Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6MX2

Crystal Structure of ClpP1 from Clostridium difficile 630.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004176	molecular_function	ATP-dependent peptidase activity
A	0004252	molecular_function	serine-type endopeptidase activity
A	0005737	cellular_component	cytoplasm
A	0006508	biological_process	proteolysis
A	0008236	molecular_function	serine-type peptidase activity
B	0004176	molecular_function	ATP-dependent peptidase activity
B	0004252	molecular_function	serine-type endopeptidase activity
B	0005737	cellular_component	cytoplasm
B	0006508	biological_process	proteolysis
B	0008236	molecular_function	serine-type peptidase activity
C	0004176	molecular_function	ATP-dependent peptidase activity
C	0004252	molecular_function	serine-type endopeptidase activity
C	0005737	cellular_component	cytoplasm
C	0006508	biological_process	proteolysis
C	0008236	molecular_function	serine-type peptidase activity
D	0004176	molecular_function	ATP-dependent peptidase activity
D	0004252	molecular_function	serine-type endopeptidase activity
D	0005737	cellular_component	cytoplasm
D	0006508	biological_process	proteolysis
D	0008236	molecular_function	serine-type peptidase activity
E	0004176	molecular_function	ATP-dependent peptidase activity
E	0004252	molecular_function	serine-type endopeptidase activity
E	0005737	cellular_component	cytoplasm
E	0006508	biological_process	proteolysis
E	0008236	molecular_function	serine-type peptidase activity
F	0004176	molecular_function	ATP-dependent peptidase activity
F	0004252	molecular_function	serine-type endopeptidase activity
F	0005737	cellular_component	cytoplasm
F	0006508	biological_process	proteolysis
F	0008236	molecular_function	serine-type peptidase activity
G	0004176	molecular_function	ATP-dependent peptidase activity
G	0004252	molecular_function	serine-type endopeptidase activity
G	0005737	cellular_component	cytoplasm
G	0006508	biological_process	proteolysis
G	0008236	molecular_function	serine-type peptidase activity
H	0004176	molecular_function	ATP-dependent peptidase activity
H	0004252	molecular_function	serine-type endopeptidase activity
H	0005737	cellular_component	cytoplasm
H	0006508	biological_process	proteolysis
H	0008236	molecular_function	serine-type peptidase activity
I	0004176	molecular_function	ATP-dependent peptidase activity
I	0004252	molecular_function	serine-type endopeptidase activity
I	0005737	cellular_component	cytoplasm
I	0006508	biological_process	proteolysis
I	0008236	molecular_function	serine-type peptidase activity
J	0004176	molecular_function	ATP-dependent peptidase activity
J	0004252	molecular_function	serine-type endopeptidase activity
J	0005737	cellular_component	cytoplasm
J	0006508	biological_process	proteolysis
J	0008236	molecular_function	serine-type peptidase activity
K	0004176	molecular_function	ATP-dependent peptidase activity
K	0004252	molecular_function	serine-type endopeptidase activity
K	0005737	cellular_component	cytoplasm
K	0006508	biological_process	proteolysis
K	0008236	molecular_function	serine-type peptidase activity
L	0004176	molecular_function	ATP-dependent peptidase activity
L	0004252	molecular_function	serine-type endopeptidase activity
L	0005737	cellular_component	cytoplasm
L	0006508	biological_process	proteolysis
L	0008236	molecular_function	serine-type peptidase activity
M	0004176	molecular_function	ATP-dependent peptidase activity
M	0004252	molecular_function	serine-type endopeptidase activity
M	0005737	cellular_component	cytoplasm
M	0006508	biological_process	proteolysis
M	0008236	molecular_function	serine-type peptidase activity
N	0004176	molecular_function	ATP-dependent peptidase activity
N	0004252	molecular_function	serine-type endopeptidase activity
N	0005737	cellular_component	cytoplasm
N	0006508	biological_process	proteolysis
N	0008236	molecular_function	serine-type peptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue NA A 201

Chain	Residue
A	MET80
A	ILE83
A	PRO85
A	HOH322

site_id	AC2
Number of Residues	4
Details	binding site for residue NA B 201

Chain	Residue
B	MET80
B	ILE83
B	PRO85
B	HOH337

site_id	AC3
Number of Residues	4
Details	binding site for residue NA C 201

Chain	Residue
C	ILE83
C	PRO85
C	HOH339
C	MET80

site_id	AC4
Number of Residues	3
Details	binding site for residue NA D 201

Chain	Residue
D	MET80
D	ILE83
D	PRO85

site_id	AC5
Number of Residues	4
Details	binding site for residue NA E 201

Chain	Residue
E	MET80
E	ILE83
E	PRO85
E	HOH351

site_id	AC6
Number of Residues	6
Details	binding site for residue NA F 201

Chain	Residue
F	MET80
F	ILE83
F	PRO85
F	HOH306
F	HOH318
F	HOH320

site_id	AC7
Number of Residues	4
Details	binding site for residue NA G 201

Chain	Residue
G	MET80
G	ILE83
G	PRO85
G	HOH333

site_id	AC8
Number of Residues	4
Details	binding site for residue NA G 202

Chain	Residue
G	GLY67
G	GLY68
G	SER97
G	MET98

site_id	AC9
Number of Residues	5
Details	binding site for residue NA H 201

Chain	Residue
H	MET80
H	ILE83
H	PRO85
H	HOH333
I	HOH314

site_id	AD1
Number of Residues	4
Details	binding site for residue NA I 201

Chain	Residue
I	MET80
I	ILE83
I	PRO85
I	HOH342

site_id	AD2
Number of Residues	4
Details	binding site for residue NA I 202

Chain	Residue
I	GLY68
I	SER97
I	MET98
I	HOH352

site_id	AD3
Number of Residues	5
Details	binding site for residue NA J 201

Chain	Residue
J	MET80
J	ILE83
J	PRO85
J	HOH332
K	HOH349

site_id	AD4
Number of Residues	4
Details	binding site for residue NA K 201

Chain	Residue
K	MET80
K	ILE83
K	PRO85
K	HOH345

site_id	AD5
Number of Residues	4
Details	binding site for residue NA L 201

Chain	Residue
L	MET80
L	ILE83
L	PRO85
L	HOH329

site_id	AD6
Number of Residues	4
Details	binding site for residue NA L 202

Chain	Residue
L	LYS146
L	GLU147
L	ASN150
L	LYS165

site_id	AD7
Number of Residues	4
Details	binding site for residue GOL M 201

Chain	Residue
M	SER97
M	MET98
M	HIS122
M	LEU149

site_id	AD8
Number of Residues	4
Details	binding site for residue NA M 202

Chain	Residue
M	MET80
M	ILE83
M	PRO85
M	HOH333

site_id	AD9
Number of Residues	5
Details	binding site for residue GOL N 201

Chain	Residue
N	SER97
N	MET98
N	ILE121
N	HIS122
N	LEU149

site_id	AE1
Number of Residues	5
Details	binding site for residue NA N 202

Chain	Residue
N	MET80
N	ILE83
N	LYS84
N	PRO85
N	HOH328

Functional Information from PROSITE/UniProt

site_id	PS00381
Number of Residues	12
Details	CLP_PROTEASE_SER Endopeptidase Clp serine active site. TicIGmAASMGA

Chain	Residue	Details
A	THR89-ALA100

site_id	PS00382
Number of Residues	14
Details	CLP_PROTEASE_HIS Endopeptidase Clp histidine active site. RlalPnseIMIHQP

Chain	Residue	Details
A	ARG111-PRO124

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)