Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue FES A 401 |
| Chain | Residue |
| A | CYS69 |
| A | HIS71 |
| A | ARG72 |
| A | CYS90 |
| A | TYR92 |
| A | HIS93 |
| A | TRP95 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue FE A 402 |
| Chain | Residue |
| A | ASP333 |
| A | EHX403 |
| A | HIS183 |
| A | HIS187 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue EHX A 403 |
| Chain | Residue |
| A | GLY178 |
| A | HIS183 |
| A | HIS187 |
| A | ALA259 |
| A | ILE262 |
| A | LEU270 |
| A | PHE275 |
| A | GLN282 |
| A | GLU284 |
| A | PHE329 |
| A | ASN330 |
| A | ASP333 |
| A | FE402 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | ASN170 |
| A | ARG172 |
| A | GLU291 |
| A | HOH520 |
| A | HOH604 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 405 |
| Chain | Residue |
| A | ARG68 |
| A | CYS69 |
| A | LEU70 |
| B | PHE343 |
| B | ASN352 |
| B | ILE354 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 406 |
| Chain | Residue |
| A | TRP29 |
| A | VAL126 |
| C | HIS234 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 407 |
| Chain | Residue |
| A | ARG26 |
| A | GLU51 |
| A | LYS66 |
| A | TYR124 |
| A | HIS381 |
| A | HOH554 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 408 |
| Chain | Residue |
| A | THR84 |
| A | SER86 |
| B | ILE243 |
| B | GLU246 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 409 |
| Chain | Residue |
| A | PHE34 |
| A | LYS36 |
| A | GLY131 |
| A | ILE160 |
| A | GLY162 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 410 |
| Chain | Residue |
| A | LYS256 |
| A | ASN277 |
| A | PRO278 |
| A | PGE413 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue PEG A 411 |
| Chain | Residue |
| A | LYS194 |
| A | ASP197 |
| A | HIS372 |
| A | ASN373 |
| A | PEG412 |
| site_id | AD3 |
| Number of Residues | 8 |
| Details | binding site for residue PEG A 412 |
| Chain | Residue |
| A | PRO17 |
| A | SER370 |
| A | GLU371 |
| A | ASN373 |
| A | GLY375 |
| A | ILE376 |
| A | PEG411 |
| A | HOH578 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue PGE A 413 |
| Chain | Residue |
| A | ASP195 |
| A | ASN196 |
| A | LYS320 |
| A | PEG410 |
| A | HOH599 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue PGE A 414 |
| Chain | Residue |
| A | LYS85 |
| A | GLU100 |
| B | THR112 |
| C | ALA205 |
| C | VAL236 |
| C | PHE239 |
| C | GLU240 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue PGE A 415 |
| Chain | Residue |
| A | ARG98 |
| A | ILE116 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 416 |
| Chain | Residue |
| A | ARG147 |
| A | ASP195 |
| A | GLN374 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue FES B 401 |
| Chain | Residue |
| B | CYS69 |
| B | HIS71 |
| B | ARG72 |
| B | CYS90 |
| B | TYR92 |
| B | HIS93 |
| B | TRP95 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue FE B 402 |
| Chain | Residue |
| B | HIS183 |
| B | HIS187 |
| B | ASP333 |
| B | 9G0403 |
| site_id | AE1 |
| Number of Residues | 11 |
| Details | binding site for residue 9G0 B 403 |
| Chain | Residue |
| B | ILE184 |
| B | HIS187 |
| B | ALA259 |
| B | VAL272 |
| B | PHE275 |
| B | GLN282 |
| B | ASN330 |
| B | ASP333 |
| B | FE402 |
| B | HOH530 |
| B | HIS183 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 404 |
| Chain | Residue |
| B | ASP197 |
| B | TYR253 |
| B | HOH544 |
| B | HOH565 |
| B | HOH568 |
| B | HOH585 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 405 |
| Chain | Residue |
| B | TRP335 |
| B | GLU338 |
| B | EDO413 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 407 |
| Chain | Residue |
| B | TRP350 |
| B | VAL351 |
| B | GLU353 |
| B | LEU355 |
| B | HOH515 |
| site_id | AE5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 408 |
| Chain | Residue |
| B | GLY50 |
| B | GLU51 |
| B | ASN52 |
| B | LYS66 |
| B | VAL382 |
| B | PGE421 |
| B | HOH584 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 409 |
| Chain | Residue |
| B | CYS105 |
| B | ASP106 |
| B | DMS423 |
| C | GLY244 |
| site_id | AE7 |
| Number of Residues | 10 |
| Details | binding site for residue EDO B 410 |
| Chain | Residue |
| B | GLY41 |
| B | ASN56 |
| B | ILE58 |
| B | CYS82 |
| B | THR84 |
| B | LYS85 |
| B | SER86 |
| B | THR87 |
| B | TRP99 |
| B | HOH523 |
| site_id | AE8 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 411 |
