6M61
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) with inhibitor heptelidic acid
Functional Information from GO Data
Chain | GOid | namespace | contents |
O | 0000226 | biological_process | microtubule cytoskeleton organization |
O | 0001819 | biological_process | positive regulation of cytokine production |
O | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
O | 0005515 | molecular_function | protein binding |
O | 0005634 | cellular_component | nucleus |
O | 0005737 | cellular_component | cytoplasm |
O | 0005811 | cellular_component | lipid droplet |
O | 0005829 | cellular_component | cytosol |
O | 0005856 | cellular_component | cytoskeleton |
O | 0005886 | cellular_component | plasma membrane |
O | 0006006 | biological_process | glucose metabolic process |
O | 0006096 | biological_process | glycolytic process |
O | 0006417 | biological_process | regulation of translation |
O | 0006915 | biological_process | apoptotic process |
O | 0008017 | molecular_function | microtubule binding |
O | 0010951 | biological_process | negative regulation of endopeptidase activity |
O | 0015630 | cellular_component | microtubule cytoskeleton |
O | 0016020 | cellular_component | membrane |
O | 0016241 | biological_process | regulation of macroautophagy |
O | 0016491 | molecular_function | oxidoreductase activity |
O | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
O | 0016740 | molecular_function | transferase activity |
O | 0017148 | biological_process | negative regulation of translation |
O | 0019828 | molecular_function | aspartic-type endopeptidase inhibitor activity |
O | 0031640 | biological_process | killing of cells of another organism |
O | 0031965 | cellular_component | nuclear membrane |
O | 0031982 | cellular_component | vesicle |
O | 0032481 | biological_process | positive regulation of type I interferon production |
O | 0035605 | molecular_function | peptidyl-cysteine S-nitrosylase activity |
O | 0035606 | biological_process | peptidyl-cysteine S-trans-nitrosylation |
O | 0042802 | molecular_function | identical protein binding |
O | 0043123 | biological_process | positive regulation of canonical NF-kappaB signal transduction |
O | 0043231 | cellular_component | intracellular membrane-bounded organelle |
O | 0045087 | biological_process | innate immune response |
O | 0048471 | cellular_component | perinuclear region of cytoplasm |
O | 0050661 | molecular_function | NADP binding |
O | 0050821 | biological_process | protein stabilization |
O | 0050832 | biological_process | defense response to fungus |
O | 0051287 | molecular_function | NAD binding |
O | 0051402 | biological_process | neuron apoptotic process |
O | 0051873 | biological_process | killing by host of symbiont cells |
O | 0061844 | biological_process | antimicrobial humoral immune response mediated by antimicrobial peptide |
O | 0070062 | cellular_component | extracellular exosome |
O | 0071346 | biological_process | cellular response to type II interferon |
O | 0097452 | cellular_component | GAIT complex |
O | 0097718 | molecular_function | disordered domain specific binding |
O | 1990904 | cellular_component | ribonucleoprotein complex |
P | 0000226 | biological_process | microtubule cytoskeleton organization |
P | 0001819 | biological_process | positive regulation of cytokine production |
P | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
P | 0005515 | molecular_function | protein binding |
