Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6M0P

Hydroxylamine oxidoreductase in complex with juglone

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	binding site for residue HEC A 601

Chain	Residue
A	TYR140
A	HIS267
A	SER277
A	ARG278
A	ARG319
A	LEU320
A	ALA335
A	MET339
A	HIS347
A	HEC602
A	HEC606
A	LYS141
A	CYS196
A	HIS200
A	GLU203
A	HIS228
A	ASN259
A	CYS263
A	CYS266

site_id	AC2
Number of Residues	16
Details	binding site for residue HEC A 602

Chain	Residue
A	THR122
A	HIS123
A	LYS141
A	LYS144
A	LEU145
A	VAL167
A	THR195
A	CYS196
A	CYS199
A	HIS200
A	CYS263
A	HIS267
A	PHE272
A	ALA274
A	HEC601
A	HEC604

site_id	AC3
Number of Residues	19
Details	binding site for residue HEC A 603

Chain	Residue
A	TYR81
A	TYR88
A	SER93
A	ALA98
A	GLU99
A	ASP102
A	CYS103
A	CYS106
A	HIS107
A	GLU110
A	CYS169
A	HIS173
A	HIS184
A	ILE188
A	MET190
A	HEC604
C	SER389
C	GLU390
C	ARG391

site_id	AC4
Number of Residues	23
Details	binding site for residue HEC A 604

Chain	Residue
A	TYR81
A	PRO84
A	HIS107
A	TRP114
A	TRP118
A	HIS123
A	VAL167
A	GLY168
A	CYS169
A	CYS172
A	HIS173
A	MET190
A	PRO191
A	LYS262
A	ASP264
A	ARG269
A	HIS270
A	PHE272
A	HEC602
A	HEC603
C	HIS388
C	SER389
C	PHE392

site_id	AC5
Number of Residues	21
Details	binding site for residue HEC A 605

Chain	Residue
A	HIS287
A	ASN294
A	TYR298
A	HIS303
A	PRO332
A	THR333
A	CYS334
A	CYS337
A	HIS338
A	THR353
A	ARG354
A	TRP355
A	ALA356
A	TRP380
A	MET400
A	ALA482
A	HIS483
A	HEC606
A	HEC607
A	HOH705
A	ISW611

site_id	AC6
Number of Residues	20
Details	binding site for residue HEC A 606

Chain	Residue
A	SER227
A	HIS228
A	ASP231
A	ALA234
A	CYS256
A	HIS257
A	ASN259
A	ASN265
A	ALA282
A	CYS283
A	CYS286
A	HIS287
A	CYS334
A	ILE349
A	THR353
A	ALA356
A	HEC601
A	HEC605
A	ISW611
A	PRO226

site_id	AC7
Number of Residues	23
Details	binding site for residue HEC A 607

Chain	Residue
A	HIS303
A	LEU306
A	PHE324
A	ASN330
A	ALA331
A	PRO332
A	THR383
A	CYS384
A	CYS387
A	HIS388
A	PHE392
A	TYR396
A	VAL484
A	HEC605
E	MET82
E	TRP114
E	MET255
E	LYS262
E	ASP264
E	ASN265
E	THR268
E	ARG269
E	HOH705

site_id	AC8
Number of Residues	5
Details	binding site for residue PEG A 609

Chain	Residue
A	PHE360
A	TYR411
A	ASN415
A	GLY446
A	LEU467

site_id	AC9
Number of Residues	4
Details	binding site for residue PEG A 610

Chain	Residue
A	TYR358
A	PHE360
A	GLU471
A	ISW611

site_id	AD1
Number of Residues	3
Details	binding site for residue JUG C 608

Chain	Residue
C	TRP221
C	GLU471
C	ISW611

site_id	AD2
Number of Residues	5
Details	binding site for residue 1PE C 609

Chain	Residue
C	PHE360
C	TYR411
C	ASN415
C	GLY446
C	LEU467

site_id	AD3
Number of Residues	3
Details	binding site for residue 1PE C 610

Chain	Residue
C	GLU366
C	GLN412
D	PRO32

site_id	AD4
Number of Residues	7
Details	binding site for residue JUG E 608

Chain	Residue
A	ISW608
A	HOH730
E	THR238
E	TYR358
E	PHE448
E	GLU471
E	PEG609

site_id	AD5
Number of Residues	4
Details	binding site for residue PEG E 609

Chain	Residue
E	TYR411
E	PHE445
E	GLY446
E	JUG608

site_id	AD6
Number of Residues	55
Details	binding site for Di-peptide ISW A 608 and CYS E 256

