Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 7 |
Details | binding site for residue IPA A 301 |
Chain | Residue |
A | ASP263 |
A | SER267 |
B | TYR31 |
B | LYS36 |
B | ASP275 |
B | SER278 |
B | EDO304 |
site_id | AC2 |
Number of Residues | 6 |
Details | binding site for residue IPA A 302 |
Chain | Residue |
A | LYS204 |
A | THR227 |
A | ILE228 |
A | SER229 |
A | THR179 |
A | ALA180 |
site_id | AC3 |
Number of Residues | 8 |
Details | binding site for residue MES A 303 |
Chain | Residue |
A | THR146 |
A | ARG147 |
A | ASN150 |
B | THR99 |
B | GLN107 |
B | LEU111 |
B | GLN114 |
B | EDO309 |
site_id | AC4 |
Number of Residues | 8 |
Details | binding site for residue EDO A 304 |
Chain | Residue |
A | MET208 |
A | SER211 |
A | ARG212 |
A | THR227 |
A | GLY282 |
A | THR283 |
A | ASP284 |
A | HOH403 |
site_id | AC5 |
Number of Residues | 7 |
Details | binding site for residue EDO A 305 |
Chain | Residue |
A | ASN150 |
A | LEU153 |
A | ASN154 |
A | TYR157 |
A | EDO306 |
B | PRO74 |
B | SER75 |
site_id | AC6 |
Number of Residues | 7 |
Details | binding site for residue EDO A 306 |
Chain | Residue |
A | TYR157 |
A | ALA206 |
A | GLU209 |
A | HIS210 |
A | EDO305 |
A | EDO310 |
B | SER75 |
site_id | AC7 |
Number of Residues | 4 |
Details | binding site for residue EDO A 307 |
Chain | Residue |
A | LYS204 |
A | ARG286 |
A | ASP288 |
A | TYR291 |
site_id | AC8 |
Number of Residues | 5 |
Details | binding site for residue EDO A 308 |
Chain | Residue |
A | THR47 |
A | GLY48 |
A | LEU73 |
A | CYS100 |
A | EDO309 |
site_id | AC9 |
Number of Residues | 7 |
Details | binding site for residue EDO A 309 |
Chain | Residue |
A | THR47 |
A | ALA129 |
A | THR156 |
A | THR159 |
A | EDO308 |
A | HOH401 |
A | HOH412 |
site_id | AD1 |
Number of Residues | 5 |
Details | binding site for residue EDO A 310 |
Chain | Residue |
A | HIS210 |
A | EDO306 |
A | EDO313 |
A | PEG316 |
B | SER75 |
site_id | AD2 |
Number of Residues | 4 |
Details | binding site for residue EDO A 311 |
Chain | Residue |
A | SER38 |
A | ARG40 |
A | GLN63 |
A | ALA64 |
site_id | AD3 |
Number of Residues | 4 |
Details | binding site for residue EDO A 312 |
Chain | Residue |
A | GLU142 |
A | TYR232 |
A | VAL253 |
A | TYR291 |
site_id | AD4 |
Number of Residues | 6 |
Details | binding site for residue EDO A 313 |
Chain | Residue |
A | TYR157 |
A | ARG161 |
A | HIS164 |
A | HIS210 |
A | LEU214 |
A | EDO310 |
site_id | AD5 |
Number of Residues | 8 |
Details | binding site for residue PGE A 314 |
Chain | Residue |
A | GLU77 |
A | ALA97 |
A | LEU98 |
A | THR99 |
A | GLN107 |
A | GLU110 |
A | LEU111 |
A | GLN114 |
site_id | AD6 |
Number of Residues | 4 |
Details | binding site for residue PEG A 315 |
Chain | Residue |
A | ALA202 |
A | ALA206 |
A | GLU209 |
A | HOH429 |
site_id | AD7 |
Number of Residues | 10 |
Details | binding site for residue PEG A 316 |
Chain | Residue |
B | LYS79 |
A | ASN154 |
A | ARG158 |
A | ARG161 |
A | EDO310 |
A | HOH408 |
B | SER75 |
B | GLN76 |
B | GLU77 |
B | ASP78 |
site_id | AD8 |
