6MIL

Crystal structure of AF9 YEATS domain in complex with histone H3K9bu

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000786	cellular_component	nucleosome
B	0003677	molecular_function	DNA binding
B	0030527	molecular_function	structural constituent of chromatin
D	0000786	cellular_component	nucleosome
D	0003677	molecular_function	DNA binding
D	0030527	molecular_function	structural constituent of chromatin

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue PEG A 201

Chain	Residue
A	HOH378
C	HIS54
C	GLU86

---

site_id	AC2
Number of Residues	2
Details	binding site for residue MLI C 201

Chain	Residue
C	ARG118
C	GLU120

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	274
Details	Domain: {"description":"YEATS","evidences":[{"source":"PROSITE-ProRule","id":"PRU00376","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Region: {"description":"Histone H3K9cr binding","evidences":[{"source":"PubMed","id":"27105114","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30385749","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5HJB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HJD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MIM","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	4
Details	Site: {"description":"Histone H3K9cr binding","evidences":[{"source":"PubMed","id":"27105114","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30385749","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5HJB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HJD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MIL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6MIM","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"16267050","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16457588","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17194708","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"5-glutamyl serotonin; alternate","evidences":[{"source":"PubMed","id":"30867594","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine; by PKC","evidences":[{"source":"PubMed","id":"20228790","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI7
Number of Residues	2
Details	Modified residue: {"description":"Symmetric dimethylarginine; by PRMT5; alternate","evidences":[{"source":"UniProtKB","id":"P68433","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI8
Number of Residues	2
Details	Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"11242053","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16185088","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16267050","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16457588","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17194708","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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