Chain	Residue
A	CYS253
A	THR254
A	MET255
A	HIS257
A	THR258
A	PRO486
A	THR490
A	TYR491
A	HEC606
A	HOH730
C	TRP114
C	MET255
C	LYS262
C	ASP264
C	THR268
C	ARG269
C	PRO486
A	ISW611
E	TRP221
E	ARG225
E	ALA234
E	ASN235
E	THR238
E	TRP241
E	CYS253
E	THR254
E	MET255
E	HIS257
E	THR258
E	THR285
E	CYS286
E	HIS287
E	HIS292
E	ASN294
E	HIS303
E	LEU306
E	PHE324
E	ASN330
E	ALA331
E	PRO332
E	ASN357
E	TYR358
E	THR383
E	CYS384
E	CYS387
E	HIS388
E	PHE392
E	TYR396
E	PHE452
E	VAL484
E	HEC605
E	HEC606
E	JUG608
E	HOH703
E	HOH712

site_id	AD7
Number of Residues	57
Details	binding site for Di-peptide ISW A 608 and CYS E 253

Chain	Residue
A	ASN235
A	ALA250
A	GLU251
A	GLY252
A	THR254
A	MET255
A	CYS256
A	HIS257
A	THR490
A	TYR491
A	HOH730
C	TRP114
C	MET255
C	LYS262
C	ASP264
C	THR268
C	ARG269
A	ISW611
E	TRP221
E	ARG225
E	ALA234
E	ASN235
E	THR238
E	TRP241
E	ALA250
E	GLU251
E	GLY252
E	THR254
E	MET255
E	CYS256
E	HIS257
E	THR285
E	CYS286
E	HIS287
E	HIS292
E	ASN294
E	HIS303
E	LEU306
E	PHE324
E	ASN330
E	ALA331
E	PRO332
E	ASN357
E	TYR358
E	THR383
E	CYS384
E	CYS387
E	HIS388
E	PHE392
E	TYR396
E	PHE452
E	VAL484
E	HEC605
E	HEC606
E	JUG608
E	HOH703
E	HOH712

site_id	AD8
Number of Residues	29
Details	binding site for Di-peptide ISW C 601 and TYR C 491

Chain	Residue
A	TRP221
A	ARG225
A	ALA234
A	ASN235
A	THR238
A	TRP241
A	CYS253
A	CYS256
A	HIS257
A	THR285
A	CYS286
A	HIS287
A	ASP291
A	HIS292
A	ASN294
A	ASN357
A	TYR358
A	PHE448
A	PHE452
A	HEC605
A	HEC606
A	PEG610
A	HOH703
A	HOH708
A	HOH720
A	HOH727
C	THR490
C	THR492
C	GLY496

site_id	AD9
Number of Residues	29
Details	binding site for Di-peptide ISW C 601 and TYR C 491

Chain	Residue
A	TRP221
A	ARG225
A	ALA234
A	ASN235
A	THR238
A	TRP241
A	CYS253
A	CYS256
A	HIS257
A	THR285
A	CYS286
A	HIS287
A	ASP291
A	HIS292
A	ASN294
A	ASN357
A	TYR358
A	PHE448
A	PHE452
A	HEC605
A	HEC606
A	PEG610
A	HOH703
A	HOH708
A	HOH720
A	HOH727
C	THR490
C	THR492
C	GLY496

site_id	AE1
Number of Residues	25
Details	binding site for Di-peptide HEC C 602 and CYS C 263

Chain	Residue
C	TYR140
C	LYS141
C	LYS144
C	ALA193
C	CYS196
C	HIS200
C	GLU203
C	PHE204
C	HIS228
C	ASN259
C	LYS262
C	ASP264
C	ASN265
C	CYS266
C	HIS267
C	SER277
C	ARG278
C	ARG319
C	LEU320
C	ALA335
C	MET339
C	HIS347
C	HEC602
C	HEC606
C	HOH706

site_id	AE2
Number of Residues	26
Details	binding site for Di-peptide HEC C 602 and CYS C 266

