6M3T
Crystal structure of the mouse endonuclease EndoG(H138A/C110A), space group P41212
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 301 |
| Chain | Residue |
| A | GLY137 |
| A | ALA138 |
| A | GLN164 |
| A | ASN169 |
| A | HOH431 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 301 |
| Chain | Residue |
| B | HOH421 |
| B | ARG136 |
| B | GLY137 |
| B | ALA138 |
| B | ASN169 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10047, ECO:0000269|PubMed:32095813, ECO:0000269|PubMed:32192768 |
| Chain | Residue | Details |
| B | ALA138 | |
| A | ALA138 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:32095813, ECO:0000269|PubMed:32192768, ECO:0007744|PDB:6LYF, ECO:0007744|PDB:6NJT |
| Chain | Residue | Details |
| B | ASN169 | |
| A | ASN169 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Essential for catalytic activity => ECO:0000269|PubMed:32192768 |
| Chain | Residue | Details |
| B | ARG107 | |
| A | ARG107 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q14249 |
| Chain | Residue | Details |
| B | THR125 | |
| A | THR125 |
