6LNT
Cryo-EM structure of immature Zika virus in complex with human antibody DV62.5 Fab
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0046983 | molecular_function | protein dimerization activity |
| B | 0046983 | molecular_function | protein dimerization activity |
| C | 0046983 | molecular_function | protein dimerization activity |
| D | 0019058 | biological_process | viral life cycle |
| E | 0019058 | biological_process | viral life cycle |
| F | 0019058 | biological_process | viral life cycle |
| M | 0005198 | molecular_function | structural molecule activity |
| M | 0019028 | cellular_component | viral capsid |
| N | 0005198 | molecular_function | structural molecule activity |
| N | 0019028 | cellular_component | viral capsid |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease NS3 => ECO:0000250|UniProtKB:Q32ZE1 |
| Chain | Residue | Details |
| M | ARG99 | |
| N | ARG99 | |
| F | TRP123-GLY142 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by host signal peptidase => ECO:0000250|UniProtKB:Q32ZE1 |
| Chain | Residue | Details |
| M | ALA117 | |
| N | ALA117 | |
| F | SER143-GLN147 | |
| B | ILE484-ALA504 | |
| C | LEU456-LEU477 | |
| C | ILE484-ALA504 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 45 |
| Details | TRANSMEM: Helical => ECO:0000305 |
| Chain | Residue | Details |
| D | LYS148-SER163 | |
| E | LYS148-SER163 | |
| F | LYS148-SER163 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | SITE: Fetal microcephaly |
| Chain | Residue | Details |
| D | ASN12 | |
| E | ASN12 | |
| F | ASN12 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host furin => ECO:0000250|UniProtKB:Q32ZE1 |
| Chain | Residue | Details |
| D | ARG88 | |
| E | ARG88 | |
| F | ARG88 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by host signal peptidase => ECO:0000250|UniProtKB:P06935 |
| Chain | Residue | Details |
| D | SER163 | |
| E | SER163 | |
| F | SER163 | |
| B | LYS38 | |
| B | LYS281 | |
| C | LYS38 | |
| C | LYS281 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255 |
| Chain | Residue | Details |
| D | ASN65 | |
| E | ASN65 | |
| F | ASN65 |
