6LKZ

Crystal structure of isocitrate dehydrogenase 1 from Phaeodactylum tricornutum

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0000287	molecular_function	magnesium ion binding
C	0004449	molecular_function	isocitrate dehydrogenase (NAD+) activity
C	0004450	molecular_function	isocitrate dehydrogenase (NADP+) activity
C	0005509	molecular_function	calcium ion binding
C	0005739	cellular_component	mitochondrion
C	0006099	biological_process	tricarboxylic acid cycle
C	0006102	biological_process	isocitrate metabolic process
C	0006739	biological_process	NADP+ metabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0019674	biological_process	NAD+ metabolic process
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0004449	molecular_function	isocitrate dehydrogenase (NAD+) activity
D	0004450	molecular_function	isocitrate dehydrogenase (NADP+) activity
D	0005509	molecular_function	calcium ion binding
D	0005739	cellular_component	mitochondrion
D	0006099	biological_process	tricarboxylic acid cycle
D	0006102	biological_process	isocitrate metabolic process
D	0006739	biological_process	NADP+ metabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0019674	biological_process	NAD+ metabolic process
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DKNGDGFIDfeEF

Chain	Residue	Details
C	ASP459-PHE471

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	70
Details	Domain: {"description":"EF-hand","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	42
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"A0A096P8D3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10142","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---