6N6P
Crystal structure of [FeFe]-hydrogenase in the presence of 7 mM Sodium dithionite
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0008901 | molecular_function | ferredoxin hydrogenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue 402 A 601 |
| Chain | Residue |
| A | ALA230 |
| A | PRO354 |
| A | CYS355 |
| A | LYS358 |
| A | PHE417 |
| A | MET497 |
| A | CYS503 |
| A | SF4602 |
| A | PRO231 |
| A | SER232 |
| A | ILE268 |
| A | ALA272 |
| A | CYS299 |
| A | PRO324 |
| A | GLN325 |
| A | MET353 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue SF4 A 602 |
| Chain | Residue |
| A | CYS300 |
| A | PRO301 |
| A | PRO354 |
| A | CYS355 |
| A | SER357 |
| A | ALA498 |
| A | CYS499 |
| A | CYS503 |
| A | GLY506 |
| A | 402601 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue SF4 A 603 |
| Chain | Residue |
| A | LEU140 |
| A | CYS157 |
| A | MET166 |
| A | CYS190 |
| A | LEU191 |
| A | LEU192 |
| A | CYS193 |
| A | GLY194 |
| A | CYS196 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | binding site for residue SF4 A 604 |
| Chain | Residue |
| A | CYS147 |
| A | LEU148 |
| A | LEU149 |
| A | CYS150 |
| A | GLY151 |
| A | CYS153 |
| A | ILE177 |
| A | CYS200 |
| A | VAL202 |
| A | ALA204 |
| A | LEU205 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | binding site for residue SF4 A 605 |
| Chain | Residue |
| A | HIS94 |
| A | GLU95 |
| A | PHE96 |
| A | LYS97 |
| A | CYS98 |
| A | CYS101 |
| A | ARG104 |
| A | CYS107 |
| A | LYS146 |
| A | VAL202 |
| A | ALA203 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue FES A 606 |
| Chain | Residue |
| A | ALA32 |
| A | LEU33 |
| A | CYS34 |
| A | PHE35 |
| A | LYS45 |
| A | CYS46 |
| A | GLU47 |
| A | CYS49 |
| A | CYS62 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 607 |
| Chain | Residue |
| A | LYS223 |
| A | LYS333 |
| A | LYS345 |
| A | VAL347 |
| A | PHE348 |
| A | LEU372 |
| A | ARG373 |
| A | ASP376 |
| A | HOH805 |
| A | HOH1051 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 608 |
| Chain | Residue |
| A | ARG104 |
| A | GLU105 |
| A | ASN106 |
| A | CYS107 |
| A | LEU110 |
| A | LYS111 |
| A | HOH817 |
| A | HOH983 |
Functional Information from PROSITE/UniProt
| site_id | PS00198 |
| Number of Residues | 12 |
| Details | 4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. ClLCGrCVnACG |
| Chain | Residue | Details |
| A | CYS147-GLY158 | |
| A | CYS190-PRO201 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 77 |
| Details | Domain: {"description":"2Fe-2S ferredoxin-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00465","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 39 |
| Details | Domain: {"description":"4Fe-4S His(Cys)3-ligated-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01184","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 29 |
| Details | Domain: {"description":"4Fe-4S ferredoxin-type 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 29 |
| Details | Domain: {"description":"4Fe-4S ferredoxin-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00711","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 15 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10529166","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9836629","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01184","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"10529166","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01184","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"10529166","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9836629","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10529166","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
