6M7O

Human DNA polymerase eta ternary complex with Mn2+ and dTMPNPP oppositing cdA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MN A 501

Chain	Residue
A	ASP13
A	MET14
A	ASP115
A	MN502
A	1FZ503

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site_id	AC2
Number of Residues	7
Details	binding site for residue MN A 502

Chain	Residue
A	MN501
A	1FZ503
P	DG9
A	ASP13
A	SER113
A	ASP115
A	GLU116

---

site_id	AC3
Number of Residues	17
Details	binding site for residue 1FZ A 503

Chain	Residue
A	ASP13
A	MET14
A	ASP15
A	CYS16
A	PHE17
A	PHE18
A	ILE48
A	TYR52
A	ARG55
A	ARG61
A	ASP115
A	LYS231
A	MN501
A	MN502
P	DG9
P	HOH101
T	02I4

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO

Chain	Residue	Details
A	ASP13
A	MET14
A	ASP115
A	GLU116

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:27284197

Chain	Residue	Details
A	ARG61

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