Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6LM1

The crystal structure of cyanorhodopsin (CyR) N4075R from cyanobacteria Tolypothrix sp. NIES-4075

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005216	molecular_function	monoatomic ion channel activity
A	0006811	biological_process	monoatomic ion transport
A	0007602	biological_process	phototransduction
A	0009881	molecular_function	photoreceptor activity
A	0016020	cellular_component	membrane
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0046872	molecular_function	metal ion binding
B	0005216	molecular_function	monoatomic ion channel activity
B	0006811	biological_process	monoatomic ion transport
B	0007602	biological_process	phototransduction
B	0009881	molecular_function	photoreceptor activity
B	0016020	cellular_component	membrane
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0046872	molecular_function	metal ion binding
C	0005216	molecular_function	monoatomic ion channel activity
C	0006811	biological_process	monoatomic ion transport
C	0007602	biological_process	phototransduction
C	0009881	molecular_function	photoreceptor activity
C	0016020	cellular_component	membrane
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue RET A 301

Chain	Residue
A	TRP78
A	LYS207
A	THR82
A	TYR129
A	SER132
A	PHE136
A	TRP173
A	TYR176
A	PRO177
A	ASP203

site_id	AC2
Number of Residues	7
Details	binding site for residue MG A 302

Chain	Residue
A	THR118
A	GLU120
A	GLU185
A	HOH403
A	HOH420
A	HOH424
A	HOH445

site_id	AC3
Number of Residues	2
Details	binding site for residue HEX A 303

Chain	Residue
A	LEU119
A	GLU120

site_id	AC4
Number of Residues	2
Details	binding site for residue HEX A 304

Chain	Residue
A	ILE204
A	D12318

site_id	AC5
Number of Residues	2
Details	binding site for residue HEX A 306

Chain	Residue
A	SER216
A	D12318

site_id	AC6
Number of Residues	1
Details	binding site for residue HEX A 307

Chain	Residue
A	D12319

site_id	AC7
Number of Residues	1
Details	binding site for residue OCT A 308

Chain	Residue
A	TRP72

site_id	AC8
Number of Residues	4
Details	binding site for residue OCT A 309

Chain	Residue
A	PRO123
A	THR124
A	ILE130
B	D12318

site_id	AC9
Number of Residues	4
Details	binding site for residue OCT A 311

Chain	Residue
A	GLU37
A	LEU40
A	PHE44
C	LYS98

site_id	AD1
Number of Residues	1
Details	binding site for residue OCT A 312

Chain	Residue
B	OCT310

site_id	AD2
Number of Residues	1
Details	binding site for residue OCT A 313

Chain	Residue
A	TRP10

site_id	AD3
Number of Residues	1
Details	binding site for residue OCT A 314

Chain	Residue
A	VAL79

site_id	AD4
Number of Residues	1
Details	binding site for residue OCT A 315

Chain	Residue
A	C14325

site_id	AD5
Number of Residues	1
Details	binding site for residue D10 A 316

Chain	Residue
C	PHE187

site_id	AD6
Number of Residues	5
Details	binding site for residue D12 A 318

Chain	Residue
A	ILE204
A	VAL208
A	GLY209
A	HEX304
A	HEX306

site_id	AD7
Number of Residues	2
Details	binding site for residue D12 A 319

Chain	Residue
A	ILE201
A	HEX307

site_id	AD8
Number of Residues	5
Details	binding site for residue R16 A 320

Chain	Residue
A	TYR126
A	TYR129
A	ILE130
A	CYS133
A	PHE187

site_id	AD9
Number of Residues	2
Details	binding site for residue R16 A 321

Chain	Residue
A	LYS164
A	ASN167

site_id	AE1
Number of Residues	1
Details	binding site for residue R16 A 322

Chain	Residue
A	ILE104

site_id	AE2
Number of Residues	4
Details	binding site for residue R16 A 323

Chain	Residue
A	ILE131
A	ALA138
A	GLU146
B	ARG31

site_id	AE3
Number of Residues	6
Details	binding site for residue R16 A 324

Chain	Residue
A	PRO191
A	ILE198
C	LYS164
C	ASN167
C	LEU172
C	R16321

site_id	AE4
Number of Residues	3
Details	binding site for residue C14 A 325

Chain	Residue
A	TRP10
A	OCT315
B	OCT310

site_id	AE5
Number of Residues	6
Details	binding site for residue MG B 302

Chain	Residue
B	THR118
B	HOH403
B	HOH421
B	HOH439
B	HOH447
B	HOH448

site_id	AE6
Number of Residues	1
Details	binding site for residue HEX B 303

Chain	Residue
B	ILE204

site_id	AE7
Number of Residues	1
Details	binding site for residue HEX B 304

Chain	Residue
B	C14320

site_id	AE8
Number of Residues	2
Details	binding site for residue HEX B 305

Chain	Residue
B	LYS164
B	TYR168

site_id	AE9