Chain	Residue
C	TYR140
C	LYS141
C	LYS144
C	CYS196
C	HIS200
C	GLU203
C	PHE204
C	HIS228
C	ASN259
C	CYS263
C	ASP264
C	ASN265
C	HIS267
C	THR268
C	GLU276
C	SER277
C	ARG278
C	ARG319
C	LEU320
C	ALA335
C	MET339
C	HIS347
C	HEC602
C	HEC606
C	HOH706
C	HOH719

site_id	AE3
Number of Residues	20
Details	binding site for Di-peptide HEC C 603 and CYS C 196

Chain	Residue
C	THR122
C	HIS123
C	LYS141
C	LYS144
C	LEU145
C	VAL148
C	VAL167
C	THR192
C	ALA193
C	ASP194
C	THR195
C	GLY197
C	THR198
C	CYS199
C	HIS200
C	CYS263
C	PHE272
C	ALA274
C	GLU317
C	HEC601

site_id	AE4
Number of Residues	20
Details	binding site for Di-peptide HEC C 603 and CYS C 199

Chain	Residue
C	THR122
C	HIS123
C	LYS141
C	LYS144
C	LEU145
C	VAL148
C	ASN151
C	LEU152
C	VAL167
C	THR195
C	CYS196
C	GLY197
C	THR198
C	HIS200
C	LEU201
C	CYS263
C	PHE272
C	ALA274
C	GLU317
C	HEC601

site_id	AE5
Number of Residues	25
Details	binding site for Di-peptide HEC C 604 and CYS C 103

Chain	Residue
A	LYS161
C	TYR81
C	TYR88
C	PRO91
C	SER93
C	PRO94
C	GLU96
C	ALA98
C	GLU99
C	ARG100
C	LYS101
C	ASP102
C	VAL104
C	GLU105
C	CYS106
C	HIS107
C	GLU110
C	CYS169
C	HIS173
C	HIS184
C	ILE188
C	MET190
C	HEC604
E	SER389
E	ARG391

site_id	AE6
Number of Residues	25
Details	binding site for Di-peptide HEC C 604 and CYS C 106

Chain	Residue
A	LYS161
C	TYR81
C	TYR88
C	PRO91
C	SER93
C	PRO94
C	GLU96
C	ALA98
C	GLU99
C	ASP102
C	CYS103
C	VAL104
C	GLU105
C	HIS107
C	SER108
C	ASP109
C	GLU110
C	CYS169
C	HIS173
C	HIS184
C	ILE188
C	MET190
C	HEC604
E	SER389
E	ARG391

site_id	AE7
Number of Residues	25
Details	binding site for Di-peptide HEC C 605 and CYS C 172

Chain	Residue
C	TYR81
C	PRO84
C	HIS107
C	THR111
C	TRP114
C	VAL115
C	TRP118
C	HIS123
C	VAL167
C	GLY168
C	CYS169
C	ILE170
C	ASP171
C	HIS173
C	VAL174
C	PRO191
C	THR195
C	LYS262
C	ARG269
C	HIS270
C	PHE272
C	HEC603
E	HIS388
E	SER389
E	PHE392

site_id	AE8
Number of Residues	24
Details	binding site for Di-peptide HEC C 605 and CYS C 169

Chain	Residue
C	TYR81
C	PRO84
C	HIS107
C	THR111
C	TRP114
C	VAL115
C	TRP118
C	HIS123
C	VAL167
C	GLY168
C	ILE170
C	ASP171
C	CYS172
C	HIS173
C	PRO191
C	LYS262
C	ARG269
C	HIS270
C	PHE272
C	HEC603
C	HOH714
E	HIS388
E	SER389
E	PHE392

site_id	AE9
Number of Residues	24
Details	binding site for Di-peptide HEC C 606 and CYS C 337

Chain	Residue
C	CYS283
C	HIS287
C	ASN294
C	TYR298
C	HIS303
C	PRO332
C	THR333
C	CYS334
C	ALA335
C	ALA336
C	HIS338
C	LYS352
C	THR353
C	ARG354
C	TRP355
C	ALA356
C	TRP380
C	ALA482
C	HIS483
C	HEC606
C	HEC607
C	HOH705
C	HOH708
C	ISW611

site_id	AF1
Number of Residues	25
Details	binding site for Di-peptide HEC C 606 and CYS C 334

