048260	biological_process	positive regulation of receptor-mediated endocytosis
a	0048261	biological_process	negative regulation of receptor-mediated endocytosis
a	0050680	biological_process	negative regulation of epithelial cell proliferation
a	0050768	biological_process	negative regulation of neurogenesis
a	0050778	biological_process	positive regulation of immune response
a	0050870	biological_process	positive regulation of T cell activation
a	0051289	biological_process	protein homotetramerization
a	0055038	cellular_component	recycling endosome membrane
a	0070062	cellular_component	extracellular exosome
a	0071281	biological_process	cellular response to iron ion
a	0071316	biological_process	cellular response to nicotine
a	1904724	cellular_component	tertiary granule lumen
a	1990000	biological_process	amyloid fibril formation
a	1990712	cellular_component	HFE-transferrin receptor complex
a	2000774	biological_process	positive regulation of cellular senescence
a	2000978	biological_process	negative regulation of forebrain neuron differentiation
b	0000139	cellular_component	Golgi membrane
b	0002376	biological_process	immune system process
b	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
b	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
b	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
b	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
b	0002715	biological_process	regulation of natural killer cell mediated immunity
b	0002726	biological_process	positive regulation of T cell cytokine production
b	0005198	molecular_function	structural molecule activity
b	0005515	molecular_function	protein binding
b	0005576	cellular_component	extracellular region
b	0005615	cellular_component	extracellular space
b	0005765	cellular_component	lysosomal membrane
b	0005783	cellular_component	endoplasmic reticulum
b	0005788	cellular_component	endoplasmic reticulum lumen
b	0005794	cellular_component	Golgi apparatus
b	0005886	cellular_component	plasma membrane
b	0005925	cellular_component	focal adhesion
b	0006879	biological_process	intracellular iron ion homeostasis
b	0006955	biological_process	immune response
b	0007608	biological_process	sensory perception of smell
b	0007611	biological_process	learning or memory
b	0009897	cellular_component	external side of plasma membrane
b	0009986	cellular_component	cell surface
b	0010038	biological_process	response to metal ion
b	0012507	cellular_component	ER to Golgi transport vesicle membrane
b	0016020	cellular_component	membrane
b	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
b	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
b	0023026	molecular_function	MHC class II protein complex binding
b	0030670	cellular_component	phagocytic vesicle membrane
b	0031901	cellular_component	early endosome membrane
b	0031902	cellular_component	late endosome membrane
b	0031905	cellular_component	early endosome lumen
b	0033572	biological_process	transferrin transport
b	0034756	biological_process	regulation of iron ion transport
b	0034757	biological_process	negative regulation of iron ion transport
b	0035580	cellular_component	specific granule lumen
b	0042605	molecular_function	peptide antigen binding
b	0042612	cellular_component	MHC class I protein complex
b	0042613	cellular_component	MHC class II protein complex
b	0042802	molecular_function	identical protein binding
b	0042803	molecular_function	protein homodimerization activity
b	0042824	cellular_component	MHC class I peptide loading complex
b	0048260	biological_process	positive regulation of receptor-mediated endocytosis
b	0048261	biological_process	negative regulation of receptor-mediated endocytosis
b	0050680	biological_process	negative regulation of epithelial cell proliferation
b	0050768	biological_process	negative regulation of neurogenesis
b	0050778	biological_process	positive regulation of immune response
b	0050870	biological_process	positive regulation of T cell activation
b	0051289	biological_process	protein homotetramerization
b	0055038	cellular_component	recycling endosome membrane
b	0070062	cellular_component	extracellular exosome
b	0071281	biological_process	cellular response to iron ion
b	0071316	biological_process	cellular response to nicotine
b	1904724	cellular_component	tertiary granule lumen
b	1990000	biological_process	amyloid fibril formation
b	1990712	cellular_component	HFE-transferrin receptor complex
b	2000774	biological_process	positive regulation of cellular senescence
b	2000978	biological_process	negative regulation of forebrain neuron differentiation
c	0000139	cellular_component	Golgi membrane
c	0002376	biological_process	immune system process
c	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
c	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
c	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
c	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
c	0002715	biological_process	regulation of natural killer cell mediated immunity
c	0002726	biological_process	positive regulation of T cell cytokine production
c	0005198	molecular_function	structural molecule activity
c	0005515	molecular_function	protein binding
c	0005576	cellular_component	extracellular region
c	0005615	cellular_component	extracellular space
c	0005765	cellular_component	lysosomal membrane
c	0005783	cellular_component	endoplasmic reticulum
c	0005788	cellular_component	endoplasmic reticulum lumen
c	0005794	cellular_component	Golgi apparatus
c	0005886	cellular_component	plasma membrane
c	0005925	cellular_component	focal adhesion
c	0006879	biological_process	intracellular iron ion homeostasis
c	0006955	biological_process	immune response
c	0007608	biological_process	sensory perception of smell
c	0007611	biological_process	learning or memory
c	0009897	cellular_component	external side of plasma membrane
c	0009986	cellular_component	cell surface
c	0010038	biological_process	response to metal ion
c	0012507	cellular_component	ER to Golgi transport vesicle membrane
c	0016020	cellular_component	membrane
c	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
c	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
c	0023026	molecular_function	MHC class II protein complex binding
c	0030670	cellular_component	phagocytic vesicle membrane
c	0031901	cellular_component	early endosome membrane
c	0031902	cellular_component	late endosome membrane
c	0031905	cellular_component	early endosome lumen
c	0033572	biological_process	transferrin transport
c	0034756	biological_process	regulation of iron ion transport
c	0034757	biological_process	negative regulation of iron ion transport
c	0035580	cellular_component	specific granule lumen
c	0042605	molecular_function	peptide antigen binding
c	0042612	cellular_component	MHC class I protein complex
c	0042613	cellular_component	MHC class II protein complex
c	0042802	molecular_function	identical protein binding
c	0042803	molecular_function	protein homodimerization activity
c	0042824	cellular_component	MHC class I peptide loading complex
c	0048260	biological_process	positive regulation of receptor-mediated endocytosis
c	0048261	biological_process	negative regulation of receptor-mediated endocytosis
c	0050680	biological_process	negative regulation of epithelial cell proliferation
c	0050768	biological_process	negative regulation of neurogenesis
c	0050778	biological_process	positive regulation of immune response
c	0050870	biological_process	positive regulation of T cell activation
c	0051289	biological_process	protein homotetramerization
c	0055038	cellular_component	recycling endosome membrane
c	0070062	cellular_component	extracellular exosome
c	0071281	biological_process	cellular response to iron ion
c	0071316	biological_process	cellular response to nicotine
c	1904724	cellular_component	tertiary granule lumen
c	1990000	biological_process	amyloid fibril formation
c	1990712	cellular_component	HFE-transferrin receptor complex
c	2000774	biological_process	positive regulation of cellular senescence
c	2000978	biological_process	negative regulation of forebrain neuron differentiation
d	0000139	cellular_component	Golgi membrane
d	0002376	biological_process	immune system process
d	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
d	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
d	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
d	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
d	0002715	biological_process	regulation of natural killer cell mediated immunity
d	0002726	biological_process	positive regulation of T cell cytokine production
d	0005198	molecular_function	structural molecule activity
d	0005515	molecular_function	protein binding