P | 0005634 | cellular_component | nucleus |
P | 0005737 | cellular_component | cytoplasm |
P | 0005811 | cellular_component | lipid droplet |
P | 0005829 | cellular_component | cytosol |
P | 0005856 | cellular_component | cytoskeleton |
P | 0005886 | cellular_component | plasma membrane |
P | 0006006 | biological_process | glucose metabolic process |
P | 0006096 | biological_process | glycolytic process |
P | 0006417 | biological_process | regulation of translation |
P | 0006915 | biological_process | apoptotic process |
P | 0008017 | molecular_function | microtubule binding |
P | 0010951 | biological_process | negative regulation of endopeptidase activity |
P | 0015630 | cellular_component | microtubule cytoskeleton |
P | 0016020 | cellular_component | membrane |
P | 0016241 | biological_process | regulation of macroautophagy |
P | 0016491 | molecular_function | oxidoreductase activity |
P | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
P | 0016740 | molecular_function | transferase activity |
P | 0017148 | biological_process | negative regulation of translation |
P | 0019828 | molecular_function | aspartic-type endopeptidase inhibitor activity |
P | 0031640 | biological_process | killing of cells of another organism |
P | 0031965 | cellular_component | nuclear membrane |
P | 0031982 | cellular_component | vesicle |
P | 0032481 | biological_process | positive regulation of type I interferon production |
P | 0035605 | molecular_function | peptidyl-cysteine S-nitrosylase activity |
P | 0035606 | biological_process | peptidyl-cysteine S-trans-nitrosylation |
P | 0042802 | molecular_function | identical protein binding |
P | 0043123 | biological_process | positive regulation of canonical NF-kappaB signal transduction |
P | 0043231 | cellular_component | intracellular membrane-bounded organelle |
P | 0045087 | biological_process | innate immune response |
P | 0048471 | cellular_component | perinuclear region of cytoplasm |
P | 0050661 | molecular_function | NADP binding |
P | 0050821 | biological_process | protein stabilization |
P | 0050832 | biological_process | defense response to fungus |
P | 0051287 | molecular_function | NAD binding |
P | 0051402 | biological_process | neuron apoptotic process |
P | 0051873 | biological_process | killing by host of symbiont cells |
P | 0061844 | biological_process | antimicrobial humoral immune response mediated by antimicrobial peptide |
P | 0070062 | cellular_component | extracellular exosome |
P | 0071346 | biological_process | cellular response to type II interferon |
P | 0097452 | cellular_component | GAIT complex |
P | 0097718 | molecular_function | disordered domain specific binding |
P | 1990904 | cellular_component | ribonucleoprotein complex |
Q | 0000226 | biological_process | microtubule cytoskeleton organization |
Q | 0001819 | biological_process | positive regulation of cytokine production |
Q | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
Q | 0005515 | molecular_function | protein binding |
Q | 0005634 | cellular_component | nucleus |
Q | 0005737 | cellular_component | cytoplasm |
Q | 0005811 | cellular_component | lipid droplet |
Q | 0005829 | cellular_component | cytosol |
Q | 0005856 | cellular_component | cytoskeleton |
Q | 0005886 | cellular_component | plasma membrane |
Q | 0006006 | biological_process | glucose metabolic process |
Q | 0006096 | biological_process | glycolytic process |
