Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue JE4 A 601 |
| Chain | Residue |
| A | ARG111 |
| A | PRO491 |
| A | GLN495 |
| A | HOH734 |
| A | HOH783 |
| A | PHE113 |
| A | LEU216 |
| A | THR218 |
| A | THR219 |
| A | GLU249 |
| A | GLU250 |
| A | THR253 |
| A | GLN257 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 A 602 |
| Chain | Residue |
| A | ARG32 |
| A | SER34 |
| A | LYS35 |
| A | SER36 |
| A | THR42 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 A 603 |
| Chain | Residue |
| A | ASN410 |
| A | THR411 |
| A | GLU412 |
| A | ARG413 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | binding site for residue JE4 B 601 |
| Chain | Residue |
| B | ARG111 |
| B | PHE113 |
| B | HIS114 |
| B | THR218 |
| B | GLU249 |
| B | GLU250 |
| B | THR253 |
| B | LEU254 |
| B | GLN257 |
| B | PRO491 |
| B | LYS492 |
| B | GLN495 |
| B | HOH753 |
| B | HOH916 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue PO4 B 602 |
| Chain | Residue |
| B | ARG32 |
| B | SER34 |
| B | LYS35 |
| B | SER36 |
| B | THR42 |
| B | MET311 |
| B | HOH816 |
Functional Information from PROSITE/UniProt
| site_id | PS00383 |
| Number of Residues | 11 |
| Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGigRTG |
| Chain | Residue | Details |
| A | VAL457-GLY467 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Phosphocysteine intermediate"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P35235","evidenceCode":"ECO:0000250"}]} |
