Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue FES A 401 |
| Chain | Residue |
| A | CYS69 |
| A | HIS71 |
| A | ARG72 |
| A | CYS90 |
| A | HIS93 |
| A | TRP95 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 402 |
| Chain | Residue |
| A | HOH596 |
| A | HOH621 |
| A | HOH632 |
| A | GLU100 |
| A | HOH555 |
| A | HOH556 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue FE2 A 403 |
| Chain | Residue |
| A | HIS183 |
| A | HIS187 |
| A | ASP333 |
| A | HOH624 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | LYS66 |
| A | ARG68 |
| A | LEU70 |
| A | LEU121 |
| A | LYS122 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 405 |
| Chain | Residue |
| A | ASP197 |
| A | ASP218 |
| A | TYR253 |
| A | GLU255 |
| A | GLU371 |
| A | HIS372 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 406 |
| Chain | Residue |
| A | GLU338 |
| A | VAL341 |
| A | ASP342 |
| A | HOH511 |
| A | HOH518 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 407 |
| Chain | Residue |
| A | ASP59 |
| A | GLY60 |
| C | PHE239 |
| C | TYR253 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 408 |
| Chain | Residue |
| A | PRO125 |
| A | VAL126 |
| A | HOH575 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 409 |
| Chain | Residue |
| A | SER86 |
| A | THR87 |
| A | ARG98 |
| A | CYS105 |
| A | HOH525 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 410 |
| Chain | Residue |
| A | LYS194 |
| A | ASP197 |
| A | GLU371 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 411 |
| Chain | Residue |
| A | LYS47 |
| A | ASN52 |
| A | GLN75 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue PEG A 412 |
| Chain | Residue |
| A | GLN75 |
| A | VAL78 |
| B | TRP335 |
| B | ALA339 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue PGE A 413 |
| Chain | Residue |
| A | ASN196 |
| A | LYS256 |
| A | ASN277 |
| A | LYS320 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue FES B 401 |
| Chain | Residue |
| B | CYS69 |
| B | HIS71 |
| B | ARG72 |
| B | CYS90 |
| B | HIS93 |
| B | TRP95 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 402 |
| Chain | Residue |
| B | ASP197 |
| B | TYR253 |
| B | HOH537 |
| B | HOH543 |
| B | HOH613 |
| B | HOH641 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue FE2 B 403 |
| Chain | Residue |
| B | HIS183 |
| B | HIS187 |
| B | ASP333 |
| B | OXY404 |
| site_id | AD8 |
| Number of Residues | 8 |
| Details | binding site for residue OXY B 404 |
| Chain | Residue |
| B | HIS183 |
| B | HIS187 |
| B | PHE329 |
| B | ASN330 |
| B | ASP333 |
| B | FE2403 |
| B | PGE410 |
| B | HOH592 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 405 |
| Chain | Residue |
| B | LYS168 |
| B | GLU338 |
| B | VAL341 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 406 |
| Chain | Residue |
| B | ARG210 |
| B | LEU355 |
| B | PHE356 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue PEG B 407 |
| Chain | Residue |
| B | LYS47 |
| B | ASN52 |
| B | GLN75 |
| B | HOH524 |
| C | ASP342 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for residue PEG B 408 |
| Chain | Residue |
| A | LYS211 |
| B | PHE34 |
| B | LYS36 |
| B | GLY162 |
| B | PHE317 |
| B | GLU318 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue PGE B 409 |
| Chain | Residue |
| B | GLN75 |
| B | SER77 |
| B | VAL78 |
| C | TRP335 |
| site_id | AE5 |
| Number of Residues | 7 |
| Details | binding site for residue PGE B 410 |
| Chain | Residue |
| B | ILE184 |
| B | LEU200 |
| B | ALA259 |
| B | PHE275 |
| B | PHE329 |
| B | ASN330 |
| B | OXY404 |
| site_id | AE6 |
| Number of Residues | 7 |
| Details | binding site for residue FES C 401 |
| Chain | Residue |
| C | CYS69 |
| C | HIS71 |
| C | ARG72 |
| C | CYS90 |
| C | TYR92 |
| C | HIS93 |
| C | TRP95 |
| site_id | AE7 |
| Number of Residues | 6 |
| Details | binding site for residue MG C 402 |
| Chain | Residue |
| C | GLU100 |
| C | HOH526 |
| C | HOH578 |
| C | HOH623 |
| C | HOH632 |
| C | HOH635 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue FE2 C 403 |
| Chain | Residue |
| C | HIS183 |
| C | HIS187 |
| C | ASP333 |
| C | OXY404 |
| site_id | AE9 |
| Number of Residues | 6 |
| Details | binding site for residue OXY C 404 |
| Chain | Residue |
| C | HIS183 |
| C | HIS187 |
| C | PHE329 |
| C | ASN330 |
| C | ASP333 |
| C | FE2403 |
| site_id | AF1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 405 |
| Chain | Residue |
| C | LYS66 |
| C | ARG68 |
| C | LEU121 |
| C | LYS122 |
| site_id | AF2 |
| Number of Residues | 5 |
| Details | binding site for residue PEG C 406 |
| Chain | Residue |
| A | ASP342 |
| C | LYS47 |
| C | ASN52 |
| C | GLN75 |
| C | HOH607 |
| site_id | AF3 |
| Number of Residues | 4 |
| Details | binding site for residue PEG C 407 |
| Chain | Residue |
| A | ASP156 |
| A | ASP157 |
| C | ASP155 |
| C | ASP157 |
| site_id | AF4 |
| Number of Residues | 4 |
| Details | binding site for residue PGE C 408 |
| Chain | Residue |
| C | GLU37 |
| C | LYS44 |
| C | THR45 |
| C | HOH586 |
| site_id | AF5 |
| Number of Residues | 8 |
| Details | binding site for residue PGE C 409 |
| Chain | Residue |
| A | ASP59 |
| A | TYR63 |
| A | LYS85 |
| A | SER86 |
| A | GLU100 |
| A | HOH543 |
| C | PHE239 |
| C | GLU240 |
| site_id | AF6 |
| Number of Residues | 4 |
| Details | binding site for residue DMS C 410 |
| Chain | Residue |
| C | GLU255 |
| C | SER370 |
| C | GLU371 |
| C | ASN373 |
