Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008236 | molecular_function | serine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 401 |
| Chain | Residue |
| A | ASP328 |
| A | VAL329 |
| A | GLY344 |
| A | GLY346 |
| A | ASP348 |
| A | HOH652 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | THR186 |
| A | LEU273 |
| A | TYR275 |
| A | LEU280 |
| A | HOH501 |
| A | HOH542 |
| A | HOH544 |
| A | HOH557 |
| A | ASN9 |
| A | PHE48 |
| A | ASN52 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | ALA5 |
| A | ASN221 |
| A | GLU222 |
| A | HOH583 |
| A | HOH599 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 404 |
| Chain | Residue |
| A | ASN125 |
| A | VAL126 |
| A | ALA127 |
| A | ASN306 |
| A | HOH508 |
| A | HOH552 |
| A | HOH611 |
| A | HOH752 |
| A | HOH784 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 405 |
| Chain | Residue |
| A | TRP246 |
| A | HOH738 |
| A | HOH771 |
| A | HOH922 |
| A | HOH928 |
| site_id | AC6 |
| Number of Residues | 20 |
| Details | binding site for N-acetyl-L-isoleucyl-L-prolyl-L-Phenylalaninal chain B |
| Chain | Residue |
| A | ILE35 |
| A | GLU80 |
| A | SER133 |
| A | LEU134 |
| A | GLY135 |
| A | TRP136 |
| A | SER167 |
| A | GLY169 |
| A | ASP170 |
| A | GLU171 |
| A | ARG179 |
| A | SER190 |
| A | GLY285 |
| A | THR286 |
| A | SER287 |
| A | HOH657 |
| A | HOH732 |
| B | HOH401 |
| B | HOH402 |
| B | HOH403 |
Functional Information from PROSITE/UniProt
| site_id | PS00138 |
| Number of Residues | 11 |
| Details | SUBTILASE_SER Serine proteases, subtilase family, serine active site. GTSlAsPiFVG |
| Chain | Residue | Details |
| A | GLY285-GLY295 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLU80 | |
| A | ASP84 | |
| A | SER287 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLY344 | |
| A | GLY346 | |
| A | ASP348 | |
| A | ASP328 | |
| A | VAL329 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 380 |
| Chain | Residue | Details |
| A | GLU80 | proton shuttle (general acid/base) |
| A | ASP84 | proton shuttle (general acid/base) |
| A | ASP170 | electrostatic stabiliser |
| A | SER287 | covalent catalysis |
