6LVF
Cryo-EM structure of the multiple peptide resistance factor (MprF) loaded with one lysyl-phosphatidylglycerol molecule
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016755 | molecular_function | aminoacyltransferase activity |
| A | 0050071 | molecular_function | phosphatidylglycerol lysyltransferase activity |
| A | 0055091 | biological_process | phospholipid homeostasis |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0016755 | molecular_function | aminoacyltransferase activity |
| B | 0050071 | molecular_function | phosphatidylglycerol lysyltransferase activity |
| B | 0055091 | biological_process | phospholipid homeostasis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue EV9 B 1001 |
| Chain | Residue |
| B | LEU23 |
| B | TYR307 |
| B | ASN117 |
| B | THR152 |
| B | GLY156 |
| B | ASP234 |
| B | ILE262 |
| B | GLY265 |
| B | HIS271 |
| B | ALA274 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue LHG B 1002 |
| Chain | Residue |
| A | LHG1002 |
| A | PGT1003 |
| B | PHE150 |
| B | SER161 |
| B | MET165 |
| B | ARG204 |
| B | ASN205 |
| B | SER221 |
| B | TRP224 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue PGT B 1003 |
| Chain | Residue |
| B | LEU73 |
| B | PHE77 |
| B | PHE233 |
| B | SER240 |
| B | TYR243 |
| B | VAL244 |
| B | LEU246 |
| B | GLU248 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue EV9 A 1001 |
| Chain | Residue |
| A | LEU23 |
| A | ASN117 |
| A | THR152 |
| A | GLY156 |
| A | ASP234 |
| A | ILE262 |
| A | GLY265 |
| A | HIS271 |
| A | ALA274 |
| A | TYR307 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue LHG A 1002 |
| Chain | Residue |
| A | PHE150 |
| A | SER161 |
| A | MET165 |
| A | ARG204 |
| A | ASN205 |
| A | SER221 |
| A | TRP224 |
| B | LEU229 |
| B | LHG1002 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue PGT A 1003 |
| Chain | Residue |
| A | LEU73 |
| A | PHE77 |
| A | PHE233 |
| A | SER240 |
| A | TYR243 |
| A | VAL244 |
| A | LEU246 |
| A | GLU248 |
| B | LHG1002 |
