6MI8

Cryo-EM Structure of vanadate-trapped E.coli LptB2FGC

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0015920	biological_process	lipopolysaccharide transport
A	0016020	cellular_component	membrane
A	0016887	molecular_function	ATP hydrolysis activity
A	0043165	biological_process	Gram-negative-bacterium-type cell outer membrane assembly
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0055085	biological_process	transmembrane transport
A	1990351	cellular_component	transporter complex
B	0000166	molecular_function	nucleotide binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005886	cellular_component	plasma membrane
B	0015920	biological_process	lipopolysaccharide transport
B	0016020	cellular_component	membrane
B	0016887	molecular_function	ATP hydrolysis activity
B	0043165	biological_process	Gram-negative-bacterium-type cell outer membrane assembly
B	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
B	0055085	biological_process	transmembrane transport
B	1990351	cellular_component	transporter complex
F	0005515	molecular_function	protein binding
F	0005886	cellular_component	plasma membrane
F	0015920	biological_process	lipopolysaccharide transport
F	0016020	cellular_component	membrane
F	0043165	biological_process	Gram-negative-bacterium-type cell outer membrane assembly
F	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
F	0055085	biological_process	transmembrane transport
F	1990351	cellular_component	transporter complex
G	0005515	molecular_function	protein binding
G	0005886	cellular_component	plasma membrane
G	0015920	biological_process	lipopolysaccharide transport
G	0016020	cellular_component	membrane
G	0043165	biological_process	Gram-negative-bacterium-type cell outer membrane assembly
G	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
G	0055085	biological_process	transmembrane transport
G	1990351	cellular_component	transporter complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	binding site for residue AOV A 301

Chain	Residue
A	PRO37
A	HIS195
B	LEU130
B	SER137
B	SER139
B	GLY140
B	GLY141
B	GLU142
B	GLY167
G	SER302
A	ASN38
A	GLY39
A	GLY41
A	LYS42
A	THR43
A	THR44
A	GLN85
A	GLU163

---

site_id	AC2
Number of Residues	15
Details	binding site for residue AOV B 301

Chain	Residue
A	SER137
A	SER139
A	GLY140
A	GLY141
A	GLY167
B	ASN38
B	GLY39
B	ALA40
B	GLY41
B	LYS42
B	THR43
B	THR44
B	GLN85
B	GLU163
B	HIS195

---

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGERRRVEIARAL

Chain	Residue	Details
A	LEU138-LEU152

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	220
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	27
Details	Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	61
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---