Q | 0006417 | biological_process | regulation of translation |
Q | 0006915 | biological_process | apoptotic process |
Q | 0008017 | molecular_function | microtubule binding |
Q | 0010951 | biological_process | negative regulation of endopeptidase activity |
Q | 0015630 | cellular_component | microtubule cytoskeleton |
Q | 0016020 | cellular_component | membrane |
Q | 0016241 | biological_process | regulation of macroautophagy |
Q | 0016491 | molecular_function | oxidoreductase activity |
Q | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
Q | 0016740 | molecular_function | transferase activity |
Q | 0017148 | biological_process | negative regulation of translation |
Q | 0019828 | molecular_function | aspartic-type endopeptidase inhibitor activity |
Q | 0031640 | biological_process | killing of cells of another organism |
Q | 0031965 | cellular_component | nuclear membrane |
Q | 0031982 | cellular_component | vesicle |
Q | 0032481 | biological_process | positive regulation of type I interferon production |
Q | 0035605 | molecular_function | peptidyl-cysteine S-nitrosylase activity |
Q | 0035606 | biological_process | peptidyl-cysteine S-trans-nitrosylation |
Q | 0042802 | molecular_function | identical protein binding |
Q | 0043123 | biological_process | positive regulation of canonical NF-kappaB signal transduction |
Q | 0043231 | cellular_component | intracellular membrane-bounded organelle |
Q | 0045087 | biological_process | innate immune response |
Q | 0048471 | cellular_component | perinuclear region of cytoplasm |
Q | 0050661 | molecular_function | NADP binding |
Q | 0050821 | biological_process | protein stabilization |
Q | 0050832 | biological_process | defense response to fungus |
Q | 0051287 | molecular_function | NAD binding |
Q | 0051402 | biological_process | neuron apoptotic process |
Q | 0051873 | biological_process | killing by host of symbiont cells |
Q | 0061844 | biological_process | antimicrobial humoral immune response mediated by antimicrobial peptide |
Q | 0070062 | cellular_component | extracellular exosome |
Q | 0071346 | biological_process | cellular response to type II interferon |
Q | 0097452 | cellular_component | GAIT complex |
Q | 0097718 | molecular_function | disordered domain specific binding |
Q | 1990904 | cellular_component | ribonucleoprotein complex |
R | 0000226 | biological_process | microtubule cytoskeleton organization |
R | 0001819 | biological_process | positive regulation of cytokine production |
R | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
R | 0005515 | molecular_function | protein binding |
R | 0005634 | cellular_component | nucleus |
R | 0005737 | cellular_component | cytoplasm |
R | 0005811 | cellular_component | lipid droplet |
R | 0005829 | cellular_component | cytosol |
R | 0005856 | cellular_component | cytoskeleton |
R | 0005886 | cellular_component | plasma membrane |
R | 0006006 | biological_process | glucose metabolic process |
R | 0006096 | biological_process | glycolytic process |
R | 0006417 | biological_process | regulation of translation |
R | 0006915 | biological_process | apoptotic process |
R | 0008017 | molecular_function | microtubule binding |
R | 0010951 | biological_process | negative regulation of endopeptidase activity |
R | 0015630 | cellular_component | microtubule cytoskeleton |
R | 0016020 | cellular_component | membrane |
R | 0016241 | biological_process | regulation of macroautophagy |
R | 0016491 | molecular_function | oxidoreductase activity |
R | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
R | 0016740 | molecular_function | transferase activity |
R | 0017148 | biological_process | negative regulation of translation |
R | 0019828 | molecular_function | aspartic-type endopeptidase inhibitor activity |
R | 0031640 | biological_process | killing of cells of another organism |
R | 0031965 | cellular_component | nuclear membrane |
R | 0031982 | cellular_component | vesicle |
R | 0032481 | biological_process | positive regulation of type I interferon production |
R | 0035605 | molecular_function | peptidyl-cysteine S-nitrosylase activity |
R | 0035606 | biological_process | peptidyl-cysteine S-trans-nitrosylation |
R | 0042802 | molecular_function | identical protein binding |
R | 0043123 | biological_process | positive regulation of canonical NF-kappaB signal transduction |
R | 0043231 | cellular_component | intracellular membrane-bounded organelle |
R | 0045087 | biological_process | innate immune response |
R | 0048471 | cellular_component | perinuclear region of cytoplasm |
R | 0050661 | molecular_function | NADP binding |
R | 0050821 | biological_process | protein stabilization |
R | 0050832 | biological_process | defense response to fungus |
R | 0051287 | molecular_function | NAD binding |
R | 0051402 | biological_process | neuron apoptotic process |
R | 0051873 | biological_process | killing by host of symbiont cells |
R | 0061844 | biological_process | antimicrobial humoral immune response mediated by antimicrobial peptide |
R | 0070062 | cellular_component | extracellular exosome |
R | 0071346 | biological_process | cellular response to type II interferon |
R | 0097452 | cellular_component | GAIT complex |
R | 0097718 | molecular_function | disordered domain specific binding |
R | 1990904 | cellular_component | ribonucleoprotein complex |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | binding site for residue EDO O 401 |
Chain | Residue |
O | LYS162 |
O | VAL163 |
O | ASP166 |
O | ASN167 |
O | HOH543 |
O | HOH608 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue EDO O 402 |
Chain | Residue |
O | HOH655 |
O | ASP39 |
O | LEU40 |
O | ASN41 |
site_id | AC3 |
Number of Residues | 4 |
Details | binding site for residue PEG O 403 |
Chain | Residue |
O | PRO129 |
O | MET130 |
O | PHE131 |
O | HOH582 |
site_id | AC4 |
Number of Residues | 3 |
Details | binding site for residue ZN O 404 |
Chain | Residue |
O | HIS57 |
O | HOH559 |
O | HOH783 |
site_id | AC5 |
Number of Residues | 4 |
Details | binding site for residue ZN O 405 |
Chain | Residue |
O | ASP289 |
O | HIS291 |
O | HOH598 |
O | HOH741 |
site_id | AC6 |
Number of Residues | 13 |
Details | binding site for residue F4F O 406 |
Chain | Residue |
O | PRO124 |
O | SER151 |
O | CYS152 |
O | THR153 |
O | HIS179 |
O | THR211 |
O | GLY212 |
O | ARG234 |
O | NAD407 |
O | HOH508 |
O | HOH509 |
O | HOH535 |
O | HOH563 |
site_id | AC7 |
Number of Residues | 33 |
Details | binding site for residue NAD O 407 |
Chain | Residue |
O | ASN9 |
O | GLY10 |
O | PHE11 |
O | GLY12 |
O | ARG13 |
O | ILE14 |
O | ASN34 |
O | ASP35 |
O | PRO36 |
O | PHE37 |
O | ARG80 |
O | SER98 |
O | THR99 |
O | GLY100 |
O | SER122 |
O | ALA123 |
O | CYS152 |
O | ALA183 |
O | ASN316 |
O | TYR320 |
O | F4F406 |
O | HOH530 |
O | HOH538 |
O | HOH558 |
O | HOH569 |
O | HOH591 |
O | HOH595 |
O | HOH597 |
O | HOH599 |
O | HOH616 |
O | HOH657 |
O | HOH664 |
O | HOH674 |
