Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6N9I

Structure of the Quorum Quenching lactonase from Parageobacillus caldoxylosilyticus - free

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
B	0016787	molecular_function	hydrolase activity
B	0046872	molecular_function	metal ion binding
C	0016787	molecular_function	hydrolase activity
C	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue CO A 301

Chain	Residue
A	HIS118
A	HIS120
A	HIS198
A	ASP220
A	FE313
A	HOH422
A	HOH498

site_id	AC2
Number of Residues	3
Details	binding site for residue SO4 A 302

Chain	Residue
A	ARG253
A	ASN182
A	ARG250

site_id	AC3
Number of Residues	8
Details	binding site for residue SO4 A 303

Chain	Residue
A	ARG253
A	HOH414
A	HOH424
A	HOH426
C	GLU180
C	ASP181
C	HOH505
C	HOH604

site_id	AC4
Number of Residues	6
Details	binding site for residue SO4 A 304

Chain	Residue
A	TRP173
A	ARG174
A	THR175
A	LYS177
A	HOH460
B	ARG151

site_id	AC5
Number of Residues	2
Details	binding site for residue ACT A 305

Chain	Residue
A	ARG9
A	ASP56

site_id	AC6
Number of Residues	3
Details	binding site for residue ACT A 306

Chain	Residue
A	ASN32
A	ASN38
A	GLN42

site_id	AC7
Number of Residues	5
Details	binding site for residue EDO A 307

Chain	Residue
A	SER196
A	TYR239
A	ASP240
A	HOH490
C	LEU242

site_id	AC8
Number of Residues	5
Details	binding site for residue EDO A 308

Chain	Residue
A	ASN71
A	ARG78
A	HOH492
B	GLU109
B	ASN132

site_id	AC9
Number of Residues	3
Details	binding site for residue EDO A 309

Chain	Residue
A	ARG174
A	ILE183
A	HOH404

site_id	AD1
Number of Residues	2
Details	binding site for residue EDO A 310

Chain	Residue
A	HOH418
A	HOH488

site_id	AD2
Number of Residues	4
Details	binding site for residue EDO A 311

Chain	Residue
A	ASN152
A	GLN153
A	LYS154
A	GLU155

site_id	AD3
Number of Residues	7
Details	binding site for residue EDO A 312

Chain	Residue
A	GLU94
A	ASN99
A	ARG100
A	GLN103
A	THR278
A	HOH402
A	HOH405

site_id	AD4
Number of Residues	7
Details	binding site for residue FE A 313

Chain	Residue
A	ASP122
A	HIS123
A	ASP220
A	HIS266
A	CO301
A	HOH422
A	HOH525

site_id	AD5
Number of Residues	11
Details	binding site for residue PGE A 314

Chain	Residue
A	HIS120
A	TYR158
A	HIS198
A	ALA199
A	TRP200
A	ILE237
A	TYR239
A	PGE315
A	HOH418
A	HOH488
A	HOH505

site_id	AD6
Number of Residues	10
Details	binding site for residue PGE A 315

Chain	Residue
A	GLY144
A	GLN147
A	CYS148
A	GLN153
A	TRP200
A	PGE314
A	HOH453
A	HOH505
B	HOH539
B	HOH630

site_id	AD7
Number of Residues	7
Details	binding site for residue CO B 301

Chain	Residue
B	HIS118
B	HIS120
B	HIS198
B	ASP220
B	FE318
B	HOH429
B	HOH536

site_id	AD8
Number of Residues	4
Details	binding site for residue SO4 B 302

Chain	Residue
B	ARG250
B	ARG253
B	ILE254
B	GOL309

site_id	AD9
Number of Residues	6
Details	binding site for residue SO4 B 303

Chain	Residue
B	HOH516
A	ARG151
B	ARG174
B	THR175
B	LYS177
B	HOH411

site_id	AE1
Number of Residues	7
Details	binding site for residue SO4 B 304

Chain	Residue
B	GLU180
B	ASP181
B	HOH456
B	HOH497
C	ARG253
C	HOH470
C	HOH598

site_id	AE2
Number of Residues	7
Details	binding site for residue SO4 B 305

Chain	Residue
A	GLU180
A	ASP181
B	ARG253
B	HOH428
B	HOH430
B	HOH443
B	HOH481

site_id	AE3
Number of Residues	3
Details	binding site for residue SO4 B 306

Chain	Residue
