6L6F

GluK3 receptor complex with UBP301

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001640	molecular_function	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
A	0004970	molecular_function	glutamate-gated receptor activity
A	0005216	molecular_function	monoatomic ion channel activity
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0006811	biological_process	monoatomic ion transport
A	0007196	biological_process	adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
A	0007215	biological_process	glutamate receptor signaling pathway
A	0007216	biological_process	G protein-coupled glutamate receptor signaling pathway
A	0007268	biological_process	chemical synaptic transmission
A	0008066	molecular_function	glutamate receptor activity
A	0015276	molecular_function	ligand-gated monoatomic ion channel activity
A	0015277	molecular_function	kainate selective glutamate receptor activity
A	0016020	cellular_component	membrane
A	0019722	biological_process	calcium-mediated signaling
A	0022849	molecular_function	glutamate-gated calcium ion channel activity
A	0030424	cellular_component	axon
A	0030425	cellular_component	dendrite
A	0032839	cellular_component	dendrite cytoplasm
A	0032983	cellular_component	kainate selective glutamate receptor complex
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0035235	biological_process	ionotropic glutamate receptor signaling pathway
A	0035249	biological_process	synaptic transmission, glutamatergic
A	0038023	molecular_function	signaling receptor activity
A	0042391	biological_process	regulation of membrane potential
A	0042734	cellular_component	presynaptic membrane
A	0043195	cellular_component	terminal bouton
A	0043204	cellular_component	perikaryon
A	0045202	cellular_component	synapse
A	0045211	cellular_component	postsynaptic membrane
A	0050804	biological_process	modulation of chemical synaptic transmission
A	0051967	biological_process	negative regulation of synaptic transmission, glutamatergic
A	0060078	biological_process	regulation of postsynaptic membrane potential
A	0098683	cellular_component	cochlear hair cell ribbon synapse
A	0098839	cellular_component	postsynaptic density membrane
A	0098978	cellular_component	glutamatergic synapse
A	0099505	biological_process	regulation of presynaptic membrane potential
A	0099507	molecular_function	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
A	1904315	molecular_function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
B	0001640	molecular_function	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
B	0004970	molecular_function	glutamate-gated receptor activity
B	0005216	molecular_function	monoatomic ion channel activity
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0006811	biological_process	monoatomic ion transport
B	0007196	biological_process	adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
B	0007215	biological_process	glutamate receptor signaling pathway
B	0007216	biological_process	G protein-coupled glutamate receptor signaling pathway
B	0007268	biological_process	chemical synaptic transmission
B	0008066	molecular_function	glutamate receptor activity
B	0015276	molecular_function	ligand-gated monoatomic ion channel activity
B	0015277	molecular_function	kainate selective glutamate receptor activity
B	0016020	cellular_component	membrane
B	0019722	biological_process	calcium-mediated signaling
B	0022849	molecular_function	glutamate-gated calcium ion channel activity
B	0030424	cellular_component	axon
B	0030425	cellular_component	dendrite
B	0032839	cellular_component	dendrite cytoplasm
B	0032983	cellular_component	kainate selective glutamate receptor complex
B	0034220	biological_process	monoatomic ion transmembrane transport
B	0035235	biological_process	ionotropic glutamate receptor signaling pathway
B	0035249	biological_process	synaptic transmission, glutamatergic
B	0038023	molecular_function	signaling receptor activity
B	0042391	biological_process	regulation of membrane potential
B	0042734	cellular_component	presynaptic membrane
B	0043195	cellular_component	terminal bouton
B	0043204	cellular_component	perikaryon
B	0045202	cellular_component	synapse
B	0045211	cellular_component	postsynaptic membrane
B	0050804	biological_process	modulation of chemical synaptic transmission
B	0051967	biological_process	negative regulation of synaptic transmission, glutamatergic
B	0060078	biological_process	regulation of postsynaptic membrane potential
B	0098683	cellular_component	cochlear hair cell ribbon synapse
B	0098839	cellular_component	postsynaptic density membrane
B	0098978	cellular_component	glutamatergic synapse
B	0099505	biological_process	regulation of presynaptic membrane potential
B	0099507	molecular_function	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
B	1904315	molecular_function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
C	0001640	molecular_function	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
C	0004970	molecular_function	glutamate-gated receptor activity
C	0005216	molecular_function	monoatomic ion channel activity
C	0005515	molecular_function	protein binding
C	0005886	cellular_component	plasma membrane
