6MWW

LasR LBD:BB0126 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0001216	molecular_function	DNA-binding transcription activator activity
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
A	0009372	biological_process	quorum sensing
A	0010468	biological_process	regulation of gene expression
A	0032993	cellular_component	protein-DNA complex
A	0043565	molecular_function	sequence-specific DNA binding
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0051544	biological_process	positive regulation of elastin biosynthetic process
A	0060310	biological_process	regulation of elastin catabolic process
B	0000976	molecular_function	transcription cis-regulatory region binding
B	0001216	molecular_function	DNA-binding transcription activator activity
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006355	biological_process	regulation of DNA-templated transcription
B	0009372	biological_process	quorum sensing
B	0010468	biological_process	regulation of gene expression
B	0032993	cellular_component	protein-DNA complex
B	0043565	molecular_function	sequence-specific DNA binding
B	0045893	biological_process	positive regulation of DNA-templated transcription
B	0051544	biological_process	positive regulation of elastin biosynthetic process
B	0060310	biological_process	regulation of elastin catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	binding site for residue K5J A 301

Chain	Residue
A	GLY38
A	VAL76
A	TRP88
A	PHE101
A	LEU110
A	LEU125
A	GLY126
A	ALA127
A	SER129
A	LEU39
A	LEU40
A	TYR47
A	ALA50
A	TYR56
A	TRP60
A	ASP73
A	THR75

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site_id	AC2
Number of Residues	16
Details	binding site for residue K5J B 301

Chain	Residue
B	GLY38
B	LEU39
B	LEU40
B	TYR47
B	TYR56
B	TRP60
B	ASP73
B	THR75
B	VAL76
B	TRP88
B	PHE101
B	LEU110
B	LEU125
B	GLY126
B	ALA127
B	SER129

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Functional Information from PROSITE/UniProt

site_id	PS00622
Number of Residues	28
Details	HTH_LUXR_1 LuxR-type HTH domain signature. GktSweISviCnCseaNVnfHmgNIrrK

Chain	Residue	Details
A	GLY191-LYS218

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	38
Details	DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00411

Chain	Residue	Details
A	SER194-GLY213
B	SER194-GLY213

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