Chain	Residue
C	PRO280
C	CYS283
C	HIS287
C	ASN294
C	TYR298
C	HIS303
C	PRO332
C	THR333
C	ALA335
C	ALA336
C	CYS337
C	HIS338
C	THR353
C	ARG354
C	TRP355
C	ALA356
C	TRP380
C	ALA482
C	HIS483
C	HEC606
C	HEC607
C	HOH705
C	HOH708
C	HOH716
C	ISW611

site_id	AF2
Number of Residues	23
Details	binding site for Di-peptide HEC C 607 and CYS C 286

Chain	Residue
C	PRO226
C	SER227
C	HIS228
C	ASP231
C	CYS256
C	HIS257
C	ASN259
C	ASN265
C	ALA282
C	CYS283
C	ALA284
C	THR285
C	HIS287
C	SER288
C	HIS292
C	CYS334
C	ILE349
C	THR353
C	ALA356
C	HEC601
C	HEC605
C	HOH702
C	ISW611

site_id	AF3
Number of Residues	23
Details	binding site for Di-peptide HEC C 607 and CYS C 283

Chain	Residue
C	PRO226
C	SER227
C	HIS228
C	ASP231
C	CYS256
C	HIS257
C	ASN259
C	ASN265
C	PRO280
C	GLU281
C	ALA282
C	ALA284
C	THR285
C	CYS286
C	HIS287
C	CYS334
C	ILE349
C	THR353
C	ALA356
C	HEC601
C	HEC605
C	HOH702
C	ISW611

site_id	AF4
Number of Residues	24
Details	binding site for Di-peptide HEC C 608 and CYS C 387

Chain	Residue
A	THR111
A	VAL113
A	TRP114
A	MET255
A	LYS262
A	ASP264
A	THR268
A	ARG269
C	HIS303
C	LEU306
C	PHE324
C	ASN330
C	ALA331
C	PRO332
C	TRP380
C	THR383
C	CYS384
C	THR385
C	GLN386
C	HIS388
C	PHE392
C	TYR396
C	VAL484
C	HEC605

site_id	AF5
Number of Residues	24
Details	binding site for Di-peptide HEC C 608 and CYS C 384

Chain	Residue
A	TRP114
A	MET255
A	LYS262
A	ASP264
A	THR268
A	ARG269
C	HIS303
C	LEU306
C	PHE324
C	ASN330
C	ALA331
C	PRO332
C	TRP380
C	VAL381
C	LEU382
C	THR383
C	THR385
C	GLN386
C	CYS387
C	HIS388
C	PHE392
C	TYR396
C	VAL484
C	HEC605

site_id	AF6
Number of Residues	62
Details	binding site for Di-peptide ISW E 601 and CYS C 256

Chain	Residue
A	TRP221
A	ARG225
A	ALA234
A	ASN235
A	THR238
A	TRP241
A	CYS253
A	CYS256
A	HIS257
A	THR285
A	CYS286
A	HIS287
A	HIS292
A	ASN294
A	ASN357
A	TYR358
A	PHE452
A	PRO486
A	HEC605
A	HEC606
A	ISW608
A	PEG610
A	HOH703
A	HOH708
A	HOH720
C	TRP221
C	ARG225
C	ALA234
C	ASN235
C	THR238
C	TRP241
C	CYS253
C	THR254
C	MET255
C	HIS257
C	THR258
C	THR285
C	CYS286
C	HIS287
C	HIS292
C	ASN294
C	ASN357
C	TYR358
C	PHE452
C	THR490
C	TYR491
C	HEC605
C	HEC606
C	JUG608
C	HOH701
C	HOH712
E	CYS253
E	THR254
E	MET255
E	HIS257
E	THR258
E	CYS286
E	PRO486
E	THR490
E	TYR491
E	HEC606
C	HOH724

site_id	AF7
Number of Residues	29
Details	binding site for Di-peptide ISW E 601 and TYR E 491

Chain	Residue
C	TRP221
C	ARG225
C	ALA234
C	ASN235
C	THR238
C	TRP241
C	CYS253
C	CYS256
C	HIS257
C	THR285
C	CYS286
C	HIS287
C	ASP291
C	HIS292
C	ASN294
C	ASN357
C	TYR358
C	PHE448
C	PHE452
C	HEC605
C	HEC606
C	JUG608
C	HOH701
C	HOH711
C	HOH712
E	THR490
E	THR492
E	GLY496
C	HOH724

site_id	AF8
Number of Residues	29
Details	binding site for Di-peptide ISW E 601 and TYR E 491

