Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004096 | molecular_function | catalase activity |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0020037 | molecular_function | heme binding |
| A | 0042744 | biological_process | hydrogen peroxide catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070301 | biological_process | cellular response to hydrogen peroxide |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0004096 | molecular_function | catalase activity |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006979 | biological_process | response to oxidative stress |
| B | 0020037 | molecular_function | heme binding |
| B | 0042744 | biological_process | hydrogen peroxide catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0070301 | biological_process | cellular response to hydrogen peroxide |
| B | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | binding site for residue HEM A 801 |
| Chain | Residue |
| A | GLY104 |
| A | HIS279 |
| A | GLY282 |
| A | LYS283 |
| A | THR284 |
| A | HIS285 |
| A | THR323 |
| A | SER324 |
| A | TRP330 |
| A | LEU386 |
| A | THR388 |
| A | LEU105 |
| A | PHE416 |
| A | TRP420 |
| A | HOH964 |
| A | HOH1033 |
| A | HOH1124 |
| A | HOH1265 |
| A | ILE107 |
| A | ARG108 |
| A | TRP111 |
| A | VAL239 |
| A | PRO241 |
| A | LEU274 |
| A | GLY278 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 802 |
| Chain | Residue |
| A | GLY122 |
| A | ARG123 |
| A | GLY124 |
| A | SER494 |
| A | HOH1110 |
| A | HOH1241 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 803 |
| Chain | Residue |
| A | GLY63 |
| B | LYS727 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue PO4 A 804 |
| Chain | Residue |
| A | HIS381 |
| A | ARG382 |
| A | HOH909 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue MPD A 805 |
| Chain | Residue |
| A | THR323 |
| A | HOH1235 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue MPD A 806 |
| Chain | Residue |
| A | ASP83 |
| A | HOH1266 |
| site_id | AC7 |
| Number of Residues | 24 |
| Details | binding site for residue HEM B 801 |
| Chain | Residue |
| B | GLY104 |
| B | LEU105 |
| B | ILE107 |
| B | ARG108 |
| B | TRP111 |
| B | VAL239 |
| B | ILE257 |
| B | LEU274 |
| B | GLY278 |
| B | HIS279 |
| B | GLY282 |
| B | LYS283 |
| B | THR284 |
| B | HIS285 |
| B | THR323 |
| B | SER324 |
| B | LEU386 |
| B | THR388 |
| B | TRP420 |
| B | OXY803 |
| B | HOH925 |
| B | HOH997 |
| B | HOH1146 |
| B | HOH1155 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 802 |
| Chain | Residue |
| B | GLY122 |
| B | ARG123 |
| B | GLY124 |
| B | SER494 |
| B | HOH960 |
| B | HOH1300 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue OXY B 803 |
| Chain | Residue |
| B | ARG108 |
| B | HIS112 |
| B | ASP141 |
| B | HEM801 |
| B | HOH1052 |
| B | HOH1146 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue MPD B 804 |
| Chain | Residue |
| B | VAL293 |
| B | THR323 |
| B | SER324 |
| B | HOH1227 |
Functional Information from PROSITE/UniProt
| site_id | PS00435 |
| Number of Residues | 11 |
| Details | PEROXIDASE_1 Peroxidases proximal heme-ligand signature. TVALIAGGHTF |
| Chain | Residue | Details |
| A | THR271-PHE281 | |
| site_id | PS00436 |
| Number of Residues | 12 |
| Details | PEROXIDASE_2 Peroxidases active site signature. GGlfIRMaWHSA |
| Chain | Residue | Details |
| A | GLY103-ALA114 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | HIS112 | |
| B | HIS112 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: axial binding residue |
| Chain | Residue | Details |
| A | HIS279 | |
| B | HIS279 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Transition state stabilizer |
| Chain | Residue | Details |
| A | ARG108 | |
| B | ARG108 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | CROSSLNK: Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-244) |
| Chain | Residue | Details |
| A | TRP111 | |
| B | TRP111 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | CROSSLNK: Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-91) |
| Chain | Residue | Details |
| A | TYR238 | |
| A | MET264 | |
| B | TYR238 | |
| B | MET264 | |
