Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0016829 | molecular_function | lyase activity |
| A | 0046306 | biological_process | alkanesulfonate catabolic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0016829 | molecular_function | lyase activity |
| B | 0046306 | biological_process | alkanesulfonate catabolic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0016829 | molecular_function | lyase activity |
| C | 0046306 | biological_process | alkanesulfonate catabolic process |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0016829 | molecular_function | lyase activity |
| D | 0046306 | biological_process | alkanesulfonate catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue LLQ B 901 |
| Chain | Residue |
| B | ARG183 |
| B | ARG672 |
| B | ILE676 |
| B | HOH1086 |
| B | HOH1158 |
| B | HOH1289 |
| B | LEU186 |
| B | GLN187 |
| B | SER305 |
| B | ALA306 |
| B | TRP368 |
| B | GLY461 |
| B | CYS462 |
| B | GLU464 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 902 |
| Chain | Residue |
| B | ASP191 |
| B | ASN559 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 903 |
| Chain | Residue |
| B | TYR727 |
| B | ARG732 |
| D | HOH1204 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 904 |
| Chain | Residue |
| A | GLY59 |
| A | LEU61 |
| B | HIS150 |
| B | LEU544 |
| B | GLN547 |
| B | HOH1005 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 905 |
| Chain | Residue |
| B | LYS524 |
| B | ARG652 |
| B | PHE653 |
| B | GOL911 |
| B | HOH1129 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 906 |
| Chain | Residue |
| B | ARG65 |
| B | LYS145 |
| B | HIS548 |
| B | HOH1056 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 907 |
| Chain | Residue |
| B | ILE272 |
| B | ASN283 |
| B | ARG285 |
| B | GLU286 |
| B | HOH1040 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 908 |
| Chain | Residue |
| A | VAL154 |
| B | LEU64 |
| B | PRO227 |
| B | GLU230 |
| B | HOH1143 |
| B | HOH1200 |
| B | HOH1237 |
| B | HOH1395 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 909 |
| Chain | Residue |
| B | GLY448 |
| B | PRO450 |
| B | ARG470 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 910 |
| Chain | Residue |
| B | PRO378 |
| B | GLU379 |
| B | ASN452 |
| B | ASP456 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 911 |
| Chain | Residue |
| B | GLU521 |
| B | LYS524 |
| B | ASP649 |
| B | ARG652 |
| B | GOL905 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 912 |
| Chain | Residue |
| B | ASP221 |
| B | LYS225 |
| B | HOH1004 |
| B | HOH1196 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 913 |
| Chain | Residue |
| B | SER645 |
| B | LYS648 |
| B | HIS723 |
| B | HOH1041 |
| B | HOH1198 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 914 |
| Chain | Residue |
| B | ASP202 |
| B | ASN205 |
| B | GLU206 |
| B | HOH1011 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 915 |
| Chain | Residue |
| B | GLY666 |
| B | ILE667 |
| B | HIS668 |
| B | HOH1082 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue NA B 916 |
| Chain | Residue |
| B | THR472 |
| B | LEU568 |
| B | SER570 |
| B | HOH1067 |
| B | HOH1322 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 917 |
| Chain | Residue |
| B | ARG160 |
| B | GLY161 |
| B | ASP166 |
| B | GLU167 |
| site_id | AD9 |
| Number of Residues | 13 |
| Details | binding site for residue LLQ A 901 |
| Chain | Residue |
| A | ARG183 |
| A | LEU186 |
| A | GLN187 |
| A | SER305 |
| A | TRP368 |
| A | GLY461 |
| A | CYS462 |
| A | GLU464 |
| A | ARG672 |
| A | ILE676 |
| A | HOH1018 |
| A | HOH1264 |
| A | HOH1283 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 902 |
| Chain | Residue |
| A | GLN315 |
| A | HOH1093 |
| A | HOH1307 |
| A | GLU193 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 903 |
| Chain | Residue |
| A | PRO378 |
| A | ASN452 |
| A | ASP456 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 904 |
| Chain | Residue |
| A | GLY666 |
| A | ILE667 |
| A | HIS668 |
| site_id | AE4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 905 |
| Chain | Residue |
| A | ASN218 |
| A | SER219 |
| A | HOH1106 |
| B | PHE535 |
