6LIS

ASFV dUTPase in complex with dUMP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004170	molecular_function	dUTP diphosphatase activity
A	0009117	biological_process	nucleotide metabolic process
A	0016787	molecular_function	hydrolase activity
A	0030430	cellular_component	host cell cytoplasm
A	0044423	cellular_component	virion component
A	0046872	molecular_function	metal ion binding
B	0004170	molecular_function	dUTP diphosphatase activity
B	0009117	biological_process	nucleotide metabolic process
B	0016787	molecular_function	hydrolase activity
B	0030430	cellular_component	host cell cytoplasm
B	0044423	cellular_component	virion component
B	0046872	molecular_function	metal ion binding
C	0004170	molecular_function	dUTP diphosphatase activity
C	0009117	biological_process	nucleotide metabolic process
C	0016787	molecular_function	hydrolase activity
C	0030430	cellular_component	host cell cytoplasm
C	0044423	cellular_component	virion component
C	0046872	molecular_function	metal ion binding
D	0004170	molecular_function	dUTP diphosphatase activity
D	0009117	biological_process	nucleotide metabolic process
D	0016787	molecular_function	hydrolase activity
D	0030430	cellular_component	host cell cytoplasm
D	0044423	cellular_component	virion component
D	0046872	molecular_function	metal ion binding
E	0004170	molecular_function	dUTP diphosphatase activity
E	0009117	biological_process	nucleotide metabolic process
E	0016787	molecular_function	hydrolase activity
E	0030430	cellular_component	host cell cytoplasm
E	0044423	cellular_component	virion component
E	0046872	molecular_function	metal ion binding
F	0004170	molecular_function	dUTP diphosphatase activity
F	0009117	biological_process	nucleotide metabolic process
F	0016787	molecular_function	hydrolase activity
F	0030430	cellular_component	host cell cytoplasm
F	0044423	cellular_component	virion component
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue UMP A 201

Chain	Residue
A	ASN85
B	SER72
B	HOH245
A	GLY88
A	ILE90
A	ASP91
A	MET99
A	HOH303
A	HOH304
A	HOH340
B	ARG71

---

site_id	AC2
Number of Residues	11
Details	binding site for residue UMP C 201

Chain	Residue
B	ASN85
B	GLY88
B	LEU89
B	ILE90
B	ASP91
B	TYR94
B	MET99
C	ARG71
C	SER72
C	HOH301
C	HOH348

---

site_id	AC3
Number of Residues	15
Details	binding site for residue UMP C 202

Chain	Residue
A	SER72
A	GLN120
A	HOH305
A	HOH332
C	ASN85
C	GLY88
C	LEU89
C	ILE90
C	ASP91
C	TYR94
C	MET99
C	HOH335
C	HOH346
C	HOH352
C	HOH368

---

site_id	AC4
Number of Residues	9
Details	binding site for residue UMP D 201

Chain	Residue
D	GLY88
D	LEU89
D	ILE90
D	ASP91
D	TYR94
D	MET99
D	HOH321
F	ARG71
F	SER72

---

site_id	AC5
Number of Residues	11
Details	binding site for residue UMP E 201

Chain	Residue
D	ARG71
D	SER72
E	ASN85
E	GLY88
E	ILE90
E	ASP91
E	TYR94
E	MET99
E	HOH329
E	HOH339
E	HOH344

---

site_id	AC6
Number of Residues	9
Details	binding site for residue UMP F 201

Chain	Residue
E	ARG71
E	SER72
F	ASN85
F	GLY88
F	ILE90
F	ASP91
F	TYR94
F	MET99
F	HOH324

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