site_id | AC8 |
Number of Residues | 3 |
Details | binding site for residue EDO Q 401 |
Chain | Residue |
Q | PRO129 |
Q | MET130 |
Q | ASN136 |
site_id | AC9 |
Number of Residues | 5 |
Details | binding site for residue EDO Q 402 |
Chain | Residue |
O | HOH770 |
Q | GLY88 |
Q | ASP89 |
Q | GLY115 |
Q | HOH668 |
site_id | AD1 |
Number of Residues | 5 |
Details | binding site for residue EDO Q 403 |
Chain | Residue |
Q | ASP39 |
Q | LEU40 |
Q | ILE76 |
Q | GLN78 |
Q | HOH643 |
site_id | AD2 |
Number of Residues | 6 |
Details | binding site for residue EDO Q 404 |
Chain | Residue |
O | TYR49 |
Q | THR277 |
Q | HIS279 |
Q | HOH588 |
Q | HOH607 |
Q | HOH628 |
site_id | AD3 |
Number of Residues | 4 |
Details | binding site for residue EDO Q 405 |
Chain | Residue |
P | GLU106 |
Q | PRO252 |
Q | LYS254 |
Q | ASP305 |
site_id | AD4 |
Number of Residues | 5 |
Details | binding site for residue ZN Q 406 |
Chain | Residue |
Q | ASP289 |
Q | HIS291 |
Q | HOH588 |
Q | HOH651 |
Q | HOH735 |
site_id | AD5 |
Number of Residues | 30 |
Details | binding site for residue NAD Q 408 |
Chain | Residue |
Q | ARG13 |
Q | ILE14 |
Q | ASN34 |
Q | ASP35 |
Q | PRO36 |
Q | PHE37 |
Q | ARG80 |
Q | SER98 |
Q | THR99 |
Q | GLY100 |
Q | SER122 |
Q | ALA123 |
Q | CYS152 |
Q | ALA183 |
Q | ASN316 |
Q | TYR320 |
Q | F4F407 |
Q | HOH509 |
Q | HOH525 |
Q | HOH558 |
Q | HOH567 |
Q | HOH584 |
Q | HOH659 |
Q | HOH677 |
Q | HOH696 |
Q | HOH702 |
Q | ASN9 |
Q | GLY10 |
Q | PHE11 |
Q | GLY12 |
site_id | AD6 |
Number of Residues | 4 |
Details | binding site for residue EDO P 401 |
Chain | Residue |
P | THR277 |
P | HIS279 |
P | PHE286 |
P | HOH586 |
site_id | AD7 |
Number of Residues | 5 |
Details | binding site for residue EDO P 402 |
Chain | Residue |
P | ARG20 |
P | ASN24 |
P | PHE56 |
P | HIS57 |
P | PHE318 |
site_id | AD8 |
Number of Residues | 3 |
Details | binding site for residue EDO P 403 |
Chain | Residue |
P | LYS254 |
P | ASN304 |
P | ASP305 |
site_id | AD9 |
Number of Residues | 6 |
Details | binding site for residue ZN P 404 |
Chain | Residue |
O | HIS330 |
O | HOH528 |
O | HOH549 |
P | GLU335 |
P | HOH624 |
P | HOH666 |
site_id | AE1 |
Number of Residues | 5 |
Details | binding site for residue ZN P 405 |
Chain | Residue |
P | ASP289 |
P | HIS291 |
P | HOH586 |
P | HOH664 |
P | HOH721 |
site_id | AE2 |
Number of Residues | 5 |
Details | binding site for residue EDO R 401 |
Chain | Residue |
R | GLY300 |
R | ILE301 |
R | ALA302 |
R | HOH502 |
R | HOH605 |
site_id | AE3 |
Number of Residues | 5 |
Details | binding site for residue GOL R 402 |
Chain | Residue |
R | GLY193 |
R | LYS194 |
R | TRP196 |
R | HOH535 |
R | HOH606 |
site_id | AE4 |
Number of Residues | 17 |
Details | binding site for Di-peptide F4F Q 407 and CYS Q 152 |
Chain | Residue |
Q | PRO124 |
Q | SER151 |
Q | THR153 |
Q | THR154 |
Q | ASN155 |
Q | CYS156 |
Q | THR177 |
Q | HIS179 |
Q | THR211 |
Q | GLY212 |
Q | ALA213 |
Q | ARG234 |
Q | TYR314 |
Q | TYR320 |
Q | NAD408 |
Q | HOH530 |
Q | HOH623 |
Functional Information from PROSITE/UniProt
site_id | PS00071 |
Number of Residues | 8 |
Details | GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTNcL |
Chain | Residue | Details |
O | ALA150-LEU157 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:25086035 |
Chain | Residue | Details |
O | CYS152 | |
Q | CYS152 | |
P | CYS152 | |
R | CYS152 |
site_id | SWS_FT_FI2 |
Number of Residues | 20 |
Details | BINDING: BINDING => ECO:0000269|PubMed:16239728, ECO:0000269|PubMed:16510976 |
