6N6Q
Crystal structure of a Cytochrome P450 (CYP102L1)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0020037 | molecular_function | heme binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| B | 0020037 | molecular_function | heme binding |
| C | 0004497 | molecular_function | monooxygenase activity |
| C | 0005506 | molecular_function | iron ion binding |
| C | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| C | 0020037 | molecular_function | heme binding |
| D | 0004497 | molecular_function | monooxygenase activity |
| D | 0005506 | molecular_function | iron ion binding |
| D | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| D | 0020037 | molecular_function | heme binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | binding site for residue HEM A 501 |
| Chain | Residue |
| A | LYS90 |
| A | SER294 |
| A | VAL355 |
| A | ALA356 |
| A | TYR359 |
| A | PRO422 |
| A | GLY424 |
| A | ARG428 |
| A | ALA429 |
| A | CYS430 |
| A | ILE431 |
| A | MET107 |
| A | ALA436 |
| A | HOH610 |
| A | HOH612 |
| A | HOH617 |
| A | HOH618 |
| A | HOH633 |
| A | PHE108 |
| A | TRP117 |
| A | PHE128 |
| A | PHE286 |
| A | ALA289 |
| A | GLY290 |
| A | THR293 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CAC A 502 |
| Chain | Residue |
| A | TYR111 |
| A | ASN112 |
| A | SER113 |
| A | GLN362 |
| A | HOH608 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | binding site for residue HEM B 501 |
| Chain | Residue |
| B | LYS90 |
| B | LEU96 |
| B | MET107 |
| B | PHE108 |
| B | TRP117 |
| B | ILE175 |
| B | ALA289 |
| B | GLY290 |
| B | THR293 |
| B | SER294 |
| B | TYR359 |
| B | PRO422 |
| B | PHE423 |
| B | GLY424 |
| B | ARG428 |
| B | ALA429 |
| B | CYS430 |
| B | ILE431 |
| B | GLY432 |
| B | ALA436 |
| B | HOH604 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue CAC B 502 |
| Chain | Residue |
| B | GLU89 |
| B | TYR111 |
| B | ASN112 |
| B | SER113 |
| B | GLN362 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue CAC B 503 |
| Chain | Residue |
| B | GLY30 |
| B | GLY30 |
| B | ARG31 |
| B | ARG31 |
| B | LEU32 |
| site_id | AC6 |
| Number of Residues | 22 |
| Details | binding site for residue HEM C 501 |
| Chain | Residue |
| C | LYS90 |
| C | MET107 |
| C | PHE108 |
| C | TRP117 |
| C | ALA289 |
| C | GLY290 |
| C | THR293 |
| C | SER294 |
| C | VAL355 |
| C | TYR359 |
| C | PRO422 |
| C | PHE423 |
| C | GLY424 |
| C | ARG428 |
| C | ALA429 |
| C | CYS430 |
| C | ALA436 |
| C | HOH603 |
| C | HOH604 |
| C | HOH607 |
| C | HOH611 |
| C | HOH615 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue CAC C 502 |
| Chain | Residue |
| C | GLU89 |
| C | TYR111 |
| C | ASN112 |
| C | SER113 |
| C | GLN362 |
| C | HOH606 |
| site_id | AC8 |
| Number of Residues | 25 |
| Details | binding site for residue HEM D 501 |
| Chain | Residue |
| D | ALA356 |
| D | TYR359 |
| D | PRO422 |
| D | PHE423 |
| D | GLY424 |
| D | ARG428 |
| D | ALA429 |
| D | CYS430 |
| D | ILE431 |
| D | ALA436 |
| D | GLU439 |
| D | HOH602 |
| D | HOH605 |
| D | HOH607 |
| D | HOH611 |
| D | LYS90 |
| D | MET107 |
| D | PHE108 |
| D | TRP117 |
| D | PHE128 |
| D | ILE175 |
| D | ALA289 |
| D | GLY290 |
| D | THR293 |
| D | SER294 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue CAC D 502 |
| Chain | Residue |
| D | TYR111 |
| D | ASN112 |
| D | SER113 |
| D | GLN362 |
Functional Information from PROSITE/UniProt
| site_id | PS00086 |
| Number of Residues | 10 |
| Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGvGERACIG |
| Chain | Residue | Details |
| A | PHE423-GLY432 |