d	0005576	cellular_component	extracellular region
d	0005615	cellular_component	extracellular space
d	0005765	cellular_component	lysosomal membrane
d	0005783	cellular_component	endoplasmic reticulum
d	0005788	cellular_component	endoplasmic reticulum lumen
d	0005794	cellular_component	Golgi apparatus
d	0005886	cellular_component	plasma membrane
d	0005925	cellular_component	focal adhesion
d	0006879	biological_process	intracellular iron ion homeostasis
d	0006955	biological_process	immune response
d	0007608	biological_process	sensory perception of smell
d	0007611	biological_process	learning or memory
d	0009897	cellular_component	external side of plasma membrane
d	0009986	cellular_component	cell surface
d	0010038	biological_process	response to metal ion
d	0012507	cellular_component	ER to Golgi transport vesicle membrane
d	0016020	cellular_component	membrane
d	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
d	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
d	0023026	molecular_function	MHC class II protein complex binding
d	0030670	cellular_component	phagocytic vesicle membrane
d	0031901	cellular_component	early endosome membrane
d	0031902	cellular_component	late endosome membrane
d	0031905	cellular_component	early endosome lumen
d	0033572	biological_process	transferrin transport
d	0034756	biological_process	regulation of iron ion transport
d	0034757	biological_process	negative regulation of iron ion transport
d	0035580	cellular_component	specific granule lumen
d	0042605	molecular_function	peptide antigen binding
d	0042612	cellular_component	MHC class I protein complex
d	0042613	cellular_component	MHC class II protein complex
d	0042802	molecular_function	identical protein binding
d	0042803	molecular_function	protein homodimerization activity
d	0042824	cellular_component	MHC class I peptide loading complex
d	0048260	biological_process	positive regulation of receptor-mediated endocytosis
d	0048261	biological_process	negative regulation of receptor-mediated endocytosis
d	0050680	biological_process	negative regulation of epithelial cell proliferation
d	0050768	biological_process	negative regulation of neurogenesis
d	0050778	biological_process	positive regulation of immune response
d	0050870	biological_process	positive regulation of T cell activation
d	0051289	biological_process	protein homotetramerization
d	0055038	cellular_component	recycling endosome membrane
d	0070062	cellular_component	extracellular exosome
d	0071281	biological_process	cellular response to iron ion
d	0071316	biological_process	cellular response to nicotine
d	1904724	cellular_component	tertiary granule lumen
d	1990000	biological_process	amyloid fibril formation
d	1990712	cellular_component	HFE-transferrin receptor complex
d	2000774	biological_process	positive regulation of cellular senescence
d	2000978	biological_process	negative regulation of forebrain neuron differentiation
e	0000139	cellular_component	Golgi membrane
e	0002376	biological_process	immune system process
e	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
e	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
e	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
e	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
e	0002715	biological_process	regulation of natural killer cell mediated immunity
e	0002726	biological_process	positive regulation of T cell cytokine production
e	0005198	molecular_function	structural molecule activity
e	0005515	molecular_function	protein binding
e	0005576	cellular_component	extracellular region
e	0005615	cellular_component	extracellular space
e	0005765	cellular_component	lysosomal membrane
e	0005783	cellular_component	endoplasmic reticulum
e	0005788	cellular_component	endoplasmic reticulum lumen
e	0005794	cellular_component	Golgi apparatus
e	0005886	cellular_component	plasma membrane
e	0005925	cellular_component	focal adhesion
e	0006879	biological_process	intracellular iron ion homeostasis
e	0006955	biological_process	immune response
e	0007608	biological_process	sensory perception of smell
e	0007611	biological_process	learning or memory
e	0009897	cellular_component	external side of plasma membrane
e	0009986	cellular_component	cell surface
e	0010038	biological_process	response to metal ion
e	0012507	cellular_component	ER to Golgi transport vesicle membrane
e	0016020	cellular_component	membrane
e	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
e	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
e	0023026	molecular_function	MHC class II protein complex binding
e	0030670	cellular_component	phagocytic vesicle membrane
e	0031901	cellular_component	early endosome membrane
e	0031902	cellular_component	late endosome membrane
e	0031905	cellular_component	early endosome lumen
e	0033572	biological_process	transferrin transport
e	0034756	biological_process	regulation of iron ion transport
e	0034757	biological_process	negative regulation of iron ion transport
e	0035580	cellular_component	specific granule lumen
e	0042605	molecular_function	peptide antigen binding
e	0042612	cellular_component	MHC class I protein complex
e	0042613	cellular_component	MHC class II protein complex
e	0042802	molecular_function	identical protein binding
e	0042803	molecular_function	protein homodimerization activity
e	0042824	cellular_component	MHC class I peptide loading complex
e	0048260	biological_process	positive regulation of receptor-mediated endocytosis
e	0048261	biological_process	negative regulation of receptor-mediated endocytosis
e	0050680	biological_process	negative regulation of epithelial cell proliferation
e	0050768	biological_process	negative regulation of neurogenesis
e	0050778	biological_process	positive regulation of immune response
e	0050870	biological_process	positive regulation of T cell activation
e	0051289	biological_process	protein homotetramerization
e	0055038	cellular_component	recycling endosome membrane
e	0070062	cellular_component	extracellular exosome
e	0071281	biological_process	cellular response to iron ion
e	0071316	biological_process	cellular response to nicotine
e	1904724	cellular_component	tertiary granule lumen
e	1990000	biological_process	amyloid fibril formation
e	1990712	cellular_component	HFE-transferrin receptor complex
e	2000774	biological_process	positive regulation of cellular senescence
e	2000978	biological_process	negative regulation of forebrain neuron differentiation
f	0000139	cellular_component	Golgi membrane
f	0002376	biological_process	immune system process
f	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
f	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
f	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
f	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
f	0002715	biological_process	regulation of natural killer cell mediated immunity
f	0002726	biological_process	positive regulation of T cell cytokine production
f	0005198	molecular_function	structural molecule activity
f	0005515	molecular_function	protein binding
f	0005576	cellular_component	extracellular region
f	0005615	cellular_component	extracellular space
f	0005765	cellular_component	lysosomal membrane
f	0005783	cellular_component	endoplasmic reticulum
f	0005788	cellular_component	endoplasmic reticulum lumen
f	0005794	cellular_component	Golgi apparatus
f	0005886	cellular_component	plasma membrane
f	0005925	cellular_component	focal adhesion
f	0006879	biological_process	intracellular iron ion homeostasis
f	0006955	biological_process	immune response
f	0007608	biological_process	sensory perception of smell
f	0007611	biological_process	learning or memory
f	0009897	cellular_component	external side of plasma membrane
f	0009986	cellular_component	cell surface
f	0010038	biological_process	response to metal ion
f	0012507	cellular_component	ER to Golgi transport vesicle membrane
f	0016020	cellular_component	membrane
f	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
f	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
f	0023026	molecular_function	MHC class II protein complex binding
f	0030670	cellular_component	phagocytic vesicle membrane
f	0031901	cellular_component	early endosome membrane
f	0031902	cellular_component	late endosome membrane
f	0031905	cellular_component	early endosome lumen
f	0033572	biological_process	transferrin transport
f	0034756	biological_process	regulation of iron ion transport
f	0034757	biological_process	negative regulation of iron ion transport
f	0035580	cellular_component	specific granule lumen
f	0042605	molecular_function	peptide antigen binding
f	0042612	cellular_component	MHC class I protein complex
f	0042613	cellular_component	MHC class II protein complex