C	0006811	biological_process	monoatomic ion transport
C	0007196	biological_process	adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
C	0007215	biological_process	glutamate receptor signaling pathway
C	0007216	biological_process	G protein-coupled glutamate receptor signaling pathway
C	0007268	biological_process	chemical synaptic transmission
C	0008066	molecular_function	glutamate receptor activity
C	0015276	molecular_function	ligand-gated monoatomic ion channel activity
C	0015277	molecular_function	kainate selective glutamate receptor activity
C	0016020	cellular_component	membrane
C	0019722	biological_process	calcium-mediated signaling
C	0022849	molecular_function	glutamate-gated calcium ion channel activity
C	0030424	cellular_component	axon
C	0030425	cellular_component	dendrite
C	0032839	cellular_component	dendrite cytoplasm
C	0032983	cellular_component	kainate selective glutamate receptor complex
C	0034220	biological_process	monoatomic ion transmembrane transport
C	0035235	biological_process	ionotropic glutamate receptor signaling pathway
C	0035249	biological_process	synaptic transmission, glutamatergic
C	0038023	molecular_function	signaling receptor activity
C	0042391	biological_process	regulation of membrane potential
C	0042734	cellular_component	presynaptic membrane
C	0043195	cellular_component	terminal bouton
C	0043204	cellular_component	perikaryon
C	0045202	cellular_component	synapse
C	0045211	cellular_component	postsynaptic membrane
C	0050804	biological_process	modulation of chemical synaptic transmission
C	0051967	biological_process	negative regulation of synaptic transmission, glutamatergic
C	0060078	biological_process	regulation of postsynaptic membrane potential
C	0098683	cellular_component	cochlear hair cell ribbon synapse
C	0098839	cellular_component	postsynaptic density membrane
C	0098978	cellular_component	glutamatergic synapse
C	0099505	biological_process	regulation of presynaptic membrane potential
C	0099507	molecular_function	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
C	1904315	molecular_function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
D	0001640	molecular_function	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
D	0004970	molecular_function	glutamate-gated receptor activity
D	0005216	molecular_function	monoatomic ion channel activity
D	0005515	molecular_function	protein binding
D	0005886	cellular_component	plasma membrane
D	0006811	biological_process	monoatomic ion transport
D	0007196	biological_process	adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
D	0007215	biological_process	glutamate receptor signaling pathway
D	0007216	biological_process	G protein-coupled glutamate receptor signaling pathway
D	0007268	biological_process	chemical synaptic transmission
D	0008066	molecular_function	glutamate receptor activity
D	0015276	molecular_function	ligand-gated monoatomic ion channel activity
D	0015277	molecular_function	kainate selective glutamate receptor activity
D	0016020	cellular_component	membrane
D	0019722	biological_process	calcium-mediated signaling
D	0022849	molecular_function	glutamate-gated calcium ion channel activity
D	0030424	cellular_component	axon
D	0030425	cellular_component	dendrite
D	0032839	cellular_component	dendrite cytoplasm
D	0032983	cellular_component	kainate selective glutamate receptor complex
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0035235	biological_process	ionotropic glutamate receptor signaling pathway
D	0035249	biological_process	synaptic transmission, glutamatergic
D	0038023	molecular_function	signaling receptor activity
D	0042391	biological_process	regulation of membrane potential
D	0042734	cellular_component	presynaptic membrane
D	0043195	cellular_component	terminal bouton
D	0043204	cellular_component	perikaryon
D	0045202	cellular_component	synapse
D	0045211	cellular_component	postsynaptic membrane
D	0050804	biological_process	modulation of chemical synaptic transmission
D	0051967	biological_process	negative regulation of synaptic transmission, glutamatergic
D	0060078	biological_process	regulation of postsynaptic membrane potential
D	0098683	cellular_component	cochlear hair cell ribbon synapse
D	0098839	cellular_component	postsynaptic density membrane
D	0098978	cellular_component	glutamatergic synapse
D	0099505	biological_process	regulation of presynaptic membrane potential
D	0099507	molecular_function	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
D	1904315	molecular_function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21907808","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3S9E","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	160
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	8
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"20951142","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI7
Number of Residues	24
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI8
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"20951142","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24090084","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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