6MB4

Binary (sisomicin) structure of AAC-IIIb

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008080	molecular_function	N-acetyltransferase activity
A	0046353	molecular_function	aminoglycoside 3-N-acetyltransferase activity
A	0046677	biological_process	response to antibiotic
B	0008080	molecular_function	N-acetyltransferase activity
B	0046353	molecular_function	aminoglycoside 3-N-acetyltransferase activity
B	0046677	biological_process	response to antibiotic
C	0008080	molecular_function	N-acetyltransferase activity
C	0046353	molecular_function	aminoglycoside 3-N-acetyltransferase activity
C	0046677	biological_process	response to antibiotic
D	0008080	molecular_function	N-acetyltransferase activity
D	0046353	molecular_function	aminoglycoside 3-N-acetyltransferase activity
D	0046677	biological_process	response to antibiotic

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	binding site for residue SIS B 301

Chain	Residue
B	TYR65
B	THR213
B	GLY214
B	HOH402
B	HOH415
B	HOH443
B	HOH486
B	HOH500
B	HOH506
B	HOH517
C	TRP25
B	ASP67
B	TRP68
B	GLU73
B	GLY124
B	TYR147
B	ASP171
B	HIS177
B	LYS191

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