B	ASN71
B	ARG78
B	HOH405

site_id	AE4
Number of Residues	3
Details	binding site for residue SO4 B 307

Chain	Residue
C	ARG250
C	ARG253
C	EDO306

site_id	AE5
Number of Residues	5
Details	binding site for residue SO4 B 308

Chain	Residue
B	ASN32
B	ASN38
B	ALA41
B	GLN42
B	HOH537

site_id	AE6
Number of Residues	4
Details	binding site for residue GOL B 309

Chain	Residue
B	ASN182
B	LYS190
B	HIS206
B	SO4302

site_id	AE7
Number of Residues	5
Details	binding site for residue ACT B 310

Chain	Residue
B	ARG178
B	SER196
B	TYR239
B	HOH496
B	HOH612

site_id	AE8
Number of Residues	5
Details	binding site for residue ACT B 311

Chain	Residue
B	GLN261
B	VAL262
B	PHE264
B	GLN270
B	HOH492

site_id	AE9
Number of Residues	2
Details	binding site for residue EDO B 312

Chain	Residue
B	ARG174
C	HOH615

site_id	AF1
Number of Residues	6
Details	binding site for residue EDO B 313

Chain	Residue
B	TYR158
B	ALA199
B	TRP200
B	HOH475
B	HOH544
B	HOH583

site_id	AF2
Number of Residues	4
Details	binding site for residue EDO B 314

Chain	Residue
A	ARG178
A	HIS179
B	ARG178
B	HIS179

site_id	AF3
Number of Residues	4
Details	binding site for residue EDO B 316

Chain	Residue
B	GLN261
B	LYS273
B	TYR282
B	HOH415

site_id	AF4
Number of Residues	4
Details	binding site for residue EDO B 317

Chain	Residue
B	ASN152
B	GLN153
B	LYS154
B	GLU155

site_id	AF5
Number of Residues	7
Details	binding site for residue FE B 318

Chain	Residue
B	ASP122
B	HIS123
B	ASP220
B	HIS266
B	CO301
B	HOH429
B	HOH522

site_id	AF6
Number of Residues	7
Details	binding site for residue CO C 301

Chain	Residue
C	HIS118
C	HIS120
C	HIS198
C	ASP220
C	FE313
C	HOH420
C	HOH535

site_id	AF7
Number of Residues	6
Details	binding site for residue SO4 C 302

Chain	Residue
C	ARG151
C	ARG174
C	THR175
C	LYS177
C	HOH411
C	HOH579

site_id	AF8
Number of Residues	9
Details	binding site for residue GOL C 303

Chain	Residue
C	TYR158
C	ALA199
C	TRP200
C	TYR239
C	HOH415
C	HOH435
C	HOH443
C	HOH512
C	HOH540

site_id	AF9
Number of Residues	2
Details	binding site for residue ACT C 304

Chain	Residue
C	ASN71
C	ARG78

site_id	AG1
Number of Residues	5
Details	binding site for residue ACT C 305

Chain	Residue
C	GLN261
C	VAL262
C	PHE264
C	GLN270
C	HOH445

site_id	AG2
Number of Residues	2
Details	binding site for residue EDO C 306

Chain	Residue
B	SO4307
C	ASN182

site_id	AG3
Number of Residues	2
Details	binding site for residue EDO C 307

Chain	Residue
C	TYR113
C	ARG174

site_id	AG4
Number of Residues	6
Details	binding site for residue EDO C 308

Chain	Residue
C	LYS24
C	HIS31
C	ASN32
C	ASN38
C	GLU44
C	HOH410

site_id	AG5
Number of Residues	6
Details	binding site for residue EDO C 309

Chain	Residue
C	GLY144
C	CYS148
C	GLN153
C	TRP200
C	HOH486
C	HOH613

site_id	AG6
Number of Residues	2
Details	binding site for residue EDO C 310

Chain	Residue
C	HOH443
C	HOH557

site_id	AG7
Number of Residues	2
Details	binding site for residue EDO C 311

Chain	Residue
C	GLN261
C	TYR282

site_id	AG8
Number of Residues	4
Details	binding site for residue EDO C 312

Chain	Residue
C	ARG178
C	SER196
C	TYR239
C	HOH513

site_id	AG9
Number of Residues	7
Details	binding site for residue FE C 313

Chain	Residue
C	ASP122
C	HIS123
C	ASP220
C	HIS266
C	CO301
C	HOH420
C	HOH564

site_id	AH1
Number of Residues	20
Details	binding site for residues PGE B 319 and PGE C 314

