6LE7

Crystal structure of nematode family I chitinase,CeCht1, in complex with dihydropyrrolopyrazol-6-one derivate 2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0005975	biological_process	carbohydrate metabolic process
A	0008061	molecular_function	chitin binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue EA9 A 501

Chain	Residue
A	TRP42
A	ARG284
A	GLU311
A	TRP374
A	PHE69
A	GLY117
A	TRP118
A	SER119
A	GLU159
A	MET225
A	TYR227
A	ASP228

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Functional Information from PROSITE/UniProt

site_id	PS01095
Number of Residues	9
Details	GH18_1 Glycosyl hydrolases family 18 (GH18) active site signature. FDGIDIDwE

Chain	Residue	Details
A	PHE151-GLU159

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000255|PROSITE-ProRule:PRU01258

Chain	Residue	Details
A	GLU159

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site_id	SWS_FT_FI2
Number of Residues	5
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01258

Chain	Residue	Details
A	ASP89
A	GLY116
A	TYR160
A	MET225
A	TRP374

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site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:12754521, ECO:0000269|PubMed:17761667

Chain	Residue	Details
A	ASN290

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