Chain	Residue
C	TRP221
C	ARG225
C	ALA234
C	ASN235
C	THR238
C	TRP241
C	CYS253
C	CYS256
C	HIS257
C	THR285
C	CYS286
C	HIS287
C	ASP291
C	HIS292
C	ASN294
C	ASN357
C	TYR358
C	PHE448
C	PHE452
C	HEC605
C	HEC606
C	JUG608
C	HOH701
C	HOH711
C	HOH712
E	THR490
E	THR492
E	GLY496
C	HOH724

site_id	AF9
Number of Residues	63
Details	binding site for Di-peptide ISW E 601 and CYS C 253

Chain	Residue
A	TRP221
A	ARG225
A	ALA234
A	ASN235
A	THR238
A	TRP241
A	CYS253
A	CYS256
A	HIS257
A	THR285
A	CYS286
A	HIS287
A	HIS292
A	ASN294
A	ASN357
A	TYR358
A	PHE452
A	HEC605
A	HEC606
A	ISW608
A	PEG610
A	HOH703
A	HOH708
A	HOH720
C	TRP221
C	ARG225
C	ALA234
C	ASN235
C	THR238
C	TRP241
C	ALA250
C	GLU251
C	GLY252
C	THR254
C	MET255
C	CYS256
C	HIS257
C	THR285
C	CYS286
C	HIS287
C	HIS292
C	ASN294
C	ASN357
C	TYR358
C	PHE452
C	THR490
C	TYR491
C	HEC605
C	HEC606
C	JUG608
C	HOH701
C	HOH712
E	ASN235
E	ALA250
E	GLU251
E	GLY252
E	THR254
E	MET255
E	CYS256
E	HIS257
E	THR490
E	TYR491
C	HOH724

site_id	AG1
Number of Residues	22
Details	binding site for Di-peptide HEC E 602 and CYS E 263

Chain	Residue
E	TYR140
E	LYS141
E	ALA193
E	CYS196
E	HIS200
E	GLU203
E	HIS228
E	ASN259
E	LYS262
E	ASP264
E	ASN265
E	CYS266
E	HIS267
E	SER277
E	ARG278
E	ARG319
E	LEU320
E	ALA335
E	MET339
E	HIS347
E	HEC602
E	HEC606

site_id	AG2
Number of Residues	23
Details	binding site for Di-peptide HEC E 602 and CYS E 266

Chain	Residue
E	TYR140
E	LYS141
E	CYS196
E	HIS200
E	GLU203
E	HIS228
E	ASN259
E	CYS263
E	ASP264
E	ASN265
E	HIS267
E	THR268
E	GLU276
E	SER277
E	ARG278
E	ALA282
E	ARG319
E	LEU320
E	ALA335
E	MET339
E	HIS347
E	HEC602
E	HEC606

site_id	AG3
Number of Residues	20
Details	binding site for Di-peptide HEC E 603 and CYS E 199

Chain	Residue
E	THR122
E	HIS123
E	LYS141
E	LEU145
E	VAL148
E	ASN151
E	LEU152
E	VAL167
E	THR195
E	CYS196
E	GLY197
E	THR198
E	HIS200
E	LEU201
E	CYS263
E	HIS267
E	PHE272
E	ALA274
E	HEC601
E	HEC604

site_id	AG4
Number of Residues	19
Details	binding site for Di-peptide HEC E 603 and CYS E 196

Chain	Residue
E	THR122
E	HIS123
E	LYS141
E	LEU145
E	VAL167
E	THR192
E	ALA193
E	ASP194
E	THR195
E	GLY197
E	THR198
E	CYS199
E	HIS200
E	CYS263
E	HIS267
E	PHE272
E	ALA274
E	HEC601
E	HEC604

site_id	AG5
Number of Residues	22
Details	binding site for Di-peptide HEC E 604 and CYS E 106