f	0042802	molecular_function	identical protein binding
f	0042803	molecular_function	protein homodimerization activity
f	0042824	cellular_component	MHC class I peptide loading complex
f	0048260	biological_process	positive regulation of receptor-mediated endocytosis
f	0048261	biological_process	negative regulation of receptor-mediated endocytosis
f	0050680	biological_process	negative regulation of epithelial cell proliferation
f	0050768	biological_process	negative regulation of neurogenesis
f	0050778	biological_process	positive regulation of immune response
f	0050870	biological_process	positive regulation of T cell activation
f	0051289	biological_process	protein homotetramerization
f	0055038	cellular_component	recycling endosome membrane
f	0070062	cellular_component	extracellular exosome
f	0071281	biological_process	cellular response to iron ion
f	0071316	biological_process	cellular response to nicotine
f	1904724	cellular_component	tertiary granule lumen
f	1990000	biological_process	amyloid fibril formation
f	1990712	cellular_component	HFE-transferrin receptor complex
f	2000774	biological_process	positive regulation of cellular senescence
f	2000978	biological_process	negative regulation of forebrain neuron differentiation
g	0000139	cellular_component	Golgi membrane
g	0002376	biological_process	immune system process
g	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
g	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
g	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
g	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
g	0002715	biological_process	regulation of natural killer cell mediated immunity
g	0002726	biological_process	positive regulation of T cell cytokine production
g	0005198	molecular_function	structural molecule activity
g	0005515	molecular_function	protein binding
g	0005576	cellular_component	extracellular region
g	0005615	cellular_component	extracellular space
g	0005765	cellular_component	lysosomal membrane
g	0005783	cellular_component	endoplasmic reticulum
g	0005788	cellular_component	endoplasmic reticulum lumen
g	0005794	cellular_component	Golgi apparatus
g	0005886	cellular_component	plasma membrane
g	0005925	cellular_component	focal adhesion
g	0006879	biological_process	intracellular iron ion homeostasis
g	0006955	biological_process	immune response
g	0007608	biological_process	sensory perception of smell
g	0007611	biological_process	learning or memory
g	0009897	cellular_component	external side of plasma membrane
g	0009986	cellular_component	cell surface
g	0010038	biological_process	response to metal ion
g	0012507	cellular_component	ER to Golgi transport vesicle membrane
g	0016020	cellular_component	membrane
g	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
g	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
g	0023026	molecular_function	MHC class II protein complex binding
g	0030670	cellular_component	phagocytic vesicle membrane
g	0031901	cellular_component	early endosome membrane
g	0031902	cellular_component	late endosome membrane
g	0031905	cellular_component	early endosome lumen
g	0033572	biological_process	transferrin transport
g	0034756	biological_process	regulation of iron ion transport
g	0034757	biological_process	negative regulation of iron ion transport
g	0035580	cellular_component	specific granule lumen
g	0042605	molecular_function	peptide antigen binding
g	0042612	cellular_component	MHC class I protein complex
g	0042613	cellular_component	MHC class II protein complex
g	0042802	molecular_function	identical protein binding
g	0042803	molecular_function	protein homodimerization activity
g	0042824	cellular_component	MHC class I peptide loading complex
g	0048260	biological_process	positive regulation of receptor-mediated endocytosis
g	0048261	biological_process	negative regulation of receptor-mediated endocytosis
g	0050680	biological_process	negative regulation of epithelial cell proliferation
g	0050768	biological_process	negative regulation of neurogenesis
g	0050778	biological_process	positive regulation of immune response
g	0050870	biological_process	positive regulation of T cell activation
g	0051289	biological_process	protein homotetramerization
g	0055038	cellular_component	recycling endosome membrane
g	0070062	cellular_component	extracellular exosome
g	0071281	biological_process	cellular response to iron ion
g	0071316	biological_process	cellular response to nicotine
g	1904724	cellular_component	tertiary granule lumen
g	1990000	biological_process	amyloid fibril formation
g	1990712	cellular_component	HFE-transferrin receptor complex
g	2000774	biological_process	positive regulation of cellular senescence
g	2000978	biological_process	negative regulation of forebrain neuron differentiation
h	0000139	cellular_component	Golgi membrane
h	0002376	biological_process	immune system process
h	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
h	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
h	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
h	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
h	0002715	biological_process	regulation of natural killer cell mediated immunity
h	0002726	biological_process	positive regulation of T cell cytokine production
h	0005198	molecular_function	structural molecule activity
h	0005515	molecular_function	protein binding
h	0005576	cellular_component	extracellular region
h	0005615	cellular_component	extracellular space
h	0005765	cellular_component	lysosomal membrane
h	0005783	cellular_component	endoplasmic reticulum
h	0005788	cellular_component	endoplasmic reticulum lumen
h	0005794	cellular_component	Golgi apparatus
h	0005886	cellular_component	plasma membrane
h	0005925	cellular_component	focal adhesion
h	0006879	biological_process	intracellular iron ion homeostasis
h	0006955	biological_process	immune response
h	0007608	biological_process	sensory perception of smell
h	0007611	biological_process	learning or memory
h	0009897	cellular_component	external side of plasma membrane
h	0009986	cellular_component	cell surface
h	0010038	biological_process	response to metal ion
h	0012507	cellular_component	ER to Golgi transport vesicle membrane
h	0016020	cellular_component	membrane
h	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
h	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
h	0023026	molecular_function	MHC class II protein complex binding
h	0030670	cellular_component	phagocytic vesicle membrane
h	0031901	cellular_component	early endosome membrane
h	0031902	cellular_component	late endosome membrane
h	0031905	cellular_component	early endosome lumen
h	0033572	biological_process	transferrin transport
h	0034756	biological_process	regulation of iron ion transport
h	0034757	biological_process	negative regulation of iron ion transport
h	0035580	cellular_component	specific granule lumen
h	0042605	molecular_function	peptide antigen binding
h	0042612	cellular_component	MHC class I protein complex
h	0042613	cellular_component	MHC class II protein complex
h	0042802	molecular_function	identical protein binding
h	0042803	molecular_function	protein homodimerization activity
h	0042824	cellular_component	MHC class I peptide loading complex
h	0048260	biological_process	positive regulation of receptor-mediated endocytosis
h	0048261	biological_process	negative regulation of receptor-mediated endocytosis
h	0050680	biological_process	negative regulation of epithelial cell proliferation
h	0050768	biological_process	negative regulation of neurogenesis
h	0050778	biological_process	positive regulation of immune response
h	0050870	biological_process	positive regulation of T cell activation
h	0051289	biological_process	protein homotetramerization
h	0055038	cellular_component	recycling endosome membrane
h	0070062	cellular_component	extracellular exosome
h	0071281	biological_process	cellular response to iron ion
h	0071316	biological_process	cellular response to nicotine
h	1904724	cellular_component	tertiary granule lumen
h	1990000	biological_process	amyloid fibril formation
h	1990712	cellular_component	HFE-transferrin receptor complex
h	2000774	biological_process	positive regulation of cellular senescence
h	2000978	biological_process	negative regulation of forebrain neuron differentiation
i	0000139	cellular_component	Golgi membrane
i	0002376	biological_process	immune system process
i	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
i	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
i	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
i	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
i	0002715	biological_process	regulation of natural killer cell mediated immunity
