6LZ1

Structure of S.pombe alpha-mannosidase Ams1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000328	cellular_component	fungal-type vacuole lumen
A	0000329	cellular_component	fungal-type vacuole membrane
A	0003824	molecular_function	catalytic activity
A	0004559	molecular_function	alpha-mannosidase activity
A	0004571	molecular_function	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005773	cellular_component	vacuole
A	0005829	cellular_component	cytosol
A	0005975	biological_process	carbohydrate metabolic process
A	0006013	biological_process	mannose metabolic process
A	0009313	biological_process	oligosaccharide catabolic process
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0030246	molecular_function	carbohydrate binding
A	0046872	molecular_function	metal ion binding
A	0052767	molecular_function	mannosyl-oligosaccharide 1,6-alpha-mannosidase activity
A	0052768	molecular_function	mannosyl-oligosaccharide 1,3-alpha-mannosidase activity
B	0000328	cellular_component	fungal-type vacuole lumen
B	0000329	cellular_component	fungal-type vacuole membrane
B	0003824	molecular_function	catalytic activity
B	0004559	molecular_function	alpha-mannosidase activity
B	0004571	molecular_function	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005773	cellular_component	vacuole
B	0005829	cellular_component	cytosol
B	0005975	biological_process	carbohydrate metabolic process
B	0006013	biological_process	mannose metabolic process
B	0009313	biological_process	oligosaccharide catabolic process
B	0016787	molecular_function	hydrolase activity
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0030246	molecular_function	carbohydrate binding
B	0046872	molecular_function	metal ion binding
B	0052767	molecular_function	mannosyl-oligosaccharide 1,6-alpha-mannosidase activity
B	0052768	molecular_function	mannosyl-oligosaccharide 1,3-alpha-mannosidase activity
C	0000328	cellular_component	fungal-type vacuole lumen
C	0000329	cellular_component	fungal-type vacuole membrane
C	0003824	molecular_function	catalytic activity
C	0004559	molecular_function	alpha-mannosidase activity
C	0004571	molecular_function	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005773	cellular_component	vacuole
C	0005829	cellular_component	cytosol
C	0005975	biological_process	carbohydrate metabolic process
C	0006013	biological_process	mannose metabolic process
C	0009313	biological_process	oligosaccharide catabolic process
C	0016787	molecular_function	hydrolase activity
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0030246	molecular_function	carbohydrate binding
C	0046872	molecular_function	metal ion binding
C	0052767	molecular_function	mannosyl-oligosaccharide 1,6-alpha-mannosidase activity
C	0052768	molecular_function	mannosyl-oligosaccharide 1,3-alpha-mannosidase activity
D	0000328	cellular_component	fungal-type vacuole lumen
D	0000329	cellular_component	fungal-type vacuole membrane
D	0003824	molecular_function	catalytic activity
D	0004559	molecular_function	alpha-mannosidase activity
D	0004571	molecular_function	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0005773	cellular_component	vacuole
D	0005829	cellular_component	cytosol
D	0005975	biological_process	carbohydrate metabolic process
D	0006013	biological_process	mannose metabolic process
D	0009313	biological_process	oligosaccharide catabolic process
D	0016787	molecular_function	hydrolase activity
D	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
D	0030246	molecular_function	carbohydrate binding
D	0046872	molecular_function	metal ion binding
D	0052767	molecular_function	mannosyl-oligosaccharide 1,6-alpha-mannosidase activity
D	0052768	molecular_function	mannosyl-oligosaccharide 1,3-alpha-mannosidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue ZN A 1201

Chain	Residue
A	HIS290
A	ASP292
A	ASP402
A	HIS615
A	ASP616

---

site_id	AC2
Number of Residues	5
Details	binding site for residue ZN B 1201

Chain	Residue
B	ASP616
B	HIS290
B	ASP292
B	ASP402
B	HIS615

---

site_id	AC3
Number of Residues	5
Details	binding site for residue ZN C 1201

Chain	Residue
C	HIS290
C	ASP292
C	ASP402
C	HIS615
C	ASP616

---

site_id	AC4
Number of Residues	5
Details	binding site for residue ZN D 1201

Chain	Residue
D	HIS290
D	ASP292
D	ASP402
D	HIS615
D	ASP616

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Nucleophile","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---