6MJG

Structure of dbOphMA in Complex with SAH and Methylated Peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008168	molecular_function	methyltransferase activity
A	0032259	biological_process	methylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	23
Details	binding site for residue SAH A 500

Chain	Residue
A	ILE18
A	PHE170
A	GLN171
A	TYR210
A	ILE211
A	ALA212
A	MET214
A	GLY241
A	VAL242
A	SER243
A	THR244
A	TYR97
A	SAR419
A	MVA421
A	HOH638
A	HOH669
A	GLY98
A	HIS99
A	VAL102
A	PHE103
A	VAL104
A	SER128
A	ALA129

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 501

Chain	Residue
A	ASP273
A	ASP273
A	HIS275
A	HIS275

---

site_id	AC3
Number of Residues	8
Details	binding site for residues MVA A 417 and IML A 418

Chain	Residue
A	TYR62
A	ASN181
A	PHE182
A	GLY184
A	PHE185
A	ARG371
A	SAR419
A	SER420

---

site_id	AC4
Number of Residues	12
Details	binding site for residues IML A 418 and SAR A 419

Chain	Residue
A	ILE43
A	TYR62
A	TYR97
A	ASN181
A	PHE182
A	GLY184
A	PHE185
A	GLY241
A	MVA417
A	SER420
A	MVA421
A	SAH500

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:A0A2R2JFI5

Chain	Residue	Details
A	ARG71
A	TYR75
A	TYR97

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250|UniProtKB:A0A2R2JFI5

Chain	Residue	Details
A	TYR97

---

site_id	SWS_FT_FI3
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:30204409, ECO:0007744|PDB:6MJF, ECO:0007744|PDB:6MJG

Chain	Residue	Details
A	HIS99
A	ALA129
A	GLN171
A	ALA212
A	THR244

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:30204409, ECO:0007744|PDB:6MJF

Chain	Residue	Details
A	VAL102
A	SER243

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	MOD_RES: N-methylvaline => ECO:0000269|PubMed:33574430

Chain	Residue	Details
A	VAL409
A	VAL411
A	VAL415
A	MVA421

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: N-methylthreonine => ECO:0000269|PubMed:33574430

Chain	Residue	Details
A	THR412

---

site_id	SWS_FT_FI7
Number of Residues	3
Details	MOD_RES: N-methylglycine => ECO:0000269|PubMed:33574430

Chain	Residue	Details
A	GLY413
A	GLY416
A	SAR419

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	MOD_RES: N-methylisoleucine => ECO:0000269|PubMed:33574430

Chain	Residue	Details
A	ILE414
A	IML418

---