Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue FES A 401 |
| Chain | Residue |
| A | CYS69 |
| A | HIS71 |
| A | ARG72 |
| A | CYS90 |
| A | TYR92 |
| A | HIS93 |
| A | TRP95 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue FE2 A 402 |
| Chain | Residue |
| A | ASP333 |
| A | 9CA403 |
| A | HIS183 |
| A | HIS187 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue 9CA A 403 |
| Chain | Residue |
| A | GLY178 |
| A | HIS183 |
| A | ALA259 |
| A | ILE262 |
| A | LEU270 |
| A | PHE275 |
| A | GLN282 |
| A | GLU284 |
| A | PHE329 |
| A | ASN330 |
| A | FE2402 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | LEU161 |
| A | GLY162 |
| A | HOH506 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 405 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 406 |
| Chain | Residue |
| A | CYS82 |
| A | THR84 |
| A | LYS85 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 407 |
| Chain | Residue |
| A | LYS61 |
| C | GLU233 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 408 |
| Chain | Residue |
| A | ASN170 |
| A | ARG172 |
| A | GLU291 |
| A | HOH539 |
| A | HOH567 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 409 |
| Chain | Residue |
| A | THR84 |
| A | SER86 |
| B | ILE243 |
| B | GLU246 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 410 |
| Chain | Residue |
| A | ASN196 |
| A | LYS320 |
| A | PEG411 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 411 |
| Chain | Residue |
| A | LYS256 |
| A | ASN277 |
| A | EDO410 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 412 |
| Chain | Residue |
| A | LYS47 |
| A | ASN52 |
| B | ASP342 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue PGE A 413 |
| Chain | Residue |
| A | GLY14 |
| A | LYS367 |
| A | LEU368 |
| A | SER370 |
| A | GLU371 |
| A | HOH526 |
| B | GLU40 |
| site_id | AD5 |
| Number of Residues | 9 |
| Details | binding site for residue FES B 401 |
| Chain | Residue |
| B | CYS69 |
| B | HIS71 |
| B | ARG72 |
| B | VAL74 |
| B | CYS90 |
| B | TYR92 |
| B | HIS93 |
| B | ALA94 |
| B | TRP95 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue FE2 B 402 |
| Chain | Residue |
| B | HIS183 |
| B | HIS187 |
| B | ASP333 |
| B | HOH621 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 403 |
| Chain | Residue |
| B | ASP197 |
| B | TYR253 |
| B | HOH520 |
| B | HOH558 |
| B | HOH569 |
| B | HOH587 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 404 |
| Chain | Residue |
| A | VAL78 |
| B | TRP335 |
| B | ALA339 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 405 |
| Chain | Residue |
| B | LYS47 |
| B | ASN52 |
| B | EDO413 |
| C | ASP342 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 406 |
| Chain | Residue |
| B | ASP106 |
| B | ILE107 |
| B | LEU108 |
| B | PRO111 |
| B | ILE116 |
| C | THR242 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 407 |
| Chain | Residue |
| B | ASN164 |
| B | ILE166 |
| B | TYR295 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 408 |
| Chain | Residue |
| B | SER190 |
| B | ILE191 |
| B | LEU192 |
| B | MET324 |
| B | GLY328 |
| B | PHE329 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 409 |
| Chain | Residue |
| B | ARG249 |
| B | ALA252 |
| B | EDO411 |
| B | HOH561 |
| B | HOH569 |
| B | LYS188 |
| site_id | AE5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 410 |
| Chain | Residue |
| B | LYS13 |
| B | GLY14 |
| B | TRP15 |
| B | ALA16 |
| B | PRO17 |
| B | ASP197 |
| B | GLU255 |
| site_id | AE6 |
| Number of Residues | 10 |
| Details | binding site for residue EDO B 411 |
| Chain | Residue |
| B | LYS188 |
| B | LEU200 |
| B | PRO201 |
| B | LEU202 |
| B | ARG249 |
| B | GLU250 |
| B | GLY251 |
| B | ALA252 |
| B | EDO409 |
| B | HOH531 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 412 |
| Chain | Residue |
| B | TRP350 |
| B | VAL351 |
| B | GLU353 |
| B | LEU355 |
| B | HOH541 |
| site_id | AE8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 413 |
| Chain | Residue |
| B | LYS47 |
| B | GLY50 |
| B | GLU51 |
| B | ASN52 |
| B | EDO405 |
| B | HOH501 |
| site_id | AE9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 414 |
| Chain | Residue |
| B | ASN277 |
| B | GLU316 |
| B | GLU371 |
| B | HIS372 |
| site_id | AF1 |
| Number of Residues | 3 |
| Details | binding site for residue PEG B 415 |
| Chain | Residue |
| B | SER319 |
| B | MET324 |
| B | GLN374 |
| site_id | AF2 |
| Number of Residues | 7 |
| Details | binding site for residue FES C 401 |
| Chain | Residue |
| C | CYS69 |
| C | HIS71 |
| C | ARG72 |
| C | CYS90 |
| C | TYR92 |
| C | HIS93 |
| C | TRP95 |
| site_id | AF3 |
| Number of Residues | 3 |
| Details | binding site for residue FE2 C 402 |
| Chain | Residue |
| C | HIS183 |
| C | HIS187 |
| C | ASP333 |
| site_id | AF4 |
| Number of Residues | 12 |
| Details | binding site for residue 9CA C 403 |
| Chain | Residue |
| C | GLY178 |
| C | HIS183 |
| C | ILE184 |
| C | ALA259 |
| C | ILE262 |
| C | LEU270 |
| C | VAL272 |
| C | PHE275 |
| C | GLN282 |
| C | GLU284 |
| C | PHE329 |
| C | ASN330 |
| site_id | AF5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 404 |
| Chain | Residue |
| A | ASP342 |
| C | LYS47 |
| C | ASN52 |
| site_id | AF6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO C 405 |
| Chain | Residue |
| C | GLU37 |
| C | HOH566 |
| site_id | AF7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 406 |
| Chain | Residue |
| C | LEU23 |
| C | ASP290 |
| C | GLU291 |
| site_id | AF8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 407 |
| Chain | Residue |
| C | CYS82 |
| C | LYS83 |
| C | THR84 |
| C | LYS85 |