i	0002726	biological_process	positive regulation of T cell cytokine production
i	0005198	molecular_function	structural molecule activity
i	0005515	molecular_function	protein binding
i	0005576	cellular_component	extracellular region
i	0005615	cellular_component	extracellular space
i	0005765	cellular_component	lysosomal membrane
i	0005783	cellular_component	endoplasmic reticulum
i	0005788	cellular_component	endoplasmic reticulum lumen
i	0005794	cellular_component	Golgi apparatus
i	0005886	cellular_component	plasma membrane
i	0005925	cellular_component	focal adhesion
i	0006879	biological_process	intracellular iron ion homeostasis
i	0006955	biological_process	immune response
i	0007608	biological_process	sensory perception of smell
i	0007611	biological_process	learning or memory
i	0009897	cellular_component	external side of plasma membrane
i	0009986	cellular_component	cell surface
i	0010038	biological_process	response to metal ion
i	0012507	cellular_component	ER to Golgi transport vesicle membrane
i	0016020	cellular_component	membrane
i	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
i	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
i	0023026	molecular_function	MHC class II protein complex binding
i	0030670	cellular_component	phagocytic vesicle membrane
i	0031901	cellular_component	early endosome membrane
i	0031902	cellular_component	late endosome membrane
i	0031905	cellular_component	early endosome lumen
i	0033572	biological_process	transferrin transport
i	0034756	biological_process	regulation of iron ion transport
i	0034757	biological_process	negative regulation of iron ion transport
i	0035580	cellular_component	specific granule lumen
i	0042605	molecular_function	peptide antigen binding
i	0042612	cellular_component	MHC class I protein complex
i	0042613	cellular_component	MHC class II protein complex
i	0042802	molecular_function	identical protein binding
i	0042803	molecular_function	protein homodimerization activity
i	0042824	cellular_component	MHC class I peptide loading complex
i	0048260	biological_process	positive regulation of receptor-mediated endocytosis
i	0048261	biological_process	negative regulation of receptor-mediated endocytosis
i	0050680	biological_process	negative regulation of epithelial cell proliferation
i	0050768	biological_process	negative regulation of neurogenesis
i	0050778	biological_process	positive regulation of immune response
i	0050870	biological_process	positive regulation of T cell activation
i	0051289	biological_process	protein homotetramerization
i	0055038	cellular_component	recycling endosome membrane
i	0070062	cellular_component	extracellular exosome
i	0071281	biological_process	cellular response to iron ion
i	0071316	biological_process	cellular response to nicotine
i	1904724	cellular_component	tertiary granule lumen
i	1990000	biological_process	amyloid fibril formation
i	1990712	cellular_component	HFE-transferrin receptor complex
i	2000774	biological_process	positive regulation of cellular senescence
i	2000978	biological_process	negative regulation of forebrain neuron differentiation
j	0000139	cellular_component	Golgi membrane
j	0002376	biological_process	immune system process
j	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
j	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
j	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
j	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
j	0002715	biological_process	regulation of natural killer cell mediated immunity
j	0002726	biological_process	positive regulation of T cell cytokine production
j	0005198	molecular_function	structural molecule activity
j	0005515	molecular_function	protein binding
j	0005576	cellular_component	extracellular region
j	0005615	cellular_component	extracellular space
j	0005765	cellular_component	lysosomal membrane
j	0005783	cellular_component	endoplasmic reticulum
j	0005788	cellular_component	endoplasmic reticulum lumen
j	0005794	cellular_component	Golgi apparatus
j	0005886	cellular_component	plasma membrane
j	0005925	cellular_component	focal adhesion
j	0006879	biological_process	intracellular iron ion homeostasis
j	0006955	biological_process	immune response
j	0007608	biological_process	sensory perception of smell
j	0007611	biological_process	learning or memory
j	0009897	cellular_component	external side of plasma membrane
j	0009986	cellular_component	cell surface
j	0010038	biological_process	response to metal ion
j	0012507	cellular_component	ER to Golgi transport vesicle membrane
j	0016020	cellular_component	membrane
j	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
j	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
j	0023026	molecular_function	MHC class II protein complex binding
j	0030670	cellular_component	phagocytic vesicle membrane
j	0031901	cellular_component	early endosome membrane
j	0031902	cellular_component	late endosome membrane
j	0031905	cellular_component	early endosome lumen
j	0033572	biological_process	transferrin transport
j	0034756	biological_process	regulation of iron ion transport
j	0034757	biological_process	negative regulation of iron ion transport
j	0035580	cellular_component	specific granule lumen
j	0042605	molecular_function	peptide antigen binding
j	0042612	cellular_component	MHC class I protein complex
j	0042613	cellular_component	MHC class II protein complex
j	0042802	molecular_function	identical protein binding
j	0042803	molecular_function	protein homodimerization activity
j	0042824	cellular_component	MHC class I peptide loading complex
j	0048260	biological_process	positive regulation of receptor-mediated endocytosis
j	0048261	biological_process	negative regulation of receptor-mediated endocytosis
j	0050680	biological_process	negative regulation of epithelial cell proliferation
j	0050768	biological_process	negative regulation of neurogenesis
j	0050778	biological_process	positive regulation of immune response
j	0050870	biological_process	positive regulation of T cell activation
j	0051289	biological_process	protein homotetramerization
j	0055038	cellular_component	recycling endosome membrane
j	0070062	cellular_component	extracellular exosome
j	0071281	biological_process	cellular response to iron ion
j	0071316	biological_process	cellular response to nicotine
j	1904724	cellular_component	tertiary granule lumen
j	1990000	biological_process	amyloid fibril formation
j	1990712	cellular_component	HFE-transferrin receptor complex
j	2000774	biological_process	positive regulation of cellular senescence
j	2000978	biological_process	negative regulation of forebrain neuron differentiation
k	0000139	cellular_component	Golgi membrane
k	0002376	biological_process	immune system process
k	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
k	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
k	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
k	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
k	0002715	biological_process	regulation of natural killer cell mediated immunity
k	0002726	biological_process	positive regulation of T cell cytokine production
k	0005198	molecular_function	structural molecule activity
k	0005515	molecular_function	protein binding
k	0005576	cellular_component	extracellular region
k	0005615	cellular_component	extracellular space
k	0005765	cellular_component	lysosomal membrane
k	0005783	cellular_component	endoplasmic reticulum
k	0005788	cellular_component	endoplasmic reticulum lumen
k	0005794	cellular_component	Golgi apparatus
k	0005886	cellular_component	plasma membrane
k	0005925	cellular_component	focal adhesion
k	0006879	biological_process	intracellular iron ion homeostasis
k	0006955	biological_process	immune response
k	0007608	biological_process	sensory perception of smell
k	0007611	biological_process	learning or memory
k	0009897	cellular_component	external side of plasma membrane
k	0009986	cellular_component	cell surface
k	0010038	biological_process	response to metal ion
k	0012507	cellular_component	ER to Golgi transport vesicle membrane
k	0016020	cellular_component	membrane
k	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
k	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
k	0023026	molecular_function	MHC class II protein complex binding
k	0030670	cellular_component	phagocytic vesicle membrane
k	0031901	cellular_component	early endosome membrane
k	0031902	cellular_component	late endosome membrane
k	0031905	cellular_component	early endosome lumen
k	0033572	biological_process	transferrin transport
k	0034756	biological_process	regulation of iron ion transport
k	0034757	biological_process	negative regulation of iron ion transport
k	0035580	cellular_component	specific granule lumen
