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6MO2

Structure of dengue virus protease with an allosteric Inhibitor that blocks replication

Functional Information from GO Data
ChainGOidnamespacecontents
A0003723molecular_functionRNA binding
A0003724molecular_functionRNA helicase activity
A0004252molecular_functionserine-type endopeptidase activity
A0005524molecular_functionATP binding
A0044423cellular_componentvirion component
B0003723molecular_functionRNA binding
B0003724molecular_functionRNA helicase activity
B0004252molecular_functionserine-type endopeptidase activity
B0005524molecular_functionATP binding
B0044423cellular_componentvirion component
Functional Information from PDB Data
site_idAC1
Number of Residues9
Detailsbinding site for residue JVM A 1201
ChainResidue
AVAL1072
ALYS1073
ALYS1074
AASP1075
ALEU1076
ATHR1120
ALEU1149
AGLY1151
AILE1165

site_idAC2
Number of Residues7
Detailsbinding site for residue JVM B 1201
ChainResidue
BARG1054
BLYS1073
BLYS1074
BASP1075
BLEU1149
BGLY1151
BILE1165

219140

PDB entries from 2024-05-01

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