Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue IPA A 301 |
| Chain | Residue |
| A | ASP263 |
| A | SER267 |
| B | TYR31 |
| B | LYS36 |
| B | ASP275 |
| B | SER278 |
| B | EDO304 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue IPA A 302 |
| Chain | Residue |
| A | LYS204 |
| A | THR227 |
| A | ILE228 |
| A | SER229 |
| A | THR179 |
| A | ALA180 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue MES A 303 |
| Chain | Residue |
| A | THR146 |
| A | ARG147 |
| A | ASN150 |
| B | THR99 |
| B | GLN107 |
| B | LEU111 |
| B | GLN114 |
| B | EDO309 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | MET208 |
| A | SER211 |
| A | ARG212 |
| A | THR227 |
| A | GLY282 |
| A | THR283 |
| A | ASP284 |
| A | HOH403 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | ASN150 |
| A | LEU153 |
| A | ASN154 |
| A | TYR157 |
| A | EDO306 |
| B | PRO74 |
| B | SER75 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | TYR157 |
| A | ALA206 |
| A | GLU209 |
| A | HIS210 |
| A | EDO305 |
| A | EDO310 |
| B | SER75 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | LYS204 |
| A | ARG286 |
| A | ASP288 |
| A | TYR291 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 308 |
| Chain | Residue |
| A | THR47 |
| A | GLY48 |
| A | LEU73 |
| A | CYS100 |
| A | EDO309 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 309 |
| Chain | Residue |
| A | THR47 |
| A | ALA129 |
| A | THR156 |
| A | THR159 |
| A | EDO308 |
| A | HOH401 |
| A | HOH412 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 310 |
| Chain | Residue |
| A | HIS210 |
| A | EDO306 |
| A | EDO313 |
| A | PEG316 |
| B | SER75 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 311 |
| Chain | Residue |
| A | SER38 |
| A | ARG40 |
| A | GLN63 |
| A | ALA64 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 312 |
| Chain | Residue |
| A | GLU142 |
| A | TYR232 |
| A | VAL253 |
| A | TYR291 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 313 |
| Chain | Residue |
| A | TYR157 |
| A | ARG161 |
| A | HIS164 |
| A | HIS210 |
| A | LEU214 |
| A | EDO310 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for residue PGE A 314 |
| Chain | Residue |
| A | GLU77 |
| A | ALA97 |
| A | LEU98 |
| A | THR99 |
| A | GLN107 |
| A | GLU110 |
| A | LEU111 |
| A | GLN114 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 315 |
| Chain | Residue |
| A | ALA202 |
| A | ALA206 |
| A | GLU209 |
| A | HOH429 |
| site_id | AD7 |
| Number of Residues | 10 |
| Details | binding site for residue PEG A 316 |
| Chain | Residue |
| B | LYS79 |
| A | ASN154 |
| A | ARG158 |
| A | ARG161 |
| A | EDO310 |
| A | HOH408 |
| B | SER75 |
| B | GLN76 |
| B | GLU77 |
| B | ASP78 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue PEG A 317 |
| Chain | Residue |
| A | GLY48 |
| A | GLY51 |
| A | ASP72 |
| A | ASN128 |
| A | SER181 |
| A | HOH402 |
| A | HOH425 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 318 |
| Chain | Residue |
| A | ALA109 |
| A | LYS112 |
| A | THR113 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue IPA B 301 |
| Chain | Residue |
| B | ARG42 |
| B | GLY174 |
| B | GLY222 |
| B | ARG224 |
| B | ASP275 |
| site_id | AE2 |
| Number of Residues | 9 |
| Details | binding site for residue EDO B 302 |
| Chain | Residue |
| B | MET208 |
| B | SER211 |
| B | ARG212 |
| B | SER225 |
| B | ASN226 |
| B | THR227 |
| B | GLY282 |
| B | THR283 |
| B | ASP284 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| B | ASP67 |
| B | GLY92 |
| B | THR93 |
| B | PGE312 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| A | ASP263 |
| A | IPA301 |
| B | LYS25 |
| B | LYS36 |
| B | ASP275 |
| B | SER278 |
| site_id | AE5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 305 |
| Chain | Residue |
| B | THR179 |
| B | ALA180 |
| B | TYR200 |
| B | LYS204 |
| B | MET208 |
| B | ILE228 |
| B | SER229 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 306 |
| Chain | Residue |
| B | ASP35 |
| B | SER38 |
| B | ARG40 |
| B | ASP275 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 307 |
| Chain | Residue |
| B | GLY48 |
| B | ASP72 |
| B | CYS100 |
| B | ASP101 |
| B | VAL102 |
| B | HOH435 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 308 |
| Chain | Residue |
| B | PRO22 |
| B | LEU23 |
| B | ASP24 |
| B | HOH460 |
| site_id | AE9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 309 |
| Chain | Residue |
| A | MES303 |
| B | PRO74 |
| B | GLU77 |
| B | THR99 |
| site_id | AF1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 310 |
| Chain | Residue |
| B | LYS43 |
| B | LEU119 |
| B | GLY120 |
| site_id | AF2 |
| Number of Residues | 11 |
| Details | binding site for residue PG4 B 311 |
| Chain | Residue |
| A | GLN63 |
| A | ARG90 |
| A | PHE91 |
| B | ASP28 |
| B | SER29 |
| B | SER29 |
| B | ASN30 |
| B | ASN30 |
| B | TYR31 |
| B | SER32 |
| B | ASP35 |
| site_id | AF3 |
| Number of Residues | 7 |
| Details | binding site for residue PGE B 312 |
| Chain | Residue |
| B | ARG40 |
| B | GLY41 |
| B | ARG42 |
| B | GLY65 |
| B | ASP67 |
| B | EDO303 |
| B | HOH434 |
| site_id | AF4 |
| Number of Residues | 1 |
| Details | binding site for residue PEG B 313 |
| site_id | AF5 |
| Number of Residues | 2 |
| Details | binding site for residue CL B 314 |
| Chain | Residue |
| B | THR47 |
| B | THR156 |
| site_id | AF6 |
| Number of Residues | 4 |
| Details | binding site for residue IMD B 315 |
| Chain | Residue |
| B | GLU209 |
| B | GLU209 |
| B | HIS210 |
| B | HIS210 |
| site_id | AF7 |
| Number of Residues | 3 |
| Details | binding site for residue IMD B 316 |
| Chain | Residue |
| B | ALA217 |
| B | ALA217 |
| B | LEU218 |