Chain	Residue
A	SER389
A	GLU390
A	ARG391
E	TYR81
E	TYR88
E	SER93
E	PRO94
E	GLU96
E	ALA98
E	ASP102
E	CYS103
E	VAL104
E	GLU105
E	HIS107
E	SER108
E	ASP109
E	GLU110
E	CYS169
E	HIS173
E	HIS184
E	MET190
E	HEC604

site_id	AG6
Number of Residues	23
Details	binding site for Di-peptide HEC E 604 and CYS E 103

Chain	Residue
A	SER389
A	GLU390
A	ARG391
E	TYR81
E	TYR88
E	SER93
E	PRO94
E	GLU96
E	ALA98
E	GLU99
E	ARG100
E	LYS101
E	ASP102
E	VAL104
E	GLU105
E	CYS106
E	HIS107
E	GLU110
E	CYS169
E	HIS173
E	HIS184
E	MET190
E	HEC604

site_id	AG7
Number of Residues	27
Details	binding site for Di-peptide HEC E 605 and CYS E 172

Chain	Residue
E	ILE170
E	ASP171
E	HIS173
E	VAL174
E	ARG189
E	MET190
E	PRO191
E	THR195
E	LYS262
E	ASP264
E	ARG269
E	HIS270
E	PHE272
E	HEC602
E	HEC603
A	HIS388
A	SER389
A	PHE392
E	TYR81
E	PRO84
E	HIS107
E	TRP114
E	TRP118
E	HIS123
E	VAL167
E	GLY168
E	CYS169

site_id	AG8
Number of Residues	25
Details	binding site for Di-peptide HEC E 605 and CYS E 169

Chain	Residue
A	HIS388
A	SER389
A	PHE392
E	TYR81
E	PRO84
E	CYS103
E	HIS107
E	TRP114
E	TRP118
E	HIS123
E	VAL167
E	GLY168
E	ILE170
E	ASP171
E	CYS172
E	HIS173
E	MET190
E	PRO191
E	LYS262
E	ASP264
E	ARG269
E	HIS270
E	PHE272
E	HEC602
E	HEC603

site_id	AG9
Number of Residues	21
Details	binding site for Di-peptide HEC E 606 and CYS E 337

Chain	Residue
A	ISW608
E	HIS287
E	ASN294
E	TYR298
E	HIS303
E	PRO332
E	THR333
E	CYS334
E	ALA335
E	ALA336
E	HIS338
E	LYS352
E	THR353
E	ARG354
E	TRP355
E	TRP380
E	ALA482
E	HIS483
E	HEC606
E	HEC607
E	HOH711

site_id	AH1
Number of Residues	22
Details	binding site for Di-peptide HEC E 606 and CYS E 334

Chain	Residue
A	ISW608
E	PRO280
E	CYS283
E	HIS287
E	ASN294
E	TYR298
E	HIS303
E	PRO332
E	THR333
E	ALA335
E	ALA336
E	CYS337
E	HIS338
E	THR353
E	ARG354
E	TRP355
E	TRP380
E	ALA482
E	HIS483
E	HEC606
E	HEC607
E	HOH711

site_id	AH2
Number of Residues	24
Details	binding site for Di-peptide HEC E 607 and CYS E 286

Chain	Residue
A	ISW608
E	PRO226
E	SER227
E	HIS228
E	ASP231
E	ALA234
E	CYS256
E	HIS257
E	ASN259
E	ASN265
E	ALA282
E	CYS283
E	ALA284
E	THR285
E	HIS287
E	SER288
E	HIS292
E	CYS334
E	HIS338
E	ILE349
E	THR353
E	ALA356
E	HEC601
E	HEC605

site_id	AH3
Number of Residues	24
Details	binding site for Di-peptide HEC E 607 and CYS E 283

Chain	Residue
A	ISW608
E	PRO226
E	SER227
E	HIS228
E	ASP231
E	ALA234
E	CYS256
E	HIS257
E	ASN259
E	ASN265
E	PRO280
E	GLU281
E	ALA282
E	ALA284
E	THR285
E	CYS286
E	HIS287
E	CYS334
E	HIS338
E	ILE349
E	THR353
E	ALA356
E	HEC601
E	HEC605

site_id	AH4
Number of Residues	23
Details	binding site for Di-peptide HEC E 608 and CYS E 387