| B | GLU657 |
| B | SER661 |
| B | ASP664 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 906 |
| Chain | Residue |
| A | TYR727 |
| A | ARG732 |
| A | LYS766 |
| A | HOH1314 |
| C | HOH1142 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 907 |
| Chain | Residue |
| A | PRO227 |
| A | GLU230 |
| A | HOH1191 |
| A | HOH1356 |
| A | HOH1438 |
| B | VAL154 |
| site_id | AE7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 908 |
| Chain | Residue |
| A | GLU521 |
| A | LYS524 |
| A | ASP649 |
| A | ARG652 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 909 |
| Chain | Residue |
| A | LYS524 |
| A | ARG652 |
| A | HOH1140 |
| A | HOH1304 |
| site_id | AE9 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 910 |
| Chain | Residue |
| A | ASP202 |
| A | GLU206 |
| site_id | AF1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 911 |
| Chain | Residue |
| A | HIS150 |
| A | GLN547 |
| A | HOH1218 |
| B | GLY59 |
| B | LEU61 |
| site_id | AF2 |
| Number of Residues | 10 |
| Details | binding site for residue GOL A 912 |
| Chain | Residue |
| A | GLN532 |
| A | PHE535 |
| A | GLU657 |
| A | LYS660 |
| A | SER661 |
| A | ASP664 |
| A | HOH1004 |
| B | THR217 |
| B | ASN218 |
| B | SER219 |
| site_id | AF3 |
| Number of Residues | 1 |
| Details | binding site for residue GOL A 913 |
| site_id | AF4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 914 |
| Chain | Residue |
| A | ARG160 |
| A | TYR164 |
| A | HIS165 |
| A | ASP166 |
| A | HOH1024 |
| site_id | AF5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 915 |
| Chain | Residue |
| A | GLY448 |
| A | ARG470 |
| A | GLY575 |
| A | GLY576 |
| site_id | AF6 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 916 |
| Chain | Residue |
| A | THR472 |
| A | LEU568 |
| A | SER570 |
| A | HOH1148 |
| A | HOH1414 |
| site_id | AF7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 917 |
| Chain | Residue |
| A | TRP516 |
| A | TYR520 |
| A | SER645 |
| A | HOH1017 |
| A | HOH1172 |
| site_id | AF8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 918 |
| Chain | Residue |
| A | PHE174 |
| A | GLU360 |
| A | TYR497 |
| A | PRO681 |
| site_id | AF9 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 919 |
| Chain | Residue |
| A | GLN204 |
| A | LYS208 |
| A | ASP237 |
| A | HOH1350 |
| site_id | AG1 |
| Number of Residues | 14 |
| Details | binding site for residue LLQ C 901 |
| Chain | Residue |
| C | ARG183 |
| C | LEU186 |
| C | GLN187 |
| C | SER305 |
| C | ALA306 |
| C | TRP368 |
| C | GLY461 |
| C | CYS462 |
| C | GLU464 |
| C | ARG672 |
| C | ILE676 |
| C | HOH1094 |
| C | HOH1144 |
| C | HOH1155 |
| site_id | AG2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 902 |
| Chain | Residue |
| A | GLY728 |
| C | PRO378 |
| C | GLU379 |
| C | HOH1129 |
| site_id | AG3 |
| Number of Residues | 9 |
| Details | binding site for residue GOL C 903 |
| Chain | Residue |
| C | PHE535 |
| C | GLU657 |
| C | LYS660 |
| C | SER661 |
| C | ASP664 |
| D | ASN218 |
| D | SER219 |
| D | HOH1110 |
| D | HOH1294 |
| site_id | AG4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 904 |
| Chain | Residue |
| C | VAL154 |
| C | HOH1332 |
| D | GLU230 |
| D | GOL914 |
| D | HOH1138 |
| D | HOH1291 |
| site_id | AG5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 905 |
| Chain | Residue |
| C | GLU60 |
| C | GLU230 |
| C | HOH1076 |
| C | HOH1273 |
| D | VAL154 |
| site_id | AG6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 906 |
| Chain | Residue |
| C | GLN547 |
| C | HOH1206 |
| D | GLY59 |
| D | LEU61 |
| D | TRP223 |
| site_id | AG7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 907 |
| Chain | Residue |
| A | HOH1121 |
| A | HOH1348 |
| C | TYR727 |
| C | ARG732 |
| C | LYS766 |
| site_id | AG8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 908 |
| Chain | Residue |
| C | TYR520 |
| C | GLU521 |
| C | LYS524 |
| C | ASP649 |
| C | ARG652 |
| site_id | AG9 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 909 |
| Chain | Residue |
| C | LYS524 |
| C | ARG652 |
| C | PHE653 |
| C | HOH1045 |
| site_id | AH1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL C 910 |
