6MO4

Co-Crystal structure of P. aeruginosa LpxC-50067 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005737	cellular_component	cytoplasm
A	0006629	biological_process	lipid metabolic process
A	0009245	biological_process	lipid A biosynthetic process
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
A	0103117	molecular_function	UDP-3-O-acyl-N-acetylglucosamine deacetylase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue MG A 301

Chain	Residue
A	HIS78
A	HIS237
A	ASP241
A	JWM302

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site_id	AC2
Number of Residues	16
Details	binding site for residue JWM A 302

Chain	Residue
A	PHE191
A	ILE197
A	ALA206
A	GLY209
A	HIS237
A	ASP241
A	HIS264
A	MG301
A	HOH449
A	HOH464
A	HOH482
A	HIS19
A	MET62
A	GLU77
A	HIS78
A	THR190

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00388

Chain	Residue	Details
A	HIS264

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00388

Chain	Residue	Details
A	HIS78
A	HIS237
A	ASP241

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