Chain | Residue | Details |
O | ASN316 | |
Q | ARG13 | |
Q | ASP35 | |
Q | ARG80 | |
Q | SER122 | |
Q | ASN316 | |
P | ARG13 | |
P | ASP35 | |
P | ARG80 | |
P | SER122 | |
P | ASN316 | |
R | ARG13 | |
R | ASP35 | |
R | ARG80 | |
R | SER122 | |
R | ASN316 | |
O | ARG13 | |
O | ASP35 | |
O | ARG80 | |
O | SER122 |
site_id | SWS_FT_FI3 |
Number of Residues | 16 |
Details | BINDING: BINDING => ECO:0000250|UniProtKB:P22513 |
Chain | Residue | Details |
R | SER151 | |
R | THR182 | |
R | THR211 | |
R | ARG234 | |
O | SER151 | |
O | THR182 | |
O | THR211 | |
O | ARG234 | |
Q | SER151 | |
Q | THR182 | |
Q | THR211 | |
Q | ARG234 | |
P | SER151 | |
P | THR182 | |
P | THR211 | |
P | ARG234 |
site_id | SWS_FT_FI4 |
Number of Residues | 4 |
Details | SITE: Activates thiol group during catalysis => ECO:0000305|PubMed:16239728, ECO:0000305|PubMed:16510976 |
Chain | Residue | Details |
O | HIS179 | |
Q | HIS179 | |
P | HIS179 | |
R | HIS179 |
site_id | SWS_FT_FI5 |
Number of Residues | 20 |
Details | MOD_RES: N6,N6-dimethyllysine => ECO:0000269|PubMed:18183946 |
Chain | Residue | Details |
Q | LYS263 | |
Q | LYS334 | |
P | LYS5 | |
P | LYS66 | |
P | LYS260 | |
P | LYS263 | |
P | LYS334 | |
R | LYS5 | |
R | LYS66 | |
R | LYS260 | |
R | LYS263 | |
R | LYS334 | |
O | LYS5 | |
O | LYS66 | |
O | LYS260 | |
O | LYS263 | |
O | LYS334 | |
Q | LYS5 | |
Q | LYS66 | |
Q | LYS260 |
site_id | SWS_FT_FI6 |
Number of Residues | 28 |
Details | MOD_RES: Deamidated asparagine => ECO:0000269|PubMed:18183946 |
Chain | Residue | Details |
O | ASN155 | |
O | ASN225 | |
O | ASN316 | |
Q | ASN9 | |
Q | ASN64 | |
Q | ASN70 | |
Q | ASN149 | |
Q | ASN155 | |
Q | ASN225 | |
Q | ASN316 | |
P | ASN9 | |
P | ASN64 | |
P | ASN70 | |
P | ASN149 | |
P | ASN155 | |
P | ASN225 | |
P | ASN316 | |
R | ASN9 | |
R | ASN64 | |
R | ASN70 | |
R | ASN149 | |
R | ASN155 | |
R | ASN225 | |
R | ASN316 | |
O | ASN9 | |
O | ASN64 | |
O | ASN70 | |
O | ASN149 |
site_id | SWS_FT_FI7 |
Number of Residues | 4 |
Details | MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:15592455 |
Chain | Residue | Details |
O | TYR42 | |
Q | TYR42 | |
P | TYR42 | |
R | TYR42 |
site_id | SWS_FT_FI8 |
Number of Residues | 4 |
Details | MOD_RES: Methionine sulfoxide; in vitro => ECO:0000305|PubMed:25086035 |
Chain | Residue | Details |
O | MET46 | |
Q | MET46 | |
P | MET46 | |
R | MET46 |
site_id | SWS_FT_FI9 |
Number of Residues | 12 |
Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
Chain | Residue | Details |
Q | LYS219 | |
Q | LYS254 | |
P | LYS61 | |
P | LYS219 | |
P | LYS254 | |
R | LYS61 | |
R | LYS219 | |
R | LYS254 | |
O | LYS61 | |
O | LYS219 | |
O | LYS254 | |
Q | LYS61 |
site_id | SWS_FT_FI10 |
Number of Residues | 4 |
Details | MOD_RES: Phosphothreonine => ECO:0000269|PubMed:18183946, ECO:0007744|PubMed:20068231 |
Chain | Residue | Details |
O | THR75 | |
Q | THR75 | |
P | THR75 | |
R | THR75 |
site_id | SWS_FT_FI11 |
Number of Residues | 4 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
Chain | Residue | Details |
O | SER83 | |
Q | SER83 | |
P | SER83 | |
R | SER83 |
site_id | SWS_FT_FI12 |
Number of Residues | 8 |
Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:18183946 |
Chain | Residue | Details |
P | SER122 | |
P | SER148 | |
R | SER122 | |
R | SER148 | |
O | SER148 | |
Q | SER122 | |
Q | SER148 | |
O | SER122 |
site_id | SWS_FT_FI13 |
Number of Residues | 4 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163 |
