6LO0
The co-crystal structure of Severe Acute Respiratory Syndrome Coronavirus 3C Like Protease with aldehyde M14
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue EOF A 401 |
| Chain | Residue |
| A | PHE140 |
| A | GLN189 |
| A | THR190 |
| A | ALA191 |
| A | HOH501 |
| A | HOH593 |
| A | ASN142 |
| A | CYS145 |
| A | HIS163 |
| A | HIS164 |
| A | MET165 |
| A | GLU166 |
| A | HIS172 |
| A | ASP187 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: For 3CL-PRO activity => ECO:0000255|PROSITE-ProRule:PRU00772, ECO:0000269|PubMed:16306590 |
| Chain | Residue | Details |
| A | HIS41 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: For 3CL-PRO activity => ECO:0000255|PROSITE-ProRule:PRU00772 |
| Chain | Residue | Details |
| A | CYS145 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Cleavage; by 3CL-PRO => ECO:0000269|PubMed:14561748 |
| Chain | Residue | Details |
| A | GLN306 |