Number of Residues	2
Details	binding site for residue HEX B 306

Chain	Residue
A	SER216
B	PHE187

site_id	AF1
Number of Residues	1
Details	binding site for residue HEX B 307

Chain	Residue
B	OCT310

site_id	AF2
Number of Residues	2
Details	binding site for residue OCT B 308

Chain	Residue
B	PRO123
B	THR124

site_id	AF3
Number of Residues	4
Details	binding site for residue OCT B 310

Chain	Residue
A	OCT312
A	C14325
B	HEX307
B	OCT312

site_id	AF4
Number of Residues	1
Details	binding site for residue OCT B 311

Chain	Residue
B	TYR129

site_id	AF5
Number of Residues	2
Details	binding site for residue OCT B 312

Chain	Residue
B	TYR168
B	OCT310

site_id	AF6
Number of Residues	1
Details	binding site for residue D10 B 314

Chain	Residue
B	VAL79

site_id	AF7
Number of Residues	2
Details	binding site for residue D12 B 316

Chain	Residue
B	TYR129
B	CYS133

site_id	AF8
Number of Residues	4
Details	binding site for residue D12 B 317

Chain	Residue
B	ILE131
B	SER142
C	PHE43
C	PHE44

site_id	AF9
Number of Residues	1
Details	binding site for residue D12 B 318

Chain	Residue
A	OCT309

site_id	AG1
Number of Residues	1
Details	binding site for residue R16 B 319

Chain	Residue
C	TRP48

site_id	AG2
Number of Residues	3
Details	binding site for residue C14 B 320

Chain	Residue
B	HEX304
B	TRP10
B	ILE14

site_id	AG3
Number of Residues	7
Details	binding site for residue MG C 302

Chain	Residue
C	THR118
C	GLU120
C	GLU185
C	HOH403
C	HOH412
C	HOH413
C	HOH440

site_id	AG4
Number of Residues	3
Details	binding site for residue HEX C 304

Chain	Residue
A	TRP48
A	ALA51
C	THR113

site_id	AG5
Number of Residues	2
Details	binding site for residue HEX C 306

Chain	Residue
B	THR113
C	TRP48

site_id	AG6
Number of Residues	2
Details	binding site for residue HEX C 307

Chain	Residue
C	OCT314
C	R16321

site_id	AG7
Number of Residues	1
Details	binding site for residue HEX C 308

Chain	Residue
C	D12318

site_id	AG8
Number of Residues	2
Details	binding site for residue HEX C 309

Chain	Residue
C	ILE14
C	R16319

site_id	AG9
Number of Residues	1
Details	binding site for residue HEX C 310

Chain	Residue
C	PHE44

site_id	AH1
Number of Residues	1
Details	binding site for residue HEX C 312

Chain	Residue
C	TRP72

site_id	AH2
Number of Residues	2
Details	binding site for residue OCT C 314

Chain	Residue
C	ILE204
C	HEX307

site_id	AH3
Number of Residues	1
Details	binding site for residue OCT C 316

Chain	Residue
C	VAL79

site_id	AH4
Number of Residues	2
Details	binding site for residue OCT C 317

Chain	Residue
C	PRO123
C	THR124

site_id	AH5
Number of Residues	4
Details	binding site for residue D12 C 318

Chain	Residue
C	TYR126
C	ALA186
C	PHE187
C	HEX308

site_id	AH6
Number of Residues	3
Details	binding site for residue R16 C 319

Chain	Residue
C	TRP10
C	ILE14
C	HEX309

site_id	AH7
Number of Residues	1
Details	binding site for residue R16 C 320

Chain	Residue
A	TRP48

site_id	AH8
Number of Residues	4
Details	binding site for residue R16 C 321

Chain	Residue
A	R16324
C	ILE198
C	ILE201
C	HEX307

site_id	AH9
Number of Residues	6
Details	binding site for residue NO3 C 322

Chain	Residue
C	MET1
C	THR2
C	ALA5
C	PHE71
C	THR192
C	GLY193

site_id	AI1
Number of Residues	6
Details	binding site for residue NO3 C 323

Chain	Residue
C	THR2
C	LEU4
C	PRO191
C	THR192
C	GLY193
C	VAL194

site_id	AI2
Number of Residues	1
Details	binding site for residue C14 C 324

Chain	Residue
C	SER216

site_id	AI3
Number of Residues	21
Details	binding site for Di-peptide RET B 301 and LYS B 207

Chain	Residue
B	MET16
B	ILE45
B	ASP77
B	TRP78
B	THR81
B	THR82
B	TYR129
B	SER132
B	PHE136
B	TRP173
B	TYR176
B	PRO177
B	ASP203
B	ILE204
B	ALA205
B	ALA206
B	VAL208
B	GLY209
B	GLY211
B	HOH402
B	HOH419

site_id	AI4
Number of Residues	22
Details	binding site for Di-peptide RET C 301 and LYS C 207

Chain	Residue
C	MET16
C	ILE45
C	ASP77
C	TRP78
C	THR81
C	THR82
C	MET110
C	TYR129
C	SER132
C	PHE136
C	TRP173
C	TYR176
C	PRO177
C	ASP203
C	ILE204
C	ALA205
C	ALA206
C	VAL208
C	GLY209
C	GLY211
C	HOH404
C	HOH436

Functional Information from PROSITE/UniProt

site_id	PS00950
Number of Residues	13
Details	BACTERIAL_OPSIN_1 Bacterial rhodopsins signature 1. RYvDWvVTTPVLL

Chain	Residue	Details
A	ARG74-LEU86

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)