| Chain | Residue |
| C | ASP701 |
| C | ALA705 |
| C | HIS707 |
| C | ASP814 |
| C | ARG818 |
| C | HOH1023 |
| C | HOH1184 |
| C | HOH1307 |
| site_id | AH2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 911 |
| Chain | Residue |
| C | SER662 |
| C | GLY666 |
| C | ILE667 |
| C | HIS668 |
| site_id | AH3 |
| Number of Residues | 5 |
| Details | binding site for residue NA C 912 |
| Chain | Residue |
| C | THR472 |
| C | LEU568 |
| C | SER570 |
| C | HOH1102 |
| C | HOH1344 |
| site_id | AH4 |
| Number of Residues | 13 |
| Details | binding site for residue LLQ D 901 |
| Chain | Residue |
| D | ARG183 |
| D | LEU186 |
| D | GLN187 |
| D | SER305 |
| D | TRP368 |
| D | GLY461 |
| D | CYS462 |
| D | GLU464 |
| D | ARG672 |
| D | ILE676 |
| D | HOH1153 |
| D | HOH1180 |
| D | HOH1285 |
| site_id | AH5 |
| Number of Residues | 7 |
| Details | binding site for residue GOL D 902 |
| Chain | Residue |
| D | GLU521 |
| D | LYS524 |
| D | ASP649 |
| D | ARG652 |
| D | GOL906 |
| D | GOL907 |
| D | HOH1113 |
| site_id | AH6 |
| Number of Residues | 9 |
| Details | binding site for residue GOL D 903 |
| Chain | Residue |
| D | ASP701 |
| D | SER704 |
| D | ASN738 |
| D | VAL797 |
| D | ALA798 |
| D | ASP814 |
| D | ARG818 |
| D | HOH1078 |
| D | HOH1162 |
| site_id | AH7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 904 |
| Chain | Residue |
| D | PRO378 |
| D | ASN452 |
| D | GLU453 |
| D | ASP456 |
| D | HOH1319 |
| site_id | AH8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 905 |
| Chain | Residue |
| D | ARG65 |
| D | TRP142 |
| D | LYS145 |
| D | HIS548 |
| D | HOH1112 |
| D | HOH1259 |
| site_id | AH9 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 906 |
| Chain | Residue |
| D | LYS524 |
| D | ARG652 |
| D | PHE653 |
| D | GOL902 |
| D | HOH1087 |
| D | HOH1113 |
| site_id | AI1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL D 907 |
| Chain | Residue |
| D | TRP516 |
| D | LYS598 |
| D | SER645 |
| D | ILE646 |
| D | GOL902 |
| D | HOH1013 |
| D | HOH1024 |
| site_id | AI2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 908 |
| Chain | Residue |
| C | GLY59 |
| C | LEU61 |
| D | HIS150 |
| D | GLN547 |
| D | HOH1028 |
| site_id | AI3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 909 |
| Chain | Residue |
| B | HOH1233 |
| D | TYR727 |
| D | ARG732 |
| D | LYS766 |
| D | HOH1170 |
| site_id | AI4 |
| Number of Residues | 1 |
| Details | binding site for residue GOL D 910 |
| site_id | AI5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL D 911 |
| Chain | Residue |
| D | ARG160 |
| D | TYR164 |
| D | HIS165 |
| D | ASP166 |
| site_id | AI6 |
| Number of Residues | 5 |
| Details | binding site for residue NA D 912 |
| Chain | Residue |
| D | THR472 |
| D | LEU568 |
| D | SER570 |
| D | HOH1195 |
| D | HOH1354 |
| site_id | AI7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL D 913 |
| Chain | Residue |
| C | THR217 |
| C | ASN218 |
| C | SER219 |
| D | PHE535 |
| D | GLU657 |
| D | HOH1007 |
| D | HOH1093 |
| site_id | AI8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL D 914 |
| Chain | Residue |
| C | GOL904 |
| D | LEU64 |
| D | LYS68 |
| D | GLU230 |
Functional Information from PROSITE/UniProt
| site_id | PS00850 |
| Number of Residues | 9 |
| Details | GLY_RADICAL_1 Glycine radical domain signature. IvRVAGYSA |
| Chain | Residue | Details |
| B | ILE794-ALA802 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2672 |
| Details | Domain: {"description":"PFL","evidences":[{"source":"PROSITE-ProRule","id":"PRU00887","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Cysteine radical intermediate","evidences":[{"source":"PubMed","id":"32571930","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"32571930","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"32571930","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Glycine radical","evidences":[{"source":"PROSITE-ProRule","id":"PRU00493","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 369 |
| Details | Domain: {"description":"Glycine radical","evidences":[{"source":"PROSITE-ProRule","id":"PRU00493","evidenceCode":"ECO:0000255"}]} |
