6MAY
Crystal structure of N-myristoyl transferase (NMT) G386E mutant from Plasmodium vivax
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004379 | molecular_function | glycylpeptide N-tetradecanoyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006499 | biological_process | N-terminal protein myristoylation |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0018008 | biological_process | N-terminal peptidyl-glycine N-myristoylation |
| B | 0004379 | molecular_function | glycylpeptide N-tetradecanoyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006499 | biological_process | N-terminal protein myristoylation |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0018008 | biological_process | N-terminal peptidyl-glycine N-myristoylation |
| C | 0004379 | molecular_function | glycylpeptide N-tetradecanoyltransferase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006499 | biological_process | N-terminal protein myristoylation |
| C | 0016746 | molecular_function | acyltransferase activity |
| C | 0018008 | biological_process | N-terminal peptidyl-glycine N-myristoylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 36 |
| Details | binding site for residue YNC A 501 |
| Chain | Residue |
| A | TYR28 |
| A | LEU163 |
| A | CYS164 |
| A | VAL165 |
| A | ARG170 |
| A | SER171 |
| A | LYS172 |
| A | ARG173 |
| A | LEU174 |
| A | ALA175 |
| A | PRO176 |
| A | LYS29 |
| A | THR183 |
| A | ILE186 |
| A | TRP192 |
| A | ALA194 |
| A | TYR196 |
| A | THR197 |
| A | LEU202 |
| A | TYR393 |
| A | HOH635 |
| A | HOH643 |
| A | PHE30 |
| A | HOH686 |
| A | HOH730 |
| A | HOH738 |
| A | HOH786 |
| A | HOH862 |
| A | HOH895 |
| A | HOH908 |
| A | TRP31 |
| A | ASN94 |
| A | TYR95 |
| A | VAL96 |
| A | ASN161 |
| A | PHE162 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 502 |
| Chain | Residue |
| A | LYS180 |
| A | THR247 |
| A | LEU248 |
| A | ARG358 |
| A | HOH670 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | GLU159 |
| A | TYR337 |
| A | VAL408 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 504 |
| Chain | Residue |
| A | ARG210 |
| A | LYS373 |
| C | ARG210 |
| C | LYS373 |
| site_id | AC5 |
| Number of Residues | 32 |
| Details | binding site for residue YNC B 501 |
| Chain | Residue |
| B | TYR28 |
| B | LYS29 |
| B | PHE30 |
| B | TRP31 |
| B | ASN94 |
| B | TYR95 |
| B | VAL96 |
| B | ASN161 |
| B | PHE162 |
| B | LEU163 |
| B | CYS164 |
| B | VAL165 |
| B | ARG170 |
| B | SER171 |
| B | ARG173 |
| B | LEU174 |
| B | ALA175 |
| B | PRO176 |
| B | THR183 |
| B | ILE186 |
| B | TRP192 |
| B | GLN193 |
| B | ALA194 |
| B | TYR196 |
| B | THR197 |
| B | LEU202 |
| B | TYR393 |
| B | HOH609 |
| B | HOH610 |
| B | HOH613 |
| B | HOH623 |
| B | HOH741 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 502 |
| Chain | Residue |
| B | LYS180 |
| B | THR247 |
| B | LEU248 |
| B | ARG358 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| B | GLU159 |
| B | PHE281 |
| B | TRP289 |
| B | TYR337 |
| B | ILE407 |
| B | VAL408 |
| B | LEU409 |
| B | LEU410 |
| B | HOH601 |
| site_id | AC8 |
| Number of Residues | 27 |
| Details | binding site for residue YNC C 501 |
| Chain | Residue |
| C | VAL96 |
| C | PHE162 |
| C | LEU163 |
| C | CYS164 |
| C | VAL165 |
| C | ARG170 |
| C | ARG173 |
| C | LEU174 |
| C | ALA175 |
| C | PRO176 |
| C | THR183 |
| C | ILE186 |
| C | TRP192 |
| C | TYR196 |
| C | THR197 |
| C | TYR393 |
| C | HOH614 |
| C | HOH625 |
| C | HOH729 |
| C | HOH785 |
| C | HOH821 |
| C | TYR28 |
| C | LYS29 |
| C | PHE30 |
| C | TRP31 |
| C | ASN94 |
| C | TYR95 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue CL C 502 |
| Chain | Residue |
| C | LYS180 |
| C | THR247 |
| C | LEU248 |
| C | ARG358 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue EDO C 503 |
| Chain | Residue |
| C | PRO50 |
| C | ILE52 |
| C | SER53 |
| C | ASP54 |
| C | ASN55 |
| C | TRP192 |
| C | GLN193 |
| C | HOH770 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 504 |
| Chain | Residue |
| C | GLU159 |
| C | TRP289 |
| C | TYR337 |
| C | VAL408 |
| C | LEU409 |
| C | LEU410 |
| C | HOH749 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 C 505 |
| Chain | Residue |
| C | ASN120 |
| C | LYS257 |
| C | LYS259 |
| C | HOH605 |
| C | HOH663 |
| C | HOH766 |
Functional Information from PROSITE/UniProt
| site_id | PS00975 |
| Number of Residues | 9 |
| Details | NMT_1 Myristoyl-CoA:protein N-myristoyltransferase signature 1. EVNFLCvHK |
| Chain | Residue | Details |
| A | GLU159-LYS167 |