Chain	Residue
C	THR111
C	VAL113
C	TRP114
C	MET255
C	LYS262
C	ASP264
C	THR268
C	ARG269
E	HIS303
E	LEU306
E	PHE324
E	ASN330
E	ALA331
E	PRO332
E	THR383
E	CYS384
E	THR385
E	GLN386
E	HIS388
E	PHE392
E	TYR396
E	VAL484
E	HEC605

site_id	AH5
Number of Residues	25
Details	binding site for Di-peptide HEC E 608 and CYS E 384

Chain	Residue
C	TRP114
C	MET255
C	LYS262
C	ASP264
C	THR268
C	ARG269
E	HIS303
E	LEU306
E	PHE324
E	ASN330
E	ALA331
E	PRO332
E	TRP380
E	VAL381
E	LEU382
E	THR383
E	THR385
E	GLN386
E	CYS387
E	HIS388
E	PHE392
E	ALA393
E	TYR396
E	VAL484
E	HEC605

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	48
Details	BINDING: covalent => ECO:0000269\|PubMed:24302732, ECO:0000269\|PubMed:9095195, ECO:0007744\|PDB:1FGJ, ECO:0007744\|PDB:4N4N, ECO:0007744\|PDB:4N4O

Chain	Residue	Details
A	CYS103
A	CYS266
A	CYS283
A	CYS286
A	CYS334
A	CYS337
A	CYS384
A	CYS387
C	CYS103
C	CYS106
C	CYS169
A	CYS106
C	CYS172
C	CYS196
C	CYS199
C	CYS253
C	CYS256
C	CYS263
C	CYS266
C	CYS283
C	CYS286
C	CYS334
A	CYS169
C	CYS337
C	CYS384
C	CYS387
E	CYS103
E	CYS106
E	CYS169
E	CYS172
E	CYS196
E	CYS199
E	CYS253
A	CYS172
E	CYS256
E	CYS263
E	CYS266
E	CYS283
E	CYS286
E	CYS334
E	CYS337
E	CYS384
E	CYS387
A	CYS196
A	CYS199
A	CYS253
A	CYS256
A	CYS263

site_id	SWS_FT_FI2
Number of Residues	45
Details	BINDING: axial binding residue => ECO:0000269\|PubMed:24302732, ECO:0000269\|PubMed:9095195, ECO:0007744\|PDB:1FGJ, ECO:0007744\|PDB:4N4N, ECO:0007744\|PDB:4N4O

Chain	Residue	Details
A	HIS107
A	HIS287
A	HIS303
A	HIS338
A	HIS347
A	HIS388
A	HIS483
C	HIS107
C	HIS123
C	HIS173
C	HIS184
A	HIS123
C	HIS200
C	HIS228
C	HIS257
C	HIS267
C	HIS270
C	HIS287
C	HIS303
C	HIS338
C	HIS347
C	HIS388
A	HIS173
C	HIS483
E	HIS107
E	HIS123
E	HIS173
E	HIS184
E	HIS200
E	HIS228
E	HIS257
E	HIS267
E	HIS270
A	HIS184
E	HIS287
E	HIS303
E	HIS338
E	HIS347
E	HIS388
E	HIS483
A	HIS200
A	HIS228
A	HIS257
A	HIS267
A	HIS270

site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269\|PubMed:24302732, ECO:0007744\|PDB:4N4O

Chain	Residue	Details
A	HIS292
C	HIS292
E	HIS292

site_id	SWS_FT_FI4
Number of Residues	3
Details	BINDING: covalent; ligand shared between tetrameric partners => ECO:0000269\|PubMed:24302732

Chain	Residue	Details
A	TYR491
C	TYR491
E	TYR491

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	5
Details	M-CSA 581

Chain	Residue	Details
A	HIS257	electrostatic stabiliser
A	ASP291	steric role
A	HIS292	steric role
A	TYR358	steric role
A	TYR491	activator, covalently attached

site_id	MCSA2
Number of Residues	5
Details	M-CSA 581

Chain	Residue	Details
C	HIS257	electrostatic stabiliser
C	ASP291	steric role
C	HIS292	steric role
C	TYR358	steric role
C	TYR491	activator, covalently attached

site_id	MCSA3
Number of Residues	5
Details	M-CSA 581

Chain	Residue	Details
E	HIS257	electrostatic stabiliser
E	ASP291	steric role
E	HIS292	steric role
E	TYR358	steric role
E	TYR491	activator, covalently attached

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)