k	0042605	molecular_function	peptide antigen binding
k	0042612	cellular_component	MHC class I protein complex
k	0042613	cellular_component	MHC class II protein complex
k	0042802	molecular_function	identical protein binding
k	0042803	molecular_function	protein homodimerization activity
k	0042824	cellular_component	MHC class I peptide loading complex
k	0048260	biological_process	positive regulation of receptor-mediated endocytosis
k	0048261	biological_process	negative regulation of receptor-mediated endocytosis
k	0050680	biological_process	negative regulation of epithelial cell proliferation
k	0050768	biological_process	negative regulation of neurogenesis
k	0050778	biological_process	positive regulation of immune response
k	0050870	biological_process	positive regulation of T cell activation
k	0051289	biological_process	protein homotetramerization
k	0055038	cellular_component	recycling endosome membrane
k	0070062	cellular_component	extracellular exosome
k	0071281	biological_process	cellular response to iron ion
k	0071316	biological_process	cellular response to nicotine
k	1904724	cellular_component	tertiary granule lumen
k	1990000	biological_process	amyloid fibril formation
k	1990712	cellular_component	HFE-transferrin receptor complex
k	2000774	biological_process	positive regulation of cellular senescence
k	2000978	biological_process	negative regulation of forebrain neuron differentiation
l	0000139	cellular_component	Golgi membrane
l	0002376	biological_process	immune system process
l	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
l	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
l	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
l	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
l	0002715	biological_process	regulation of natural killer cell mediated immunity
l	0002726	biological_process	positive regulation of T cell cytokine production
l	0005198	molecular_function	structural molecule activity
l	0005515	molecular_function	protein binding
l	0005576	cellular_component	extracellular region
l	0005615	cellular_component	extracellular space
l	0005765	cellular_component	lysosomal membrane
l	0005783	cellular_component	endoplasmic reticulum
l	0005788	cellular_component	endoplasmic reticulum lumen
l	0005794	cellular_component	Golgi apparatus
l	0005886	cellular_component	plasma membrane
l	0005925	cellular_component	focal adhesion
l	0006879	biological_process	intracellular iron ion homeostasis
l	0006955	biological_process	immune response
l	0007608	biological_process	sensory perception of smell
l	0007611	biological_process	learning or memory
l	0009897	cellular_component	external side of plasma membrane
l	0009986	cellular_component	cell surface
l	0010038	biological_process	response to metal ion
l	0012507	cellular_component	ER to Golgi transport vesicle membrane
l	0016020	cellular_component	membrane
l	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
l	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
l	0023026	molecular_function	MHC class II protein complex binding
l	0030670	cellular_component	phagocytic vesicle membrane
l	0031901	cellular_component	early endosome membrane
l	0031902	cellular_component	late endosome membrane
l	0031905	cellular_component	early endosome lumen
l	0033572	biological_process	transferrin transport
l	0034756	biological_process	regulation of iron ion transport
l	0034757	biological_process	negative regulation of iron ion transport
l	0035580	cellular_component	specific granule lumen
l	0042605	molecular_function	peptide antigen binding
l	0042612	cellular_component	MHC class I protein complex
l	0042613	cellular_component	MHC class II protein complex
l	0042802	molecular_function	identical protein binding
l	0042803	molecular_function	protein homodimerization activity
l	0042824	cellular_component	MHC class I peptide loading complex
l	0048260	biological_process	positive regulation of receptor-mediated endocytosis
l	0048261	biological_process	negative regulation of receptor-mediated endocytosis
l	0050680	biological_process	negative regulation of epithelial cell proliferation
l	0050768	biological_process	negative regulation of neurogenesis
l	0050778	biological_process	positive regulation of immune response
l	0050870	biological_process	positive regulation of T cell activation
l	0051289	biological_process	protein homotetramerization
l	0055038	cellular_component	recycling endosome membrane
l	0070062	cellular_component	extracellular exosome
l	0071281	biological_process	cellular response to iron ion
l	0071316	biological_process	cellular response to nicotine
l	1904724	cellular_component	tertiary granule lumen
l	1990000	biological_process	amyloid fibril formation
l	1990712	cellular_component	HFE-transferrin receptor complex
l	2000774	biological_process	positive regulation of cellular senescence
l	2000978	biological_process	negative regulation of forebrain neuron differentiation
m	0000139	cellular_component	Golgi membrane
m	0002376	biological_process	immune system process
m	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
m	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
m	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
m	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
m	0002715	biological_process	regulation of natural killer cell mediated immunity
m	0002726	biological_process	positive regulation of T cell cytokine production
m	0005198	molecular_function	structural molecule activity
m	0005515	molecular_function	protein binding
m	0005576	cellular_component	extracellular region
m	0005615	cellular_component	extracellular space
m	0005765	cellular_component	lysosomal membrane
m	0005783	cellular_component	endoplasmic reticulum
m	0005788	cellular_component	endoplasmic reticulum lumen
m	0005794	cellular_component	Golgi apparatus
m	0005886	cellular_component	plasma membrane
m	0005925	cellular_component	focal adhesion
m	0006879	biological_process	intracellular iron ion homeostasis
m	0006955	biological_process	immune response
m	0007608	biological_process	sensory perception of smell
m	0007611	biological_process	learning or memory
m	0009897	cellular_component	external side of plasma membrane
m	0009986	cellular_component	cell surface
m	0010038	biological_process	response to metal ion
m	0012507	cellular_component	ER to Golgi transport vesicle membrane
m	0016020	cellular_component	membrane
m	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
m	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
m	0023026	molecular_function	MHC class II protein complex binding
m	0030670	cellular_component	phagocytic vesicle membrane
m	0031901	cellular_component	early endosome membrane
m	0031902	cellular_component	late endosome membrane
m	0031905	cellular_component	early endosome lumen
m	0033572	biological_process	transferrin transport
m	0034756	biological_process	regulation of iron ion transport
m	0034757	biological_process	negative regulation of iron ion transport
m	0035580	cellular_component	specific granule lumen
m	0042605	molecular_function	peptide antigen binding
m	0042612	cellular_component	MHC class I protein complex
m	0042613	cellular_component	MHC class II protein complex
m	0042802	molecular_function	identical protein binding
m	0042803	molecular_function	protein homodimerization activity
m	0042824	cellular_component	MHC class I peptide loading complex
m	0048260	biological_process	positive regulation of receptor-mediated endocytosis
m	0048261	biological_process	negative regulation of receptor-mediated endocytosis
m	0050680	biological_process	negative regulation of epithelial cell proliferation
m	0050768	biological_process	negative regulation of neurogenesis
m	0050778	biological_process	positive regulation of immune response
m	0050870	biological_process	positive regulation of T cell activation
m	0051289	biological_process	protein homotetramerization
m	0055038	cellular_component	recycling endosome membrane
m	0070062	cellular_component	extracellular exosome
m	0071281	biological_process	cellular response to iron ion
m	0071316	biological_process	cellular response to nicotine
m	1904724	cellular_component	tertiary granule lumen
m	1990000	biological_process	amyloid fibril formation
m	1990712	cellular_component	HFE-transferrin receptor complex
m	2000774	biological_process	positive regulation of cellular senescence
m	2000978	biological_process	negative regulation of forebrain neuron differentiation
n	0000139	cellular_component	Golgi membrane
n	0002376	biological_process	immune system process
n	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
n	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
n	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