| site_id | AE9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 412 |
| Chain | Residue |
| B | GLU255 |
| B | LYS256 |
| B | ILE257 |
| site_id | AF1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 413 |
| Chain | Residue |
| B | ILE166 |
| B | ILE167 |
| B | LYS168 |
| B | GLU338 |
| B | EDO405 |
| site_id | AF2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 414 |
| Chain | Residue |
| B | LYS163 |
| B | GLN165 |
| B | LEU326 |
| B | GLU327 |
| B | ASN331 |
| B | ILE334 |
| site_id | AF3 |
| Number of Residues | 6 |
| Details | binding site for residue PEG B 415 |
| Chain | Residue |
| A | LYS211 |
| B | PHE34 |
| B | LYS130 |
| B | ILE160 |
| B | LEU161 |
| B | GLY162 |
| site_id | AF4 |
| Number of Residues | 6 |
| Details | binding site for residue PEG B 416 |
| Chain | Residue |
| A | GLN115 |
| B | ARG210 |
| B | LEU355 |
| B | PHE356 |
| B | GLU357 |
| B | GLU360 |
| site_id | AF5 |
| Number of Residues | 8 |
| Details | binding site for residue PEG B 417 |
| Chain | Residue |
| B | LYS13 |
| B | GLY14 |
| B | TRP15 |
| B | ALA16 |
| B | PRO17 |
| B | ASP197 |
| B | GLU255 |
| B | HOH606 |
| site_id | AF6 |
| Number of Residues | 10 |
| Details | binding site for residue PEG B 418 |
| Chain | Residue |
| A | PRO111 |
| B | ALA205 |
| B | VAL236 |
| B | PRO237 |
| B | VAL238 |
| B | PHE239 |
| B | GLU240 |
| B | HOH520 |
| C | ASP59 |
| C | HOH534 |
| site_id | AF7 |
| Number of Residues | 6 |
| Details | binding site for residue PEG B 419 |
| Chain | Residue |
| B | SER190 |
| B | ILE191 |
| B | LEU192 |
| B | MET324 |
| B | GLY328 |
| B | PHE329 |
| site_id | AF8 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 420 |
| Chain | Residue |
| B | ALA2 |
| B | VAL4 |
| B | ASP5 |
| B | GLU6 |
| B | EDO411 |
| site_id | AF9 |
| Number of Residues | 7 |
| Details | binding site for residue PGE B 421 |
| Chain | Residue |
| B | LYS47 |
| B | ASN52 |
| B | GLN75 |
| B | ASP290 |
| B | EDO408 |
| B | HOH510 |
| C | ASP342 |
| site_id | AG1 |
| Number of Residues | 6 |
| Details | binding site for residue DMS B 422 |
| Chain | Residue |
| B | LYS13 |
| B | ALA199 |
| B | PHE239 |
| B | TYR253 |
| B | GLY254 |
| C | ASP59 |
| site_id | AG2 |
| Number of Residues | 5 |
| Details | binding site for residue DMS B 423 |
| Chain | Residue |
| B | SER86 |
| B | THR87 |
| B | ARG98 |
| B | CYS105 |
| B | EDO409 |
| site_id | AG3 |
| Number of Residues | 7 |
| Details | binding site for residue FES C 401 |
| Chain | Residue |
| C | CYS69 |
| C | HIS71 |
| C | ARG72 |
| C | CYS90 |
| C | TYR92 |
| C | HIS93 |
| C | TRP95 |
| site_id | AG4 |
| Number of Residues | 4 |
| Details | binding site for residue FE C 402 |
| Chain | Residue |
| C | HIS183 |
| C | HIS187 |
| C | ASP333 |
| C | 9G0403 |
| site_id | AG5 |
| Number of Residues | 13 |
| Details | binding site for residue 9G0 C 403 |
| Chain | Residue |
| C | GLY178 |
| C | HIS183 |
| C | ILE184 |
| C | HIS187 |
| C | ALA259 |
| C | ILE262 |
| C | VAL272 |
| C | PHE275 |
| C | GLN282 |
| C | ASN330 |
| C | ASP333 |
| C | FE402 |
| C | HOH506 |
| site_id | AG6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 404 |
| Chain | Residue |
| A | THR242 |
| C | ASP106 |
| C | ILE107 |
| C | LEU108 |
| C | PRO111 |
| C | ILE116 |
| C | HOH516 |
| site_id | AG7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 405 |
| Chain | Residue |
| C | ASN164 |
| C | EDO407 |
| site_id | AG8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 406 |
| Chain | Residue |
| C | LYS22 |
| C | ASN170 |
| C | ARG172 |
| C | GLU291 |
| C | HOH511 |
| C | HOH579 |
| site_id | AG9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 407 |
| Chain | Residue |
| C | PHE34 |
| C | GLU37 |
| C | LYS163 |
| C | ASN164 |
| C | EDO405 |
| C | PGE410 |
| C | HOH541 |
| site_id | AH1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 408 |
| Chain | Residue |
| C | GLU255 |
| C | SER370 |
| C | GLU371 |
| C | ASN373 |
| C | HOH574 |
| site_id | AH2 |
| Number of Residues | 2 |
| Details | binding site for residue PEG C 409 |
| Chain | Residue |
| C | PHE356 |
| C | GLU360 |
| site_id | AH3 |
| Number of Residues | 8 |
| Details | binding site for residue PGE C 410 |
| Chain | Residue |
| C | PHE34 |
| C | LYS36 |
| C | GLU37 |
| C | LYS130 |
| C | ILE160 |
| C | LEU161 |
| C | GLY162 |
| C | EDO407 |
