6LE7

Crystal structure of nematode family I chitinase,CeCht1, in complex with dihydropyrrolopyrazol-6-one derivate 2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0005975	biological_process	carbohydrate metabolic process
A	0008061	molecular_function	chitin binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue EA9 A 501

Chain	Residue
A	TRP42
A	ARG284
A	GLU311
A	TRP374
A	PHE69
A	GLY117
A	TRP118
A	SER119
A	GLU159
A	MET225
A	TYR227
A	ASP228

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Functional Information from PROSITE/UniProt

site_id	PS01095
Number of Residues	9
Details	GH18_1 Glycosyl hydrolases family 18 (GH18) active site signature. FDGIDIDwE

Chain	Residue	Details
A	PHE151-GLU159

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	373
Details	Domain: {"description":"GH18","evidences":[{"source":"PROSITE-ProRule","id":"PRU01258","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01258","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01258","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"12754521","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17761667","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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