n	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
n	0002715	biological_process	regulation of natural killer cell mediated immunity
n	0002726	biological_process	positive regulation of T cell cytokine production
n	0005198	molecular_function	structural molecule activity
n	0005515	molecular_function	protein binding
n	0005576	cellular_component	extracellular region
n	0005615	cellular_component	extracellular space
n	0005765	cellular_component	lysosomal membrane
n	0005783	cellular_component	endoplasmic reticulum
n	0005788	cellular_component	endoplasmic reticulum lumen
n	0005794	cellular_component	Golgi apparatus
n	0005886	cellular_component	plasma membrane
n	0005925	cellular_component	focal adhesion
n	0006879	biological_process	intracellular iron ion homeostasis
n	0006955	biological_process	immune response
n	0007608	biological_process	sensory perception of smell
n	0007611	biological_process	learning or memory
n	0009897	cellular_component	external side of plasma membrane
n	0009986	cellular_component	cell surface
n	0010038	biological_process	response to metal ion
n	0012507	cellular_component	ER to Golgi transport vesicle membrane
n	0016020	cellular_component	membrane
n	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
n	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
n	0023026	molecular_function	MHC class II protein complex binding
n	0030670	cellular_component	phagocytic vesicle membrane
n	0031901	cellular_component	early endosome membrane
n	0031902	cellular_component	late endosome membrane
n	0031905	cellular_component	early endosome lumen
n	0033572	biological_process	transferrin transport
n	0034756	biological_process	regulation of iron ion transport
n	0034757	biological_process	negative regulation of iron ion transport
n	0035580	cellular_component	specific granule lumen
n	0042605	molecular_function	peptide antigen binding
n	0042612	cellular_component	MHC class I protein complex
n	0042613	cellular_component	MHC class II protein complex
n	0042802	molecular_function	identical protein binding
n	0042803	molecular_function	protein homodimerization activity
n	0042824	cellular_component	MHC class I peptide loading complex
n	0048260	biological_process	positive regulation of receptor-mediated endocytosis
n	0048261	biological_process	negative regulation of receptor-mediated endocytosis
n	0050680	biological_process	negative regulation of epithelial cell proliferation
n	0050768	biological_process	negative regulation of neurogenesis
n	0050778	biological_process	positive regulation of immune response
n	0050870	biological_process	positive regulation of T cell activation
n	0051289	biological_process	protein homotetramerization
n	0055038	cellular_component	recycling endosome membrane
n	0070062	cellular_component	extracellular exosome
n	0071281	biological_process	cellular response to iron ion
n	0071316	biological_process	cellular response to nicotine
n	1904724	cellular_component	tertiary granule lumen
n	1990000	biological_process	amyloid fibril formation
n	1990712	cellular_component	HFE-transferrin receptor complex
n	2000774	biological_process	positive regulation of cellular senescence
n	2000978	biological_process	negative regulation of forebrain neuron differentiation
o	0000139	cellular_component	Golgi membrane
o	0002376	biological_process	immune system process
o	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
o	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
o	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
o	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
o	0002715	biological_process	regulation of natural killer cell mediated immunity
o	0002726	biological_process	positive regulation of T cell cytokine production
o	0005198	molecular_function	structural molecule activity
o	0005515	molecular_function	protein binding
o	0005576	cellular_component	extracellular region
o	0005615	cellular_component	extracellular space
o	0005765	cellular_component	lysosomal membrane
o	0005783	cellular_component	endoplasmic reticulum
o	0005788	cellular_component	endoplasmic reticulum lumen
o	0005794	cellular_component	Golgi apparatus
o	0005886	cellular_component	plasma membrane
o	0005925	cellular_component	focal adhesion
o	0006879	biological_process	intracellular iron ion homeostasis
o	0006955	biological_process	immune response
o	0007608	biological_process	sensory perception of smell
o	0007611	biological_process	learning or memory
o	0009897	cellular_component	external side of plasma membrane
o	0009986	cellular_component	cell surface
o	0010038	biological_process	response to metal ion
o	0012507	cellular_component	ER to Golgi transport vesicle membrane
o	0016020	cellular_component	membrane
o	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
o	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
o	0023026	molecular_function	MHC class II protein complex binding
o	0030670	cellular_component	phagocytic vesicle membrane
o	0031901	cellular_component	early endosome membrane
o	0031902	cellular_component	late endosome membrane
o	0031905	cellular_component	early endosome lumen
o	0033572	biological_process	transferrin transport
o	0034756	biological_process	regulation of iron ion transport
o	0034757	biological_process	negative regulation of iron ion transport
o	0035580	cellular_component	specific granule lumen
o	0042605	molecular_function	peptide antigen binding
o	0042612	cellular_component	MHC class I protein complex
o	0042613	cellular_component	MHC class II protein complex
o	0042802	molecular_function	identical protein binding
o	0042803	molecular_function	protein homodimerization activity
o	0042824	cellular_component	MHC class I peptide loading complex
o	0048260	biological_process	positive regulation of receptor-mediated endocytosis
o	0048261	biological_process	negative regulation of receptor-mediated endocytosis
o	0050680	biological_process	negative regulation of epithelial cell proliferation
o	0050768	biological_process	negative regulation of neurogenesis
o	0050778	biological_process	positive regulation of immune response
o	0050870	biological_process	positive regulation of T cell activation
o	0051289	biological_process	protein homotetramerization
o	0055038	cellular_component	recycling endosome membrane
o	0070062	cellular_component	extracellular exosome
o	0071281	biological_process	cellular response to iron ion
o	0071316	biological_process	cellular response to nicotine
o	1904724	cellular_component	tertiary granule lumen
o	1990000	biological_process	amyloid fibril formation
o	1990712	cellular_component	HFE-transferrin receptor complex
o	2000774	biological_process	positive regulation of cellular senescence
o	2000978	biological_process	negative regulation of forebrain neuron differentiation
p	0000139	cellular_component	Golgi membrane
p	0002376	biological_process	immune system process
p	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
p	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
p	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
p	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
p	0002715	biological_process	regulation of natural killer cell mediated immunity
p	0002726	biological_process	positive regulation of T cell cytokine production
p	0005198	molecular_function	structural molecule activity
p	0005515	molecular_function	protein binding
p	0005576	cellular_component	extracellular region
p	0005615	cellular_component	extracellular space
p	0005765	cellular_component	lysosomal membrane
p	0005783	cellular_component	endoplasmic reticulum
p	0005788	cellular_component	endoplasmic reticulum lumen
p	0005794	cellular_component	Golgi apparatus
p	0005886	cellular_component	plasma membrane
p	0005925	cellular_component	focal adhesion
p	0006879	biological_process	intracellular iron ion homeostasis
p	0006955	biological_process	immune response
p	0007608	biological_process	sensory perception of smell
p	0007611	biological_process	learning or memory
p	0009897	cellular_component	external side of plasma membrane
p	0009986	cellular_component	cell surface
p	0010038	biological_process	response to metal ion
p	0012507	cellular_component	ER to Golgi transport vesicle membrane
p	0016020	cellular_component	membrane
p	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
p	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
p	0023026	molecular_function	MHC class II protein complex binding
p	0030670	cellular_component	phagocytic vesicle membrane
p	0031901	cellular_component	early endosome membrane
p	0031902	cellular_component	late endosome membrane
p	0031905	cellular_component	early endosome lumen
p	0033572	biological_process	transferrin transport
