6MKG

Crystal structure of penicillin binding protein 5 (PBP5) from Enterococcus faecium in the benzylpenicilin-bound form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0008658	molecular_function	penicillin binding
A	0046677	biological_process	response to antibiotic
A	0071555	biological_process	cell wall organization
A	0071972	molecular_function	peptidoglycan L,D-transpeptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue PNM A 701

Chain	Residue
A	SER422
A	ASP659
A	VAL465
A	SER480
A	ASN482
A	THR618
A	GLY619
A	THR620
A	GLU622
A	GLU633

---

site_id	AC2
Number of Residues	3
Details	binding site for residue SO4 A 702

Chain	Residue
A	GLY582
A	GLU583
A	THR584

---

site_id	AC3
Number of Residues	2
Details	binding site for residue SO4 A 703

Chain	Residue
A	SER79
A	GLU80

---

site_id	AC4
Number of Residues	4
Details	binding site for residue SO4 A 704

Chain	Residue
A	SER606
A	SER661
A	THR663
A	LYS664

---

site_id	AC5
Number of Residues	3
Details	binding site for residue SO4 A 705

Chain	Residue
A	SER102
A	ASN103
A	LEU104

---

site_id	AC6
Number of Residues	2
Details	binding site for residue SO4 A 706

Chain	Residue
A	GLU508
A	ASP509

---

site_id	AC7
Number of Residues	1
Details	binding site for residue SO4 A 707

Chain	Residue
A	THR574

---

site_id	AC8
Number of Residues	2
Details	binding site for residue SO4 A 708

Chain	Residue
A	ARG179
A	ASN180

---

site_id	AC9
Number of Residues	1
Details	binding site for residue SO4 A 709

Chain	Residue
A	ARG312

---

site_id	AD1
Number of Residues	4
Details	binding site for residue SO4 A 710

Chain	Residue
A	GLY493
A	GLU494
A	LYS495
A	HOH807

---

site_id	AD2
Number of Residues	3
Details	binding site for residue SO4 A 711

Chain	Residue
A	VAL590
A	PRO591
A	ARG594

---

site_id	AD3
Number of Residues	3
Details	binding site for residue SO4 A 712

Chain	Residue
A	SER301
A	GLY302
A	HOH809

---

site_id	AD4
Number of Residues	3
Details	binding site for residue SO4 A 713

Chain	Residue
A	LYS86
A	ASN89
A	GLU284

---

site_id	AD5
Number of Residues	1
Details	binding site for residue SO4 A 714

Chain	Residue
A	TRP451

---

site_id	AD6
Number of Residues	2
Details	binding site for residue SO4 A 715

Chain	Residue
A	SER469
A	GLN470

---

site_id	AD7
Number of Residues	3
Details	binding site for residue SO4 A 716

Chain	Residue
A	GLY448
A	LEU449
A	LYS450

---

site_id	AD8
Number of Residues	2
Details	binding site for residue SO4 A 717

Chain	Residue
A	LYS572
A	GLU573

---

site_id	AD9
Number of Residues	2
Details	binding site for residue SO4 A 718

Chain	Residue
A	ASP472
A	LYS474

---

site_id	AE1
Number of Residues	1
Details	binding site for residue SO4 A 719

Chain	Residue
A	ASN339

---

site_id	AE2
Number of Residues	2
Details	binding site for residue SO4 A 720

Chain	Residue
A	ASN644
A	GLN678

---

site_id	AE3
Number of Residues	2
Details	binding site for residue SO4 A 721

Chain	Residue
A	LYS577
A	LYS578

---

site_id	AE4
Number of Residues	3
Details	binding site for residue SO4 A 722

Chain	Residue
A	SER395
A	GLN396
A	GLU397

---

site_id	AE5
Number of Residues	3
Details	binding site for residue SO4 A 723

Chain	Residue
A	ASN161
A	HOH802
A	HOH804

---

site_id	AE6
Number of Residues	4
Details	binding site for residue SO4 A 724

Chain	Residue
A	ASN62
A	LYS63
A	GLU66
A	GLU66

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