Chain	Residue
A	ARG178
A	HIS179
B	LYS11
B	TYR13
B	TYR13
B	LEU104
B	LEU104
B	ARG178
B	HIS179
B	TYR281
B	TYR281
C	LYS11
C	LYS11
C	TYR13
C	TYR13
C	LEU104
C	LEU104
C	TYR281
C	TYR281
C	HOH404

site_id	AH2
Number of Residues	20
Details	binding site for residues PGE B 319 and PGE C 314

Chain	Residue
A	ARG178
A	HIS179
B	LYS11
B	TYR13
B	TYR13
B	LEU104
B	LEU104
B	ARG178
B	HIS179
B	TYR281
B	TYR281
C	LYS11
C	LYS11
C	TYR13
C	TYR13
C	LEU104
C	LEU104
C	TYR281
C	TYR281
C	HOH404

site_id	AH3
Number of Residues	20
Details	binding site for residues PGE B 319 and PGE C 314

Chain	Residue
A	ARG178
A	HIS179
B	LYS11
B	TYR13
B	TYR13
B	LEU104
B	LEU104
B	ARG178
B	HIS179
B	TYR281
B	TYR281
C	LYS11
C	LYS11
C	TYR13
C	TYR13
C	LEU104
C	LEU104
C	TYR281
C	TYR281
C	HOH404

site_id	AH4
Number of Residues	20
Details	binding site for residues PGE B 319 and PGE C 314

Chain	Residue
A	ARG178
A	HIS179
B	LYS11
B	TYR13
B	TYR13
B	LEU104
B	LEU104
B	ARG178
B	HIS179
B	TYR281
B	TYR281
C	LYS11
C	LYS11
C	TYR13
C	TYR13
C	LEU104
C	LEU104
C	TYR281
C	TYR281
C	HOH404

site_id	AH5
Number of Residues	20
Details	binding site for residues PGE B 319 and PGE C 314

Chain	Residue
A	ARG178
A	HIS179
B	LYS11
B	TYR13
B	TYR13
B	LEU104
B	LEU104
B	ARG178
B	HIS179
B	TYR281
B	TYR281
C	LYS11
C	LYS11
C	TYR13
C	TYR13
C	LEU104
C	LEU104
C	TYR281
C	TYR281
C	HOH404

site_id	AH6
Number of Residues	20
Details	binding site for residues PGE B 319 and PGE C 314

Chain	Residue
A	ARG178
A	HIS179
B	LYS11
B	TYR13
B	TYR13
B	LEU104
B	LEU104
B	ARG178
B	HIS179
B	TYR281
B	TYR281
C	LYS11
C	LYS11
C	TYR13
C	TYR13
C	LEU104
C	LEU104
C	TYR281
C	TYR281
C	HOH404

site_id	AH7
Number of Residues	20
Details	binding site for residues PGE B 319 and PGE C 314

Chain	Residue
A	ARG178
A	HIS179
B	LYS11
B	TYR13
B	TYR13
B	LEU104
B	LEU104
B	ARG178
B	HIS179
B	TYR281
B	TYR281
C	LYS11
C	LYS11
C	TYR13
C	TYR13
C	LEU104
C	LEU104
C	TYR281
C	TYR281
C	HOH404

site_id	AH8
Number of Residues	20
Details	binding site for residues PGE B 319 and PGE C 314

Chain	Residue
A	ARG178
A	HIS179
B	LYS11
B	TYR13
B	TYR13
B	LEU104
B	LEU104
B	ARG178
B	HIS179
B	TYR281
B	TYR281
C	LYS11
C	LYS11
C	TYR13
C	TYR13
C	LEU104
C	LEU104
C	TYR281
C	TYR281
C	HOH404

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)