6LMT
Cryo-EM structure of the killifish CALHM1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005227 | molecular_function | calcium activated cation channel activity |
| A | 0005244 | molecular_function | voltage-gated ion channel activity |
| A | 0006812 | biological_process | cation transport |
| B | 0005227 | molecular_function | calcium activated cation channel activity |
| B | 0005244 | molecular_function | voltage-gated ion channel activity |
| B | 0006812 | biological_process | cation transport |
| C | 0005227 | molecular_function | calcium activated cation channel activity |
| C | 0005244 | molecular_function | voltage-gated ion channel activity |
| C | 0006812 | biological_process | cation transport |
| D | 0005227 | molecular_function | calcium activated cation channel activity |
| D | 0005244 | molecular_function | voltage-gated ion channel activity |
| D | 0006812 | biological_process | cation transport |
| E | 0005227 | molecular_function | calcium activated cation channel activity |
| E | 0005244 | molecular_function | voltage-gated ion channel activity |
| E | 0006812 | biological_process | cation transport |
| F | 0005227 | molecular_function | calcium activated cation channel activity |
| F | 0005244 | molecular_function | voltage-gated ion channel activity |
| F | 0006812 | biological_process | cation transport |
| G | 0005227 | molecular_function | calcium activated cation channel activity |
| G | 0005244 | molecular_function | voltage-gated ion channel activity |
| G | 0006812 | biological_process | cation transport |
| H | 0005227 | molecular_function | calcium activated cation channel activity |
| H | 0005244 | molecular_function | voltage-gated ion channel activity |
| H | 0006812 | biological_process | cation transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue Y01 A 401 |
| Chain | Residue |
| A | MET33 |
| B | VAL116 |
| B | MET119 |
| B | Y01401 |
| B | Y01404 |
| A | SER36 |
| A | TRP62 |
| A | LEU66 |
| A | VAL69 |
| B | MET19 |
| B | ALA111 |
| B | VAL112 |
| B | SER115 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue Y01 A 402 |
| Chain | Residue |
| A | TYR49 |
| A | ILE53 |
| A | LEU56 |
| A | PHE128 |
| A | ASN131 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue Y01 A 403 |
| Chain | Residue |
| A | MET19 |
| A | GLN104 |
| A | LEU107 |
| A | ILE108 |
| A | MET192 |
| A | ILE199 |
| A | ARG200 |
| A | ARG203 |
| A | Y01404 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | binding site for residue Y01 A 404 |
| Chain | Residue |
| A | MET19 |
| A | ALA111 |
| A | VAL112 |
| A | SER115 |
| A | VAL116 |
| A | MET119 |
| A | Y01403 |
| A | Y01405 |
| H | MET33 |
| H | SER36 |
| H | TRP62 |
| H | LEU66 |
| H | VAL69 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue Y01 A 405 |
| Chain | Residue |
| A | MET7 |
| A | ALA27 |
| A | LEU28 |
| A | ALA31 |
| A | SER35 |
| A | Y01404 |
| H | SER36 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue Y01 B 401 |
| Chain | Residue |
| A | SER36 |
| A | Y01401 |
| B | MET7 |
| B | ALA27 |
| B | LEU28 |
| B | ALA31 |
| B | SER35 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | binding site for residue Y01 B 402 |
| Chain | Residue |
| B | MET33 |
| B | SER36 |
| B | TRP62 |
| B | LEU66 |
| B | VAL69 |
| C | MET19 |
| C | ALA111 |
| C | VAL112 |
| C | SER115 |
| C | VAL116 |
| C | MET119 |
| C | Y01401 |
| C | Y01404 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue Y01 B 403 |
| Chain | Residue |
| B | TYR49 |
| B | ILE53 |
| B | LEU56 |
| B | PHE128 |
| B | ASN131 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue Y01 B 404 |
| Chain | Residue |
| A | Y01401 |
| B | MET19 |
| B | GLN104 |
| B | LEU107 |
| B | ILE108 |
| B | MET192 |
| B | ILE199 |
| B | ARG200 |
| B | ARG203 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue Y01 C 401 |
| Chain | Residue |
| B | SER36 |
| B | Y01402 |
| C | MET7 |
| C | ALA27 |
| C | LEU28 |
| C | ALA31 |
| C | SER35 |
| site_id | AD2 |
| Number of Residues | 13 |
| Details | binding site for residue Y01 C 402 |
| Chain | Residue |
| D | Y01401 |
| D | Y01404 |
| C | MET33 |
| C | SER36 |
| C | TRP62 |
| C | LEU66 |
| C | VAL69 |
| D | MET19 |
| D | ALA111 |
| D | VAL112 |
| D | SER115 |
| D | VAL116 |
| D | MET119 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue Y01 C 403 |
| Chain | Residue |
| C | TYR49 |
| C | ILE53 |
| C | LEU56 |
| C | PHE128 |
| C | ASN131 |
| site_id | AD4 |
| Number of Residues | 9 |
| Details | binding site for residue Y01 C 404 |
