6N9Q

Structure of the Quorum Quenching lactonase from Parageobacillus caldoxylosilyticus bind to substrate C4-AHL

Functional Information from GO Data

Chain	GOid	namespace	contents
D	0016787	molecular_function	hydrolase activity
D	0046872	molecular_function	metal ion binding
P	0016787	molecular_function	hydrolase activity
P	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue CO P 301

Chain	Residue
P	HIS118
P	HIS120
P	HIS198
P	ASP220
P	HL4304
P	FE314
P	HOH401

---

site_id	AC2
Number of Residues	4
Details	binding site for residue SO4 P 302

Chain	Residue
P	ARG253
P	PGE316
P	ASN182
P	ARG250

---

site_id	AC3
Number of Residues	5
Details	binding site for residue SO4 P 303

Chain	Residue
P	GLU109
P	ASP110
P	ILE111
P	ARG112
P	ASN132

---

site_id	AC4
Number of Residues	14
Details	binding site for residue HL4 P 304

Chain	Residue
P	MET20
P	MET22
P	PHE48
P	PHE87
P	HIS120
P	ASP122
P	ALA157
P	HIS198
P	ASP220
P	TYR223
P	HIS266
P	CO301
P	FE314
P	HOH401

---

site_id	AC5
Number of Residues	4
Details	binding site for residue EDO P 305

Chain	Residue
P	GLN261
P	VAL262
P	PHE264
P	EDO309

---

site_id	AC6
Number of Residues	2
Details	binding site for residue EDO P 306

Chain	Residue
P	THR131
P	THR134

---

site_id	AC7
Number of Residues	1
Details	binding site for residue EDO P 308

Chain	Residue
P	PRO210

---

site_id	AC8
Number of Residues	4
Details	binding site for residue EDO P 309

Chain	Residue
P	GLN261
P	TRP263
P	GLN270
P	EDO305

---

site_id	AC9
Number of Residues	5
Details	binding site for residue EDO P 310

Chain	Residue
P	PRO70
P	SER72
P	MET73
P	TRP89
P	TYR96

---

site_id	AD1
Number of Residues	5
Details	binding site for residue EDO P 311

Chain	Residue
D	ARG151
P	TRP173
P	ARG174
P	THR175
P	LYS177

---

site_id	AD2
Number of Residues	11
Details	binding site for residue 1PE P 312

Chain	Residue
D	ARG9
D	LYS11
D	TYR13
D	ASP56
D	GLN103
D	TYR281
D	1PE314
P	LYS11
P	TYR13
P	ASP56
P	1PE313

---

site_id	AD3
Number of Residues	9
Details	binding site for residue 1PE P 313

Chain	Residue
D	LYS105
D	1PE314
P	ASP56
P	HIS57
P	PRO58
P	LYS61
P	LYS105
P	ASP110
P	1PE312

---

site_id	AD4
Number of Residues	7
Details	binding site for residue FE P 314

Chain	Residue
P	ASP122
P	HIS123
P	ASP220
P	HIS266
P	CO301
P	HL4304
P	HOH401

---

site_id	AD5
Number of Residues	2
Details	binding site for residue ACT P 315

Chain	Residue
P	ARG19
P	LYS272

---

site_id	AD6
Number of Residues	5
Details	binding site for residue PGE P 316

Chain	Residue
P	ASN182
P	LYS190
P	HIS206
P	ILE254
P	SO4302

---

site_id	AD7
Number of Residues	2
Details	binding site for residue PGE P 317

Chain	Residue
P	ARG174
P	ILE183

---

site_id	AD8
Number of Residues	7
Details	binding site for residue CO D 301

Chain	Residue
D	HIS118
D	HIS120
D	HIS198
D	ASP220
D	HL4305
D	FE316
D	HOH402

---

site_id	AD9
Number of Residues	5
Details	binding site for residue SO4 D 302

Chain	Residue
D	ASN182
D	ARG250
D	ARG253
D	ILE254
D	PGE319

---

site_id	AE1
Number of Residues	4
Details	binding site for residue SO4 D 303

Chain	Residue
D	ARG178
D	HIS179
P	ARG178
P	HIS179

---

site_id	AE2
Number of Residues	6
Details	binding site for residue SO4 D 304

Chain	Residue
D	GLU109
D	ASP110
D	ILE111
D	ARG112
D	ASN132
D	HOH412

---

site_id	AE3
Number of Residues	13
Details	binding site for residue HL4 D 305

Chain	Residue
D	MET22
D	PHE48
D	HIS120
D	ASP122
D	ALA157
D	HIS198
D	ASP220
D	TYR223
D	HIS266
D	CO301
D	EDO311
D	FE316
D	HOH402

---

site_id	AE4
Number of Residues	3
Details	binding site for residue EDO D 306

Chain	Residue
D	GLN261
D	VAL262
D	PHE264

---

site_id	AE5
Number of Residues	1
Details	binding site for residue EDO D 307

Chain	Residue
D	THR134

---

site_id	AE6
Number of Residues	6
Details	binding site for residue EDO D 308

Chain	Residue
D	GLU139
D	ASN143
D	HOH410
P	ASP140
P	GLN147
P	HOH431

---

site_id	AE7
Number of Residues	2
Details	binding site for residue EDO D 309

Chain	Residue
D	PRO210
D	GLU211

---

site_id	AE8
Number of Residues	3
Details	binding site for residue EDO D 310

Chain	Residue
D	ALA255
D	GLN256
D	HOH436

---

site_id	AE9
Number of Residues	1
Details	binding site for residue EDO D 311

Chain	Residue
D	HL4305

---

site_id	AF1
Number of Residues	5
Details	binding site for residue EDO D 312

Chain	Residue
D	PRO70
D	SER72
D	MET73
D	TRP89
D	TYR96

---

site_id	AF2
Number of Residues	4
Details	binding site for residue EDO D 313

Chain	Residue
D	HIS120
D	TYR158
D	ALA199
D	TRP200

---

site_id	AF3
Number of Residues	9
Details	binding site for residue 1PE D 314

Chain	Residue
D	LYS105
D	HOH401
P	ARG9
P	TYR13
P	ASP56
P	LEU104
P	LYS105
P	1PE312
P	1PE313

---

site_id	AF4
Number of Residues	7
Details	binding site for residue 1PE D 315

Chain	Residue
D	ARG174
D	LEU184
D	LEU185
D	GLU249
D	ARG253
D	GLN256
D	HOH484

---

site_id	AF5
Number of Residues	7
Details	binding site for residue FE D 316

Chain	Residue
D	ASP122
D	HIS123
D	ASP220
D	HIS266
D	CO301
D	HL4305
D	HOH402

---

site_id	AF6
Number of Residues	5
Details	binding site for residue ACT D 317

Chain	Residue
D	TRP173
D	ARG174
D	THR175
D	LYS177
P	ARG151

---

site_id	AF7
Number of Residues	2
Details	binding site for residue ACT D 318

Chain	Residue
D	ARG19
D	LYS272

---

site_id	AF8
Number of Residues	6
Details	binding site for residue PGE D 319

Chain	Residue
D	GLY188
D	LYS190
D	LEU192
D	HIS206
D	SO4302
D	HOH469

---

site_id	AF9
Number of Residues	7
Details	binding site for residue PGE D 320

Chain	Residue
D	GLY236
D	ILE237
D	ILE238
P	PRO235
P	GLY236
P	ILE237
P	ILE238

---