6MRT

12-meric ClyA pore complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0016020	cellular_component	membrane
A	0020002	cellular_component	host cell plasma membrane
A	0031640	biological_process	killing of cells of another organism
A	0042597	cellular_component	periplasmic space
A	0042802	molecular_function	identical protein binding
A	0044179	biological_process	hemolysis in another organism
A	0044532	biological_process	modulation of apoptotic process in another organism
A	0090729	molecular_function	toxin activity
B	0005576	cellular_component	extracellular region
B	0016020	cellular_component	membrane
B	0020002	cellular_component	host cell plasma membrane
B	0031640	biological_process	killing of cells of another organism
B	0042597	cellular_component	periplasmic space
B	0042802	molecular_function	identical protein binding
B	0044179	biological_process	hemolysis in another organism
B	0044532	biological_process	modulation of apoptotic process in another organism
B	0090729	molecular_function	toxin activity
C	0005576	cellular_component	extracellular region
C	0016020	cellular_component	membrane
C	0020002	cellular_component	host cell plasma membrane
C	0031640	biological_process	killing of cells of another organism
C	0042597	cellular_component	periplasmic space
C	0042802	molecular_function	identical protein binding
C	0044179	biological_process	hemolysis in another organism
C	0044532	biological_process	modulation of apoptotic process in another organism
C	0090729	molecular_function	toxin activity
D	0005576	cellular_component	extracellular region
D	0016020	cellular_component	membrane
D	0020002	cellular_component	host cell plasma membrane
D	0031640	biological_process	killing of cells of another organism
D	0042597	cellular_component	periplasmic space
D	0042802	molecular_function	identical protein binding
D	0044179	biological_process	hemolysis in another organism
D	0044532	biological_process	modulation of apoptotic process in another organism
D	0090729	molecular_function	toxin activity
E	0005576	cellular_component	extracellular region
E	0016020	cellular_component	membrane
E	0020002	cellular_component	host cell plasma membrane
E	0031640	biological_process	killing of cells of another organism
E	0042597	cellular_component	periplasmic space
E	0042802	molecular_function	identical protein binding
E	0044179	biological_process	hemolysis in another organism
E	0044532	biological_process	modulation of apoptotic process in another organism
E	0090729	molecular_function	toxin activity
F	0005576	cellular_component	extracellular region
F	0016020	cellular_component	membrane
F	0020002	cellular_component	host cell plasma membrane
F	0031640	biological_process	killing of cells of another organism
F	0042597	cellular_component	periplasmic space
F	0042802	molecular_function	identical protein binding
F	0044179	biological_process	hemolysis in another organism
F	0044532	biological_process	modulation of apoptotic process in another organism
F	0090729	molecular_function	toxin activity
G	0005576	cellular_component	extracellular region
G	0016020	cellular_component	membrane
G	0020002	cellular_component	host cell plasma membrane
G	0031640	biological_process	killing of cells of another organism
G	0042597	cellular_component	periplasmic space
G	0042802	molecular_function	identical protein binding
G	0044179	biological_process	hemolysis in another organism
G	0044532	biological_process	modulation of apoptotic process in another organism
G	0090729	molecular_function	toxin activity
H	0005576	cellular_component	extracellular region
H	0016020	cellular_component	membrane
H	0020002	cellular_component	host cell plasma membrane
H	0031640	biological_process	killing of cells of another organism
H	0042597	cellular_component	periplasmic space
H	0042802	molecular_function	identical protein binding
H	0044179	biological_process	hemolysis in another organism
H	0044532	biological_process	modulation of apoptotic process in another organism
H	0090729	molecular_function	toxin activity
I	0005576	cellular_component	extracellular region
I	0016020	cellular_component	membrane
I	0020002	cellular_component	host cell plasma membrane
I	0031640	biological_process	killing of cells of another organism
I	0042597	cellular_component	periplasmic space
I	0042802	molecular_function	identical protein binding
I	0044179	biological_process	hemolysis in another organism
I	0044532	biological_process	modulation of apoptotic process in another organism
I	0090729	molecular_function	toxin activity
J	0005576	cellular_component	extracellular region
J	0016020	cellular_component	membrane
J	0020002	cellular_component	host cell plasma membrane
J	0031640	biological_process	killing of cells of another organism
J	0042597	cellular_component	periplasmic space
J	0042802	molecular_function	identical protein binding
J	0044179	biological_process	hemolysis in another organism
J	0044532	biological_process	modulation of apoptotic process in another organism
J	0090729	molecular_function	toxin activity
K	0005576	cellular_component	extracellular region
K	0016020	cellular_component	membrane
K	0020002	cellular_component	host cell plasma membrane
K	0031640	biological_process	killing of cells of another organism
K	0042597	cellular_component	periplasmic space
K	0042802	molecular_function	identical protein binding
K	0044179	biological_process	hemolysis in another organism
K	0044532	biological_process	modulation of apoptotic process in another organism
K	0090729	molecular_function	toxin activity
L	0005576	cellular_component	extracellular region
L	0016020	cellular_component	membrane
L	0020002	cellular_component	host cell plasma membrane
L	0031640	biological_process	killing of cells of another organism
L	0042597	cellular_component	periplasmic space
L	0042802	molecular_function	identical protein binding
L	0044179	biological_process	hemolysis in another organism
L	0044532	biological_process	modulation of apoptotic process in another organism
L	0090729	molecular_function	toxin activity

Functional Information from PROSITE/UniProt

site_id	PS00136
Number of Residues	12
Details	SUBTILASE_ASP Serine proteases, subtilase family, aspartic acid active site. IKVLDDGItklN

Chain	Residue	Details
A	ILE117-ASN128

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	240
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
A	ALA183-VAL203
J	ALA183-VAL203
K	ALA183-VAL203
L	ALA183-VAL203
B	ALA183-VAL203
C	ALA183-VAL203
D	ALA183-VAL203
E	ALA183-VAL203
F	ALA183-VAL203
G	ALA183-VAL203
H	ALA183-VAL203
I	ALA183-VAL203

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