| Chain | Residue |
| B | Y01402 |
| C | MET19 |
| C | GLN104 |
| C | LEU107 |
| C | ILE108 |
| C | MET192 |
| C | ILE199 |
| C | ARG200 |
| C | ARG203 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue Y01 D 401 |
| Chain | Residue |
| C | SER36 |
| C | Y01402 |
| D | MET7 |
| D | ALA27 |
| D | LEU28 |
| D | ALA31 |
| D | SER35 |
| site_id | AD6 |
| Number of Residues | 13 |
| Details | binding site for residue Y01 D 402 |
| Chain | Residue |
| D | MET33 |
| D | SER36 |
| D | TRP62 |
| D | LEU66 |
| D | VAL69 |
| E | MET19 |
| E | ALA111 |
| E | VAL112 |
| E | SER115 |
| E | VAL116 |
| E | MET119 |
| E | Y01401 |
| E | Y01404 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue Y01 D 403 |
| Chain | Residue |
| D | TYR49 |
| D | ILE53 |
| D | LEU56 |
| D | PHE128 |
| D | ASN131 |
| site_id | AD8 |
| Number of Residues | 9 |
| Details | binding site for residue Y01 D 404 |
| Chain | Residue |
| C | Y01402 |
| D | MET19 |
| D | GLN104 |
| D | LEU107 |
| D | ILE108 |
| D | MET192 |
| D | ILE199 |
| D | ARG200 |
| D | ARG203 |
| site_id | AD9 |
| Number of Residues | 7 |
| Details | binding site for residue Y01 E 401 |
| Chain | Residue |
| D | SER36 |
| D | Y01402 |
| E | MET7 |
| E | ALA27 |
| E | LEU28 |
| E | ALA31 |
| E | SER35 |
| site_id | AE1 |
| Number of Residues | 13 |
| Details | binding site for residue Y01 E 402 |
| Chain | Residue |
| E | MET33 |
| E | SER36 |
| E | TRP62 |
| E | LEU66 |
| E | VAL69 |
| F | MET19 |
| F | ALA111 |
| F | VAL112 |
| F | SER115 |
| F | VAL116 |
| F | MET119 |
| F | Y01401 |
| F | Y01404 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue Y01 E 403 |
| Chain | Residue |
| E | TYR49 |
| E | ILE53 |
| E | LEU56 |
| E | PHE128 |
| E | ASN131 |
| site_id | AE3 |
| Number of Residues | 9 |
| Details | binding site for residue Y01 E 404 |
| Chain | Residue |
| D | Y01402 |
| E | MET19 |
| E | GLN104 |
| E | LEU107 |
| E | ILE108 |
| E | MET192 |
| E | ILE199 |
| E | ARG200 |
| E | ARG203 |
| site_id | AE4 |
| Number of Residues | 7 |
| Details | binding site for residue Y01 F 401 |
| Chain | Residue |
| E | SER36 |
| E | Y01402 |
| F | MET7 |
| F | ALA27 |
| F | LEU28 |
| F | ALA31 |
| F | SER35 |
| site_id | AE5 |
| Number of Residues | 13 |
| Details | binding site for residue Y01 F 402 |
| Chain | Residue |
| F | MET33 |
| F | SER36 |
| F | TRP62 |
| F | LEU66 |
| F | VAL69 |
| G | MET19 |
| G | ALA111 |
| G | VAL112 |
| G | SER115 |
| G | VAL116 |
| G | MET119 |
| G | Y01401 |
| G | Y01404 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue Y01 F 403 |
| Chain | Residue |
| F | TYR49 |
| F | ILE53 |
| F | LEU56 |
| F | PHE128 |
| F | ASN131 |
| site_id | AE7 |
| Number of Residues | 9 |
| Details | binding site for residue Y01 F 404 |
| Chain | Residue |
| E | Y01402 |
| F | MET19 |
| F | GLN104 |
| F | LEU107 |
| F | ILE108 |
| F | MET192 |
| F | ILE199 |
| F | ARG200 |
| F | ARG203 |
| site_id | AE8 |
| Number of Residues | 7 |
| Details | binding site for residue Y01 G 401 |
| Chain | Residue |
| F | SER36 |
| F | Y01402 |
| G | MET7 |
| G | ALA27 |
| G | LEU28 |
| G | ALA31 |
| G | SER35 |
| site_id | AE9 |
| Number of Residues | 13 |
| Details | binding site for residue Y01 G 402 |
| Chain | Residue |
| G | MET33 |
| G | SER36 |
| G | TRP62 |
| G | LEU66 |
| G | VAL69 |
| H | MET19 |
| H | ALA111 |
| H | VAL112 |
| H | SER115 |
| H | VAL116 |
| H | MET119 |
| H | Y01401 |
| H | Y01403 |
| site_id | AF1 |
| Number of Residues | 5 |
| Details | binding site for residue Y01 G 403 |
| Chain | Residue |
| G | TYR49 |
| G | ILE53 |
| G | LEU56 |
| G | PHE128 |
| G | ASN131 |
| site_id | AF2 |
| Number of Residues | 9 |
| Details | binding site for residue Y01 G 404 |
| Chain | Residue |
| F | Y01402 |
| G | MET19 |
| G | GLN104 |
| G | LEU107 |
| G | ILE108 |
| G | MET192 |
| G | ILE199 |
| G | ARG200 |
| G | ARG203 |
| site_id | AF3 |
| Number of Residues | 7 |
| Details | binding site for residue Y01 H 401 |
| Chain | Residue |
| G | SER36 |
| G | Y01402 |
| H | MET7 |
| H | ALA27 |
| H | LEU28 |
| H | ALA31 |
| H | SER35 |
| site_id | AF4 |
| Number of Residues | 5 |
| Details | binding site for residue Y01 H 402 |
| Chain | Residue |
| H | TYR49 |
| H | ILE53 |
| H | LEU56 |
| H | PHE128 |
| H | ASN131 |
| site_id | AF5 |
| Number of Residues | 9 |
| Details | binding site for residue Y01 H 403 |
| Chain | Residue |
| G | Y01402 |
| H | MET19 |
| H | GLN104 |
| H | LEU107 |
| H | ILE108 |
| H | MET192 |
| H | ILE199 |
| H | ARG200 |
| H | ARG203 |