p	0034756	biological_process	regulation of iron ion transport
p	0034757	biological_process	negative regulation of iron ion transport
p	0035580	cellular_component	specific granule lumen
p	0042605	molecular_function	peptide antigen binding
p	0042612	cellular_component	MHC class I protein complex
p	0042613	cellular_component	MHC class II protein complex
p	0042802	molecular_function	identical protein binding
p	0042803	molecular_function	protein homodimerization activity
p	0042824	cellular_component	MHC class I peptide loading complex
p	0048260	biological_process	positive regulation of receptor-mediated endocytosis
p	0048261	biological_process	negative regulation of receptor-mediated endocytosis
p	0050680	biological_process	negative regulation of epithelial cell proliferation
p	0050768	biological_process	negative regulation of neurogenesis
p	0050778	biological_process	positive regulation of immune response
p	0050870	biological_process	positive regulation of T cell activation
p	0051289	biological_process	protein homotetramerization
p	0055038	cellular_component	recycling endosome membrane
p	0070062	cellular_component	extracellular exosome
p	0071281	biological_process	cellular response to iron ion
p	0071316	biological_process	cellular response to nicotine
p	1904724	cellular_component	tertiary granule lumen
p	1990000	biological_process	amyloid fibril formation
p	1990712	cellular_component	HFE-transferrin receptor complex
p	2000774	biological_process	positive regulation of cellular senescence
p	2000978	biological_process	negative regulation of forebrain neuron differentiation
q	0000139	cellular_component	Golgi membrane
q	0002376	biological_process	immune system process
q	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
q	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
q	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
q	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
q	0002715	biological_process	regulation of natural killer cell mediated immunity
q	0002726	biological_process	positive regulation of T cell cytokine production
q	0005198	molecular_function	structural molecule activity
q	0005515	molecular_function	protein binding
q	0005576	cellular_component	extracellular region
q	0005615	cellular_component	extracellular space
q	0005765	cellular_component	lysosomal membrane
q	0005783	cellular_component	endoplasmic reticulum
q	0005788	cellular_component	endoplasmic reticulum lumen
q	0005794	cellular_component	Golgi apparatus
q	0005886	cellular_component	plasma membrane
q	0005925	cellular_component	focal adhesion
q	0006879	biological_process	intracellular iron ion homeostasis
q	0006955	biological_process	immune response
q	0007608	biological_process	sensory perception of smell
q	0007611	biological_process	learning or memory
q	0009897	cellular_component	external side of plasma membrane
q	0009986	cellular_component	cell surface
q	0010038	biological_process	response to metal ion
q	0012507	cellular_component	ER to Golgi transport vesicle membrane
q	0016020	cellular_component	membrane
q	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
q	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
q	0023026	molecular_function	MHC class II protein complex binding
q	0030670	cellular_component	phagocytic vesicle membrane
q	0031901	cellular_component	early endosome membrane
q	0031902	cellular_component	late endosome membrane
q	0031905	cellular_component	early endosome lumen
q	0033572	biological_process	transferrin transport
q	0034756	biological_process	regulation of iron ion transport
q	0034757	biological_process	negative regulation of iron ion transport
q	0035580	cellular_component	specific granule lumen
q	0042605	molecular_function	peptide antigen binding
q	0042612	cellular_component	MHC class I protein complex
q	0042613	cellular_component	MHC class II protein complex
q	0042802	molecular_function	identical protein binding
q	0042803	molecular_function	protein homodimerization activity
q	0042824	cellular_component	MHC class I peptide loading complex
q	0048260	biological_process	positive regulation of receptor-mediated endocytosis
q	0048261	biological_process	negative regulation of receptor-mediated endocytosis
q	0050680	biological_process	negative regulation of epithelial cell proliferation
q	0050768	biological_process	negative regulation of neurogenesis
q	0050778	biological_process	positive regulation of immune response
q	0050870	biological_process	positive regulation of T cell activation
q	0051289	biological_process	protein homotetramerization
q	0055038	cellular_component	recycling endosome membrane
q	0070062	cellular_component	extracellular exosome
q	0071281	biological_process	cellular response to iron ion
q	0071316	biological_process	cellular response to nicotine
q	1904724	cellular_component	tertiary granule lumen
q	1990000	biological_process	amyloid fibril formation
q	1990712	cellular_component	HFE-transferrin receptor complex
q	2000774	biological_process	positive regulation of cellular senescence
q	2000978	biological_process	negative regulation of forebrain neuron differentiation
r	0000139	cellular_component	Golgi membrane
r	0002376	biological_process	immune system process
r	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
r	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
r	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
r	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
r	0002715	biological_process	regulation of natural killer cell mediated immunity
r	0002726	biological_process	positive regulation of T cell cytokine production
r	0005198	molecular_function	structural molecule activity
r	0005515	molecular_function	protein binding
r	0005576	cellular_component	extracellular region
r	0005615	cellular_component	extracellular space
r	0005765	cellular_component	lysosomal membrane
r	0005783	cellular_component	endoplasmic reticulum
r	0005788	cellular_component	endoplasmic reticulum lumen
r	0005794	cellular_component	Golgi apparatus
r	0005886	cellular_component	plasma membrane
r	0005925	cellular_component	focal adhesion
r	0006879	biological_process	intracellular iron ion homeostasis
r	0006955	biological_process	immune response
r	0007608	biological_process	sensory perception of smell
r	0007611	biological_process	learning or memory
r	0009897	cellular_component	external side of plasma membrane
r	0009986	cellular_component	cell surface
r	0010038	biological_process	response to metal ion
r	0012507	cellular_component	ER to Golgi transport vesicle membrane
r	0016020	cellular_component	membrane
r	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
r	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
r	0023026	molecular_function	MHC class II protein complex binding
r	0030670	cellular_component	phagocytic vesicle membrane
r	0031901	cellular_component	early endosome membrane
r	0031902	cellular_component	late endosome membrane
r	0031905	cellular_component	early endosome lumen
r	0033572	biological_process	transferrin transport
r	0034756	biological_process	regulation of iron ion transport
r	0034757	biological_process	negative regulation of iron ion transport
r	0035580	cellular_component	specific granule lumen
r	0042605	molecular_function	peptide antigen binding
r	0042612	cellular_component	MHC class I protein complex
r	0042613	cellular_component	MHC class II protein complex
r	0042802	molecular_function	identical protein binding
r	0042803	molecular_function	protein homodimerization activity
r	0042824	cellular_component	MHC class I peptide loading complex
r	0048260	biological_process	positive regulation of receptor-mediated endocytosis
r	0048261	biological_process	negative regulation of receptor-mediated endocytosis
r	0050680	biological_process	negative regulation of epithelial cell proliferation
r	0050768	biological_process	negative regulation of neurogenesis
r	0050778	biological_process	positive regulation of immune response
r	0050870	biological_process	positive regulation of T cell activation
r	0051289	biological_process	protein homotetramerization
r	0055038	cellular_component	recycling endosome membrane
r	0070062	cellular_component	extracellular exosome
r	0071281	biological_process	cellular response to iron ion
r	0071316	biological_process	cellular response to nicotine
r	1904724	cellular_component	tertiary granule lumen
r	1990000	biological_process	amyloid fibril formation
r	1990712	cellular_component	HFE-transferrin receptor complex
r	2000774	biological_process	positive regulation of cellular senescence
r	2000978	biological_process	negative regulation of forebrain neuron differentiation
s	0000139	cellular_component	Golgi membrane
