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6LMU

Cryo-EM structure of the human CALHM2

Functional Information from GO Data
ChainGOidnamespacecontents
A0005261molecular_functionmonoatomic cation channel activity
A0006811biological_processmonoatomic ion transport
A0016020cellular_componentmembrane
A0034220biological_processmonoatomic ion transmembrane transport
A0043065biological_processpositive regulation of apoptotic process
A0098655biological_processmonoatomic cation transmembrane transport
B0005261molecular_functionmonoatomic cation channel activity
B0006811biological_processmonoatomic ion transport
B0016020cellular_componentmembrane
B0034220biological_processmonoatomic ion transmembrane transport
B0043065biological_processpositive regulation of apoptotic process
B0098655biological_processmonoatomic cation transmembrane transport
C0005261molecular_functionmonoatomic cation channel activity
C0006811biological_processmonoatomic ion transport
C0016020cellular_componentmembrane
C0034220biological_processmonoatomic ion transmembrane transport
C0043065biological_processpositive regulation of apoptotic process
C0098655biological_processmonoatomic cation transmembrane transport
D0005261molecular_functionmonoatomic cation channel activity
D0006811biological_processmonoatomic ion transport
D0016020cellular_componentmembrane
D0034220biological_processmonoatomic ion transmembrane transport
D0043065biological_processpositive regulation of apoptotic process
D0098655biological_processmonoatomic cation transmembrane transport
E0005261molecular_functionmonoatomic cation channel activity
E0006811biological_processmonoatomic ion transport
E0016020cellular_componentmembrane
E0034220biological_processmonoatomic ion transmembrane transport
E0043065biological_processpositive regulation of apoptotic process
E0098655biological_processmonoatomic cation transmembrane transport
F0005261molecular_functionmonoatomic cation channel activity
F0006811biological_processmonoatomic ion transport
F0016020cellular_componentmembrane
F0034220biological_processmonoatomic ion transmembrane transport
F0043065biological_processpositive regulation of apoptotic process
F0098655biological_processmonoatomic cation transmembrane transport
G0005261molecular_functionmonoatomic cation channel activity
G0006811biological_processmonoatomic ion transport
G0016020cellular_componentmembrane
G0034220biological_processmonoatomic ion transmembrane transport
G0043065biological_processpositive regulation of apoptotic process
G0098655biological_processmonoatomic cation transmembrane transport
H0005261molecular_functionmonoatomic cation channel activity
H0006811biological_processmonoatomic ion transport
H0016020cellular_componentmembrane
H0034220biological_processmonoatomic ion transmembrane transport
H0043065biological_processpositive regulation of apoptotic process
H0098655biological_processmonoatomic cation transmembrane transport
I0005261molecular_functionmonoatomic cation channel activity
I0006811biological_processmonoatomic ion transport
I0016020cellular_componentmembrane
I0034220biological_processmonoatomic ion transmembrane transport
I0043065biological_processpositive regulation of apoptotic process
I0098655biological_processmonoatomic cation transmembrane transport
J0005261molecular_functionmonoatomic cation channel activity
J0006811biological_processmonoatomic ion transport
J0016020cellular_componentmembrane
J0034220biological_processmonoatomic ion transmembrane transport
J0043065biological_processpositive regulation of apoptotic process
J0098655biological_processmonoatomic cation transmembrane transport
K0005261molecular_functionmonoatomic cation channel activity
K0006811biological_processmonoatomic ion transport
K0016020cellular_componentmembrane
K0034220biological_processmonoatomic ion transmembrane transport
K0043065biological_processpositive regulation of apoptotic process
K0098655biological_processmonoatomic cation transmembrane transport
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues880
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
AVAL21-VAL41
CLEU55-LEU75
CPHE100-ILE120
CGLN185-LEU205
DVAL21-VAL41
DLEU55-LEU75
DPHE100-ILE120
DGLN185-LEU205
EVAL21-VAL41
ELEU55-LEU75
EPHE100-ILE120
ALEU55-LEU75
EGLN185-LEU205
FVAL21-VAL41
FLEU55-LEU75
FPHE100-ILE120
FGLN185-LEU205
GVAL21-VAL41
GLEU55-LEU75
GPHE100-ILE120
GGLN185-LEU205
HVAL21-VAL41
APHE100-ILE120
HLEU55-LEU75
HPHE100-ILE120
HGLN185-LEU205
IVAL21-VAL41
ILEU55-LEU75
IPHE100-ILE120
IGLN185-LEU205
JVAL21-VAL41
JLEU55-LEU75
JPHE100-ILE120
AGLN185-LEU205
JGLN185-LEU205
KVAL21-VAL41
KLEU55-LEU75
KPHE100-ILE120
KGLN185-LEU205
BVAL21-VAL41
BLEU55-LEU75
BPHE100-ILE120
BGLN185-LEU205
CVAL21-VAL41

218853

PDB entries from 2024-04-24

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