Chain | Residue | Details |
Q | SER151 | |
P | SER151 | |
R | SER151 | |
O | SER151 |
site_id | SWS_FT_FI14 |
Number of Residues | 4 |
Details | MOD_RES: S-nitrosocysteine; in reversibly inhibited form => ECO:0000250|UniProtKB:P04797 |
Chain | Residue | Details |
O | CYS152 | |
P | CYS152 | |
Q | CYS152 | |
R | CYS152 |
site_id | SWS_FT_FI15 |
Number of Residues | 4 |
Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163 |
Chain | Residue | Details |
O | THR153 | |
Q | THR153 | |
P | THR153 | |
R | THR153 |
site_id | SWS_FT_FI16 |
Number of Residues | 8 |
Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569 |
Chain | Residue | Details |
P | THR177 | |
P | THR182 | |
R | THR177 | |
R | THR182 | |
O | THR177 | |
O | THR182 | |
Q | THR177 | |
Q | THR182 |
site_id | SWS_FT_FI17 |
Number of Residues | 4 |
Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:24275569 |
Chain | Residue | Details |
O | THR184 | |
Q | THR184 | |
P | THR184 | |
R | THR184 |
site_id | SWS_FT_FI18 |
Number of Residues | 8 |
Details | MOD_RES: N6-malonyllysine; alternate => ECO:0000269|PubMed:21908771 |
Chain | Residue | Details |
Q | LYS194 | |
Q | LYS215 | |
P | LYS194 | |
P | LYS215 | |
O | LYS194 | |
O | LYS215 | |
R | LYS194 | |
R | LYS215 |
site_id | SWS_FT_FI19 |
Number of Residues | 4 |
Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:19690332 |
Chain | Residue | Details |
Q | THR211 | |
P | THR211 | |
R | THR211 | |
O | THR211 |
site_id | SWS_FT_FI20 |
Number of Residues | 4 |
Details | MOD_RES: N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861 |
Chain | Residue | Details |
O | LYS227 | |
Q | LYS227 | |
P | LYS227 | |
R | LYS227 |
site_id | SWS_FT_FI21 |
Number of Residues | 4 |
Details | MOD_RES: Phosphothreonine => ECO:0000269|PubMed:18183946, ECO:0007744|PubMed:23186163 |
Chain | Residue | Details |
O | THR229 | |
Q | THR229 | |
P | THR229 | |
R | THR229 |
site_id | SWS_FT_FI22 |
Number of Residues | 4 |
Details | MOD_RES: Phosphothreonine => ECO:0000269|PubMed:18183946 |
Chain | Residue | Details |
O | THR237 | |
Q | THR237 | |
P | THR237 | |
R | THR237 |
site_id | SWS_FT_FI23 |
Number of Residues | 4 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569 |
Chain | Residue | Details |
O | SER241 | |
Q | SER241 | |
P | SER241 | |
R | SER241 |
site_id | SWS_FT_FI24 |
Number of Residues | 4 |
Details | MOD_RES: S-nitrosocysteine => ECO:0000269|PubMed:22771119, ECO:0000269|PubMed:25417112 |
Chain | Residue | Details |
O | CYS247 | |
Q | CYS247 | |
P | CYS247 | |
R | CYS247 |
site_id | SWS_FT_FI25 |
Number of Residues | 4 |
Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:18183946, ECO:0007744|PubMed:19690332 |
Chain | Residue | Details |
O | SER312 | |
Q | SER312 | |
P | SER312 | |
R | SER312 |
site_id | SWS_FT_FI26 |
Number of Residues | 4 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
Chain | Residue | Details |
O | SER333 | |
Q | SER333 | |
P | SER333 | |
R | SER333 |
site_id | SWS_FT_FI27 |
Number of Residues | 8 |
Details | CARBOHYD: (Microbial infection) N-beta-linked (GlcNAc) arginine => ECO:0000269|PubMed:28522607 |
Chain | Residue | Details |
P | ARG197 | |
P | ARG200 | |
R | ARG197 | |
R | ARG200 | |
O | ARG197 | |
O | ARG200 | |
Q | ARG197 | |
Q | ARG200 |
site_id | SWS_FT_FI28 |
Number of Residues | 8 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
Chain | Residue | Details |
P | LYS186 | |
R | LYS186 | |
O | LYS186 | |
Q | LYS186 |