s	0002376	biological_process	immune system process
s	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
s	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
s	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
s	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
s	0002715	biological_process	regulation of natural killer cell mediated immunity
s	0002726	biological_process	positive regulation of T cell cytokine production
s	0005198	molecular_function	structural molecule activity
s	0005515	molecular_function	protein binding
s	0005576	cellular_component	extracellular region
s	0005615	cellular_component	extracellular space
s	0005765	cellular_component	lysosomal membrane
s	0005783	cellular_component	endoplasmic reticulum
s	0005788	cellular_component	endoplasmic reticulum lumen
s	0005794	cellular_component	Golgi apparatus
s	0005886	cellular_component	plasma membrane
s	0005925	cellular_component	focal adhesion
s	0006879	biological_process	intracellular iron ion homeostasis
s	0006955	biological_process	immune response
s	0007608	biological_process	sensory perception of smell
s	0007611	biological_process	learning or memory
s	0009897	cellular_component	external side of plasma membrane
s	0009986	cellular_component	cell surface
s	0010038	biological_process	response to metal ion
s	0012507	cellular_component	ER to Golgi transport vesicle membrane
s	0016020	cellular_component	membrane
s	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
s	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
s	0023026	molecular_function	MHC class II protein complex binding
s	0030670	cellular_component	phagocytic vesicle membrane
s	0031901	cellular_component	early endosome membrane
s	0031902	cellular_component	late endosome membrane
s	0031905	cellular_component	early endosome lumen
s	0033572	biological_process	transferrin transport
s	0034756	biological_process	regulation of iron ion transport
s	0034757	biological_process	negative regulation of iron ion transport
s	0035580	cellular_component	specific granule lumen
s	0042605	molecular_function	peptide antigen binding
s	0042612	cellular_component	MHC class I protein complex
s	0042613	cellular_component	MHC class II protein complex
s	0042802	molecular_function	identical protein binding
s	0042803	molecular_function	protein homodimerization activity
s	0042824	cellular_component	MHC class I peptide loading complex
s	0048260	biological_process	positive regulation of receptor-mediated endocytosis
s	0048261	biological_process	negative regulation of receptor-mediated endocytosis
s	0050680	biological_process	negative regulation of epithelial cell proliferation
s	0050768	biological_process	negative regulation of neurogenesis
s	0050778	biological_process	positive regulation of immune response
s	0050870	biological_process	positive regulation of T cell activation
s	0051289	biological_process	protein homotetramerization
s	0055038	cellular_component	recycling endosome membrane
s	0070062	cellular_component	extracellular exosome
s	0071281	biological_process	cellular response to iron ion
s	0071316	biological_process	cellular response to nicotine
s	1904724	cellular_component	tertiary granule lumen
s	1990000	biological_process	amyloid fibril formation
s	1990712	cellular_component	HFE-transferrin receptor complex
s	2000774	biological_process	positive regulation of cellular senescence
s	2000978	biological_process	negative regulation of forebrain neuron differentiation
t	0000139	cellular_component	Golgi membrane
t	0002376	biological_process	immune system process
t	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
t	0002477	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class Ib
t	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
t	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
t	0002715	biological_process	regulation of natural killer cell mediated immunity
t	0002726	biological_process	positive regulation of T cell cytokine production
t	0005198	molecular_function	structural molecule activity
t	0005515	molecular_function	protein binding
t	0005576	cellular_component	extracellular region
t	0005615	cellular_component	extracellular space
t	0005765	cellular_component	lysosomal membrane
t	0005783	cellular_component	endoplasmic reticulum
t	0005788	cellular_component	endoplasmic reticulum lumen
t	0005794	cellular_component	Golgi apparatus
t	0005886	cellular_component	plasma membrane
t	0005925	cellular_component	focal adhesion
t	0006879	biological_process	intracellular iron ion homeostasis
t	0006955	biological_process	immune response
t	0007608	biological_process	sensory perception of smell
t	0007611	biological_process	learning or memory
t	0009897	cellular_component	external side of plasma membrane
t	0009986	cellular_component	cell surface
t	0010038	biological_process	response to metal ion
t	0012507	cellular_component	ER to Golgi transport vesicle membrane
t	0016020	cellular_component	membrane
t	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
t	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
t	0023026	molecular_function	MHC class II protein complex binding
t	0030670	cellular_component	phagocytic vesicle membrane
t	0031901	cellular_component	early endosome membrane
t	0031902	cellular_component	late endosome membrane
t	0031905	cellular_component	early endosome lumen
t	0033572	biological_process	transferrin transport
t	0034756	biological_process	regulation of iron ion transport
t	0034757	biological_process	negative regulation of iron ion transport
t	0035580	cellular_component	specific granule lumen
t	0042605	molecular_function	peptide antigen binding
t	0042612	cellular_component	MHC class I protein complex
t	0042613	cellular_component	MHC class II protein complex
t	0042802	molecular_function	identical protein binding
t	0042803	molecular_function	protein homodimerization activity
t	0042824	cellular_component	MHC class I peptide loading complex
t	0048260	biological_process	positive regulation of receptor-mediated endocytosis
t	0048261	biological_process	negative regulation of receptor-mediated endocytosis
t	0050680	biological_process	negative regulation of epithelial cell proliferation
t	0050768	biological_process	negative regulation of neurogenesis
t	0050778	biological_process	positive regulation of immune response
t	0050870	biological_process	positive regulation of T cell activation
t	0051289	biological_process	protein homotetramerization
t	0055038	cellular_component	recycling endosome membrane
t	0070062	cellular_component	extracellular exosome
t	0071281	biological_process	cellular response to iron ion
t	0071316	biological_process	cellular response to nicotine
t	1904724	cellular_component	tertiary granule lumen
t	1990000	biological_process	amyloid fibril formation
t	1990712	cellular_component	HFE-transferrin receptor complex
t	2000774	biological_process	positive regulation of cellular senescence
t	2000978	biological_process	negative regulation of forebrain neuron differentiation

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCHVQH

Chain	Residue	Details
R	TYR257-HIS263
d	TYR79-HIS85

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1720
Details	Domain: {"description":"Ig-like C1-type","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1780
Details	Region: {"description":"Alpha-1","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1820
Details	Region: {"description":"Alpha-2","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1820
Details	Region: {"description":"Alpha-3","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	120
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21943705","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	40
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21543847","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	20
Details	Modified residue: {"description":"Sulfotyrosine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	20
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1760
Details	Domain: {"description":"Ig-like C1-type"}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	20
Details	Modified residue: {"description":"Pyrrolidone carboxylic acid; in form pI 5.3","evidences":[{"source":"PubMed","id":"7554280","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	20
Details	Glycosylation: {"description":"N-linked (Glc) (glycation) isoleucine; in hemodialysis-associated amyloidosis","evidences":[{"source":"PubMed","id":"7918443","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	120
Details	Glycosylation: {"description":"N-linked (Glc) (glycation) lysine; in vitro","evidences":[{"source":"PubMed","id":"7918443","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---