Number of Residues | 7 |
Details | binding site for residue PEG A 317 |
Chain | Residue |
A | GLY48 |
A | GLY51 |
A | ASP72 |
A | ASN128 |
A | SER181 |
A | HOH402 |
A | HOH425 |
site_id | AD9 |
Number of Residues | 3 |
Details | binding site for residue PEG A 318 |
Chain | Residue |
A | ALA109 |
A | LYS112 |
A | THR113 |
site_id | AE1 |
Number of Residues | 5 |
Details | binding site for residue IPA B 301 |
Chain | Residue |
B | ARG42 |
B | GLY174 |
B | GLY222 |
B | ARG224 |
B | ASP275 |
site_id | AE2 |
Number of Residues | 9 |
Details | binding site for residue EDO B 302 |
Chain | Residue |
B | MET208 |
B | SER211 |
B | ARG212 |
B | SER225 |
B | ASN226 |
B | THR227 |
B | GLY282 |
B | THR283 |
B | ASP284 |
site_id | AE3 |
Number of Residues | 4 |
Details | binding site for residue EDO B 303 |
Chain | Residue |
B | ASP67 |
B | GLY92 |
B | THR93 |
B | PGE312 |
site_id | AE4 |
Number of Residues | 6 |
Details | binding site for residue EDO B 304 |
Chain | Residue |
A | ASP263 |
A | IPA301 |
B | LYS25 |
B | LYS36 |
B | ASP275 |
B | SER278 |
site_id | AE5 |
Number of Residues | 7 |
Details | binding site for residue EDO B 305 |
Chain | Residue |
B | THR179 |
B | ALA180 |
B | TYR200 |
B | LYS204 |
B | MET208 |
B | ILE228 |
B | SER229 |
site_id | AE6 |
Number of Residues | 4 |
Details | binding site for residue EDO B 306 |
Chain | Residue |
B | ASP35 |
B | SER38 |
B | ARG40 |
B | ASP275 |
site_id | AE7 |
Number of Residues | 6 |
Details | binding site for residue EDO B 307 |
Chain | Residue |
B | GLY48 |
B | ASP72 |
B | CYS100 |
B | ASP101 |
B | VAL102 |
B | HOH435 |
site_id | AE8 |
Number of Residues | 4 |
Details | binding site for residue EDO B 308 |
Chain | Residue |
B | PRO22 |
B | LEU23 |
B | ASP24 |
B | HOH460 |
site_id | AE9 |
Number of Residues | 4 |
Details | binding site for residue EDO B 309 |
Chain | Residue |
A | MES303 |
B | PRO74 |
B | GLU77 |
B | THR99 |
site_id | AF1 |
Number of Residues | 3 |
Details | binding site for residue EDO B 310 |
Chain | Residue |
B | LYS43 |
B | LEU119 |
B | GLY120 |
site_id | AF2 |
Number of Residues | 11 |
Details | binding site for residue PG4 B 311 |
Chain | Residue |
A | GLN63 |
A | ARG90 |
A | PHE91 |
B | ASP28 |
B | SER29 |
B | SER29 |
B | ASN30 |
B | ASN30 |
B | TYR31 |
B | SER32 |
B | ASP35 |
site_id | AF3 |
Number of Residues | 7 |
Details | binding site for residue PGE B 312 |
Chain | Residue |
B | ARG40 |
B | GLY41 |
B | ARG42 |
B | GLY65 |
B | ASP67 |
B | EDO303 |
B | HOH434 |
site_id | AF4 |
Number of Residues | 1 |
Details | binding site for residue PEG B 313 |
site_id | AF5 |
Number of Residues | 2 |
Details | binding site for residue CL B 314 |
Chain | Residue |
B | THR47 |
B | THR156 |
site_id | AF6 |
Number of Residues | 4 |
Details | binding site for residue IMD B 315 |
Chain | Residue |
B | GLU209 |
B | GLU209 |
B | HIS210 |
B | HIS210 |
site_id | AF7 |
Number of Residues | 3 |
Details | binding site for residue IMD B 316 |
Chain | Residue |
B | ALA217 |
B | ALA217 |
B | LEU218 |