6MJF

Catalytic Domain of dbOphMA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008168	molecular_function	methyltransferase activity
A	0032259	biological_process	methylation
B	0008168	molecular_function	methyltransferase activity
B	0032259	biological_process	methylation
C	0008168	molecular_function	methyltransferase activity
C	0032259	biological_process	methylation
D	0008168	molecular_function	methyltransferase activity
D	0032259	biological_process	methylation
E	0008168	molecular_function	methyltransferase activity
E	0032259	biological_process	methylation
F	0008168	molecular_function	methyltransferase activity
F	0032259	biological_process	methylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	binding site for residue SAH A 500

Chain	Residue
A	ILE18
A	PHE170
A	GLN171
A	ILE211
A	ALA212
A	GLY241
A	VAL242
A	SER243
A	THR244
A	HOH665
A	HOH678
A	TYR97
A	GLY98
A	HIS99
A	VAL102
A	PHE103
A	VAL104
A	SER128
A	ALA129

---

site_id	AC2
Number of Residues	21
Details	binding site for residue SAH B 500

Chain	Residue
B	ILE18
B	TYR97
B	GLY98
B	HIS99
B	VAL102
B	PHE103
B	VAL104
B	SER128
B	ALA129
B	PHE170
B	GLN171
B	TYR210
B	ILE211
B	ALA212
B	GLY241
B	VAL242
B	SER243
B	THR244
B	HOH649
B	HOH652
B	HOH685

---

site_id	AC3
Number of Residues	21
Details	binding site for residue SAH C 500

Chain	Residue
C	ILE18
C	TYR97
C	GLY98
C	HIS99
C	VAL102
C	PHE103
C	VAL104
C	SER128
C	ALA129
C	PHE170
C	GLN171
C	TYR210
C	ILE211
C	ALA212
C	GLY241
C	VAL242
C	SER243
C	THR244
C	HOH634
C	HOH650
C	HOH683

---

site_id	AC4
Number of Residues	21
Details	binding site for residue SAH D 500

Chain	Residue
D	ILE18
D	TYR97
D	GLY98
D	HIS99
D	VAL102
D	PHE103
D	VAL104
D	SER128
D	ALA129
D	PHE170
D	GLN171
D	TYR210
D	ILE211
D	ALA212
D	MET214
D	GLY241
D	VAL242
D	SER243
D	THR244
D	HOH638
D	HOH644

---

site_id	AC5
Number of Residues	19
Details	binding site for residue SAH F 500

Chain	Residue
F	THR244
F	HOH627
F	TYR97
F	GLY98
F	HIS99
F	VAL102
F	PHE103
F	VAL104
F	SER128
F	ALA129
F	PHE170
F	GLN171
F	TYR210
F	ILE211
F	ALA212
F	MET214
F	GLY241
F	VAL242
F	SER243

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:A0A2R2JFI5

Chain	Residue	Details
A	ARG71
D	ARG71
D	TYR75
D	TYR97
E	ARG71
E	TYR75
E	TYR97
F	ARG71
F	TYR75
F	TYR97
A	TYR75
A	TYR97
B	ARG71
B	TYR75
B	TYR97
C	ARG71
C	TYR75
C	TYR97

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000250|UniProtKB:A0A2R2JFI5

Chain	Residue	Details
A	TYR97
B	TYR97
C	TYR97
D	TYR97
E	TYR97
F	TYR97

---

site_id	SWS_FT_FI3
Number of Residues	30
Details	BINDING: BINDING => ECO:0000269|PubMed:30204409, ECO:0007744|PDB:6MJF, ECO:0007744|PDB:6MJG

Chain	Residue	Details
A	HIS99
B	THR244
C	HIS99
C	ALA129
C	GLN171
C	ALA212
C	THR244
D	HIS99
D	ALA129
D	GLN171
D	ALA212
A	ALA129
D	THR244
E	HIS99
E	ALA129
E	GLN171
E	ALA212
E	THR244
F	HIS99
F	ALA129
F	GLN171
F	ALA212
A	GLN171
F	THR244
A	ALA212
A	THR244
B	HIS99
B	ALA129
B	GLN171
B	ALA212

---

site_id	SWS_FT_FI4
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:30204409, ECO:0007744|PDB:6MJF

Chain	Residue	Details
A	VAL102
E	SER243
F	VAL102
F	SER243
A	SER243
B	VAL102
B	SER243
C	VAL102
C	SER243
D	VAL102
D	SER243
E	VAL102

---